PubMed

Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans.

Lehman DM, Hunt KJ, Leach RJ, Hamlington J, Arya R, Abboud HE, Duggirala R, Blangero J, Göring HH, Stern MP.

Diabetes. 2007 Feb;56(2):389-93.PMID: 17259383 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohankrishna P, Hattersley AT, Frayling TM, Yajnik CS.

Diabetologia. 2007 Jan;50(1):63-7. Epub 2006 Nov 9.PMID: 17093941 [PubMed - indexed for MEDLINE]Related articles

P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans.

Lehman DM, Richardson DK, Jenkinson CP, Hunt KJ, Dyer TD, Leach RJ, Arya R, Abboud HE, Blangero J, Duggirala R, Stern MP.

Diabetes. 2007 Feb;56(2):513-7.PMID: 17259399 [PubMed - indexed for MEDLINE]Related articlesFree article

Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.

Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, Chuang LM.

Diabetes. 2007 Oct;56(10):2631-7. Epub 2007 Jun 19.PMID: 17579206 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort.

van Vliet-Ostaptchouk JV, Shiri-Sverdlov R, Zhernakova A, Strengman E, van Haeften TW, Hofker MH, Wijmenga C.

Diabetologia. 2007 Jan;50(1):59-62. Epub 2006 Oct 10.PMID: 17031610 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

Diabetes. 2006 Sep;55(9):2654-9.PMID: 16936218 [PubMed - indexed for MEDLINE]Related articlesFree article

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Nagai R, Froguel P, Kadowaki T.

Diabetologia. 2007 Apr;50(4):747-51. Epub 2007 Jan 24.PMID: 17245589 [PubMed - indexed for MEDLINE]Related articles

Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population.

Ren Q, Han XY, Wang F, Zhang XY, Han LC, Luo YY, Zhou XH, Ji LN.

Diabetologia. 2008 Jul;51(7):1146-52. Epub 2008 May 21.PMID: 18493736 [PubMed - indexed for MEDLINE]Related articles

Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.

Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI.

Diabetes. 2007 Oct;56(10):2638-42. Epub 2007 Jun 29.PMID: 17601994 [PubMed - indexed for MEDLINE]Related articlesFree article

Loci of TCF7L2, HHEX and IDE on chromosome 10q and the susceptibility of their genetic polymorphisms to type 2 diabetes.

Nordman S, Ostenson CG, Efendic S, Gu HF.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):186-90. Epub 2008 Dec 3.PMID: 19053027 [PubMed - indexed for MEDLINE]Related articles

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M.

Diabetes. 2006 Sep;55(9):2649-53.PMID: 16936217 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.

Rees SD, Bellary S, Britten AC, O'Hare JP, Kumar S, Barnett AH, Kelly MA.

BMC Med Genet. 2008 Feb 21;9:8.PMID: 18291022 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.

Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW.

Diabetes. 2008 Aug;57(8):2220-5. Epub 2008 Apr 28.PMID: 18443202 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 polymorphisms are associated with type 2 diabetes in Khatri Sikhs from North India: genetic variation affects lipid levels.

Sanghera DK, Nath SK, Ortega L, Gambarelli M, Kim-Howard X, Singh JR, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Kamboh MI.

Ann Hum Genet. 2008 Jul;72(Pt 4):499-509. Epub 2008 Apr 7.PMID: 18397358 [PubMed - indexed for MEDLINE]Related articles

Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women.

Humphries SE, Gable D, Cooper JA, Ireland H, Stephens JW, Hurel SJ, Li KW, Palmen J, Miller MA, Cappuccio FP, Elkeles R, Godsland I, Miller GJ, Talmud PJ.

J Mol Med. 2006 Dec;84(12):1005-14.PMID: 17665514 [PubMed - indexed for MEDLINE]Related articles

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K.

Nat Genet. 2006 Mar;38(3):320-3. Epub 2006 Jan 15.PMID: 16415884 [PubMed - indexed for MEDLINE]Related articles

Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese.

Ng MC, Tam CH, Lam VK, So WY, Ma RC, Chan JC.

J Clin Endocrinol Metab. 2007 Sep;92(9):3733-7. Epub 2007 Jul 3.PMID: 17609304 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes.

Yu J, Steck AK, Babu S, Yu L, Miao D, McFann K, Hutton J, Eisenbarth GS, Klingensmith G.

J Clin Endocrinol Metab. 2009 Feb;94(2):504-10. Epub 2008 Dec 2.PMID: 19050058 [PubMed - indexed for MEDLINE]Related articles

Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects.

Miyake K, Horikawa Y, Hara K, Yasuda K, Osawa H, Furuta H, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Makino H, Nanjo K, Kadowaki T, Kasuga M.

J Hum Genet. 2008;53(2):174-80. Epub 2007 Dec 21.PMID: 18097733 [PubMed - indexed for MEDLINE]Related articles

Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.

Dahlgren A, Zethelius B, Jensevik K, Syvänen AC, Berne C; ULSAM Cohort.

Diabetologia. 2007 Sep;50(9):1852-7. Epub 2007 Jul 6.PMID: 17618413 [PubMed - indexed for MEDLINE]Related articles