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    Results: 1 to 20 of 282

    1.

    The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

    Thong FS, Bilan PJ, Klip A.

    Diabetes. 2007 Feb;56(2):414-23.PMID: 17259386 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation.

    Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE.

    J Biol Chem. 2008 Apr 4;283(14):9187-95. Epub 2008 Feb 7.PMID: 18258599 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.

    Kramer HF, Witczak CA, Fujii N, Jessen N, Taylor EB, Arnolds DE, Sakamoto K, Hirshman MF, Goodyear LJ.

    Diabetes. 2006 Jul;55(7):2067-76.PMID: 16804077 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells.

    Ishikura S, Bilan PJ, Klip A.

    Biochem Biophys Res Commun. 2007 Feb 23;353(4):1074-9. Epub 2006 Dec 27.PMID: 17208202 [PubMed - indexed for MEDLINE]Related articles

    5.

    A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.

    Ramm G, Larance M, Guilhaus M, James DE.

    J Biol Chem. 2006 Sep 29;281(39):29174-80. Epub 2006 Jul 31.PMID: 16880201 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

    Cartee GD, Wojtaszewski JF.

    Appl Physiol Nutr Metab. 2007 Jun;32(3):557-66. Review.PMID: 17510697 [PubMed - indexed for MEDLINE]Related articles

    7.

    Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.

    Stöckli J, Davey JR, Hohnen-Behrens C, Xu A, James DE, Ramm G.

    Mol Endocrinol. 2008 Dec;22(12):2703-15. Epub 2008 Sep 18.PMID: 18801932 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

    Taylor EB, An D, Kramer HF, Yu H, Fujii NL, Roeckl KS, Bowles N, Hirshman MF, Xie J, Feener EP, Goodyear LJ.

    J Biol Chem. 2008 Apr 11;283(15):9787-96. Epub 2008 Feb 13.PMID: 18276596 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation.

    Ishikura S, Klip A.

    Am J Physiol Cell Physiol. 2008 Oct;295(4):C1016-25. Epub 2008 Aug 13.PMID: 18701652 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    The Rab GTPase-activating protein AS160 as a common regulator of insulin- and Galphaq-mediated intracellular GLUT4 vesicle distribution.

    Yuasa T, Uchiyama K, Ogura Y, Kimura M, Teshigawara K, Hosaka T, Tanaka Y, Obata T, Sano H, Kishi K, Ebina Y.

    Endocr J. 2009 Jun;56(3):345-59. Epub 2009 Jan 9.PMID: 19139597 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain.

    Mîinea CP, Sano H, Kane S, Sano E, Fukuda M, Peränen J, Lane WS, Lienhard GE.

    Biochem J. 2005 Oct 1;391(Pt 1):87-93.PMID: 15971998 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

    Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

    Diabetes. 2008 May;57(5):1195-204. Epub 2008 Feb 14.PMID: 18276765 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A in muscle cells.

    Randhawa VK, Ishikura S, Talior-Volodarsky I, Cheng AW, Patel N, Hartwig JH, Klip A.

    J Biol Chem. 2008 Oct 3;283(40):27208-19. Epub 2008 Jul 23.PMID: 18650435 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Muscle cell depolarization induces a gain in surface GLUT4 via reduced endocytosis independently of AMPK.

    Wijesekara N, Tung A, Thong F, Klip A.

    Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1276-86. Epub 2006 Jan 17.PMID: 16418206 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic.

    Sakamoto K, Holman GD.

    Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E29-37. Epub 2008 May 13. Review.PMID: 18477703 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The glucose transporter 4 FQQI motif is necessary for Akt substrate of 160-kilodalton-dependent plasma membrane translocation but not Golgi-localized (gamma)-ear-containing Arf-binding protein-dependent entry into the insulin-responsive storage compartment.

    Capilla E, Suzuki N, Pessin JE, Hou JC.

    Mol Endocrinol. 2007 Dec;21(12):3087-99. Epub 2007 Aug 30.PMID: 17761952 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Selective regulation of the perinuclear distribution of glucose transporter 4 (GLUT4) by insulin signals in muscle cells.

    Dugani CB, Randhawa VK, Cheng AW, Patel N, Klip A.

    Eur J Cell Biol. 2008 Jun;87(6):337-51. Epub 2008 Apr 15.PMID: 18417252 [PubMed - indexed for MEDLINE]Related articles

    18.

    Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR.

    Geraghty KM, Chen S, Harthill JE, Ibrahim AF, Toth R, Morrice NA, Vandermoere F, Moorhead GB, Hardie DG, MacKintosh C.

    Biochem J. 2007 Oct 15;407(2):231-41.PMID: 17617058 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Small G proteins in insulin action: Rab and Rho families at the crossroads of signal transduction and GLUT4 vesicle traffic.

    Ishikura S, Koshkina A, Klip A.

    Acta Physiol (Oxf). 2008 Jan;192(1):61-74. Review.PMID: 18171430 [PubMed - indexed for MEDLINE]Related articles

    20.

    Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.

    Sano H, Kane S, Sano E, Mîinea CP, Asara JM, Lane WS, Garner CW, Lienhard GE.

    J Biol Chem. 2003 Apr 25;278(17):14599-602. Epub 2003 Mar 11.PMID: 12637568 [PubMed - indexed for MEDLINE]Related articlesFree article

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