PubMed

Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model.

Meier M, Park JK, Overheu D, Kirsch T, Lindschau C, Gueler F, Leitges M, Menne J, Haller H.

Diabetes. 2007 Feb;56(2):346-54.PMID: 17259378 [PubMed - indexed for MEDLINE]Related articlesFree article

Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice.

Menne J, Park JK, Boehne M, Elger M, Lindschau C, Kirsch T, Meier M, Gueler F, Fiebeler A, Bahlmann FH, Leitges M, Haller H.

Diabetes. 2004 Aug;53(8):2101-9.PMID: 15277392 [PubMed - indexed for MEDLINE]Related articlesFree article

p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency.

Wolf G, Schanze A, Stahl RA, Shankland SJ, Amann K.

Kidney Int. 2005 Oct;68(4):1583-9.PMID: 16164635 [PubMed - indexed for MEDLINE]Related articles

Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo.

Meier M, Menne J, Park JK, Holtz M, Gueler F, Kirsch T, Schiffer M, Mengel M, Lindschau C, Leitges M, Haller H.

J Am Soc Nephrol. 2007 Apr;18(4):1190-8. Epub 2007 Mar 14.PMID: 17360953 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.

Ohshiro Y, Ma RC, Yasuda Y, Hiraoka-Yamamoto J, Clermont AC, Isshiki K, Yagi K, Arikawa E, Kern TS, King GL.

Diabetes. 2006 Nov;55(11):3112-20.PMID: 17065350 [PubMed - indexed for MEDLINE]Related articlesFree article

Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.

Wang A, Ziyadeh FN, Lee EY, Pyagay PE, Sung SH, Sheardown SA, Laping NJ, Chen S.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1657-65. Epub 2007 Sep 5.PMID: 17804483 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.

Cohen MP, Chen S, Ziyadeh FN, Shea E, Hud EA, Lautenslager GT, Shearman CW.

Kidney Int. 2005 Oct;68(4):1554-61.PMID: 16164632 [PubMed - indexed for MEDLINE]Related articles

Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.

Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R.

FASEB J. 2000 Mar;14(3):439-47.PMID: 10698958 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.

Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H.

Diabetes. 2005 Oct;54(10):2891-903. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16186390 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.

Iglesias-de la Cruz MC, Ziyadeh FN, Isono M, Kouahou M, Han DC, Kalluri R, Mundel P, Chen S.

Kidney Int. 2002 Sep;62(3):901-13.PMID: 12164872 [PubMed - indexed for MEDLINE]Related articlesFree article

Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice.

Sharma K, Jin Y, Guo J, Ziyadeh FN.

Diabetes. 1996 Apr;45(4):522-30.PMID: 8603776 [PubMed - indexed for MEDLINE]Related articles

Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor.

Russo LM, del Re E, Brown D, Lin HY.

Diabetes. 2007 Feb;56(2):380-8.PMID: 17259382 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy.

Fujimoto M, Maezawa Y, Yokote K, Joh K, Kobayashi K, Kawamura H, Nishimura M, Roberts AB, Saito Y, Mori S.

Biochem Biophys Res Commun. 2003 Jun 13;305(4):1002-7.PMID: 12767930 [PubMed - indexed for MEDLINE]Related articles

Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo.

Menne J, Meier M, Park JK, Boehne M, Kirsch T, Lindschau C, Ociepka R, Leitges M, Rinta-Valkama J, Holthofer H, Haller H.

Kidney Int. 2006 Oct;70(8):1456-62. Epub 2006 Sep 6.PMID: 16955103 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha.

Lindschau C, Quass P, Menne J, Güler F, Fiebeler A, Leitges M, Luft FC, Haller H.

Hypertension. 2003 Sep;42(3):335-41. Epub 2003 Aug 25.PMID: 12939231 [PubMed - indexed for MEDLINE]Related articlesFree article

The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy.

Al-Douahji M, Brugarolas J, Brown PA, Stehman-Breen CO, Alpers CE, Shankland SJ.

Kidney Int. 1999 Nov;56(5):1691-9.PMID: 10571777 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation.

Usui HK, Shikata K, Sasaki M, Okada S, Matsuda M, Shikata Y, Ogawa D, Kido Y, Nagase R, Yozai K, Ohga S, Tone A, Wada J, Takeya M, Horiuchi S, Kodama T, Makino H.

Diabetes. 2007 Feb;56(2):363-72. Erratum in: Diabetes. 2007 Mar;56(3):897. Takeya, Masahiro [corrected to Takeya, Motohiro]. PMID: 17259380 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-induced upregulation of urotensin II and its receptor plays an important role in TGF-beta1-mediated renal fibrosis and dysfunction.

Tian L, Li C, Qi J, Fu P, Yu X, Li X, Cai L.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1234-42. Epub 2008 Sep 16.PMID: 18796544 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury.

Liu S, Shi L, Wang S.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1727-35. Epub 2007 Sep 19.PMID: 17881461 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products.

Lassila M, Seah KK, Allen TJ, Thallas V, Thomas MC, Candido R, Burns WC, Forbes JM, Calkin AC, Cooper ME, Jandeleit-Dahm KA.

J Am Soc Nephrol. 2004 Aug;15(8):2125-38.PMID: 15284298 [PubMed - indexed for MEDLINE]Related articlesFree article