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Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells.
JeBailey L, Wanono O, Niu W, Roessler J, Rudich A, Klip A.
Diabetes. 2007 Feb;56(2):394-403.PMID: 17259384 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.
Summers SA, Garza LA, Zhou H, Birnbaum MJ.
Mol Cell Biol. 1998 Sep;18(9):5457-64.PMID: 9710629 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.
Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB.
Diabetes. 1999 Feb;48(2):310-20.PMID: 10334307 [PubMed - indexed for MEDLINE]Related articlesFree article
Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling.
JeBailey L, Rudich A, Huang X, Di Ciano-Oliveira C, Kapus A, Klip A.
Mol Endocrinol. 2004 Feb;18(2):359-72. Epub 2003 Nov 13.PMID: 14615606 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes.
Huang C, Thirone AC, Huang X, Klip A.
J Biol Chem. 2005 May 13;280(19):19426-35. Epub 2005 Mar 11.PMID: 15764603 [PubMed - indexed for MEDLINE]Related articlesFree article
Growth hormone inhibition of glucose uptake in adipocytes occurs without affecting GLUT4 translocation through an insulin receptor substrate-2-phosphatidylinositol 3-kinase-dependent pathway.
Sasaki-Suzuki N, Arai K, Ogata T, Kasahara K, Sakoda H, Chida K, Asano T, Pessin JE, Hakuno F, Takahashi S.
J Biol Chem. 2009 Mar 6;284(10):6061-70. Epub 2009 Jan 2.PMID: 19122000 [PubMed - indexed for MEDLINE]Related articles
Eicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elements.
Dransfeld O, Rakatzi I, Sasson S, Gruzman A, Schmitt M, Häussinger D, Eckel J.
Biochem J. 2001 Oct 1;359(Pt 1):47-54.PMID: 11563968 [PubMed - indexed for MEDLINE]Related articlesFree article
The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.
Hribal ML, Federici M, Porzio O, Lauro D, Borboni P, Accili D, Lauro R, Sesti G.
J Clin Endocrinol Metab. 2000 May;85(5):2004-13.PMID: 10843189 [PubMed - indexed for MEDLINE]Related articlesFree article
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.
Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS.
Diabetologia. 2001 Feb;44(2):173-83.PMID: 11270673 [PubMed - indexed for MEDLINE]Related articles
Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake.
Storz P, Döppler H, Wernig A, Pfizenmaier K, Müller G.
Eur J Biochem. 1999 Nov;266(1):17-25.PMID: 10542046 [PubMed - indexed for MEDLINE]Related articlesFree article
High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells.
Sweeney G, Keen J, Somwar R, Konrad D, Garg R, Klip A.
Endocrinology. 2001 Nov;142(11):4806-12.PMID: 11606447 [PubMed - indexed for MEDLINE]Related articlesFree article
Intracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cells.
Patel N, Rudich A, Khayat ZA, Garg R, Klip A.
Mol Cell Biol. 2003 Jul;23(13):4611-26.PMID: 12808101 [PubMed - indexed for MEDLINE]Related articlesFree article
Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities.
Tremblay F, Lavigne C, Jacques H, Marette A.
Diabetes. 2001 Aug;50(8):1901-10.PMID: 11473054 [PubMed - indexed for MEDLINE]Related articlesFree article
Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner.
de Alvaro C, Teruel T, Hernandez R, Lorenzo M.
J Biol Chem. 2004 Apr 23;279(17):17070-8. Epub 2004 Feb 4.PMID: 14764603 [PubMed - indexed for MEDLINE]Related articlesFree article
Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues.
Brozinick JT Jr, Hawkins ED, Strawbridge AB, Elmendorf JS.
J Biol Chem. 2004 Sep 24;279(39):40699-706. Epub 2004 Jul 6.PMID: 15247264 [PubMed - indexed for MEDLINE]Related articlesFree article
Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts.
Török D, Patel N, Jebailey L, Thong FS, Randhawa VK, Klip A, Rudich A.
J Cell Sci. 2004 Oct 15;117(Pt 22):5447-55. Epub 2004 Oct 5.PMID: 15466888 [PubMed - indexed for MEDLINE]Related articlesFree article
Involvement of the actin network in insulin signalling.
Tsakiridis T, Wang Q, Taha C, Grinstein S, Downey G, Klip A.
Soc Gen Physiol Ser. 1997;52:257-71.PMID: 9210235 [PubMed - indexed for MEDLINE]Related articles
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes.
Mahadev K, Wu X, Zilbering A, Zhu L, Lawrence JT, Goldstein BJ.
J Biol Chem. 2001 Dec 28;276(52):48662-9. Epub 2001 Oct 11.PMID: 11598110 [PubMed - indexed for MEDLINE]Related articlesFree article
Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity.
Bazuine M, Ouwens DM, Gomes de Mesquita DS, Maassen JA.
Eur J Biochem. 2003 Oct;270(19):3891-903.PMID: 14511371 [PubMed - indexed for MEDLINE]Related articlesFree article
Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells.
Liu LZ, Zhao HL, Zuo J, Ho SK, Chan JC, Meng Y, Fang FD, Tong PC.
Mol Biol Cell. 2006 May;17(5):2322-30. Epub 2006 Mar 8.PMID: 16525020 [PubMed - indexed for MEDLINE]Related articlesFree article
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