PubMed

Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages.

Askari B, Kanter JE, Sherrid AM, Golej DL, Bender AT, Liu J, Hsueh WA, Beavo JA, Coleman RA, Bornfeldt KE.

Diabetes. 2007 Apr;56(4):1143-52. Epub 2007 Jan 26.PMID: 17259370 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone inhibits angiotensin II-induced CTGF expression in vascular smooth muscle cells - role of PPAR-gamma in vascular fibrosis.

Gao DF, Niu XL, Hao GH, Peng N, Wei J, Ning N, Wang NP.

Biochem Pharmacol. 2007 Jan 15;73(2):185-97. Epub 2006 Sep 23.PMID: 17074304 [PubMed - indexed for MEDLINE]Related articles

Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.

Durgan DJ, Smith JK, Hotze MA, Egbejimi O, Cuthbert KD, Zaha VG, Dyck JR, Abel ED, Young ME.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2480-97. Epub 2006 Jan 20.PMID: 16428347 [PubMed - indexed for MEDLINE]Related articlesFree article

Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells.

Mashek DG, McKenzie MA, Van Horn CG, Coleman RA.

J Biol Chem. 2006 Jan 13;281(2):945-50. Epub 2005 Nov 1.PMID: 16263710 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of recombinant long-chain rat acyl-CoA synthetase isoforms 3 and 6: identification of a novel variant of isoform 6.

Van Horn CG, Caviglia JM, Li LO, Wang S, Granger DA, Coleman RA.

Biochemistry. 2005 Feb 8;44(5):1635-42.PMID: 15683247 [PubMed - indexed for MEDLINE]Related articles

Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects.

Westerbacka J, Kolak M, Kiviluoto T, Arkkila P, Sirén J, Hamsten A, Fisher RM, Yki-Järvinen H.

Diabetes. 2007 Nov;56(11):2759-65. Epub 2007 Aug 17.PMID: 17704301 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma response element activity in intact primary human adipocytes: effects of fatty acids.

Sauma L, Stenkula KG, Kjølhede P, Strålfors P, Söderström M, Nystrom FH.

Nutrition. 2006 Jan;22(1):60-8. Epub 2005 Oct 12.PMID: 16226011 [PubMed - indexed for MEDLINE]Related articles

Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model.

Kim HJ, Jung TW, Kang ES, Kim DJ, Ahn CW, Lee KW, Lee HC, Cha BS.

Metabolism. 2007 May;56(5):676-85.PMID: 17445544 [PubMed - indexed for MEDLINE]Related articles

Antidiabetic and hypolipidemic potential of DRF 2519--a dual activator of PPAR-alpha and PPAR-gamma.

Chakrabarti R, Misra P, Vikramadithyan RK, Premkumar M, Hiriyan J, Datla SR, Damarla RK, Suresh J, Rajagopalan R.

Eur J Pharmacol. 2004 May 3;491(2-3):195-206.PMID: 15140637 [PubMed - indexed for MEDLINE]Related articles

Lipid synthesis in macrophages during inflammation in vivo: effect of agonists of peroxisome proliferator activated receptors alpha and gamma and of retinoid X receptors.

Posokhova EN, Khoshchenko OM, Chasovskikh MI, Pivovarova EN, Dushkin MI.

Biochemistry (Mosc). 2008 Mar;73(3):296-304.PMID: 18393765 [PubMed - indexed for MEDLINE]Related articles

Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway.

Díaz-Delfín J, Morales M, Caelles C.

Diabetes. 2007 Jul;56(7):1865-71. Epub 2007 Apr 6.PMID: 17416798 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma.

Risérus U, Tan GD, Fielding BA, Neville MJ, Currie J, Savage DB, Chatterjee VK, Frayn KN, O'Rahilly S, Karpe F.

Diabetes. 2005 May;54(5):1379-84.PMID: 15855323 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.

Stienstra R, Duval C, Keshtkar S, van der Laak J, Kersten S, Müller M.

J Biol Chem. 2008 Aug 15;283(33):22620-7. Epub 2008 Jun 9.PMID: 18541527 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and characterization of recombinant rat Acyl-CoA synthetases 1, 4, and 5. Selective inhibition by triacsin C and thiazolidinediones.

Kim JH, Lewin TM, Coleman RA.

J Biol Chem. 2001 Jul 6;276(27):24667-73. Epub 2001 Apr 23.PMID: 11319222 [PubMed - indexed for MEDLINE]Related articles

Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin.

Ye JM, Dzamko N, Cleasby ME, Hegarty BD, Furler SM, Cooney GJ, Kraegen EW.

Diabetologia. 2004 Jul;47(7):1306-13. Epub 2004 Jul 1.PMID: 15232684 [PubMed - indexed for MEDLINE]Related articles

Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma expression in pituitary tumours and the functional activity of the glitazones: evidence that any anti-proliferative effect of the glitazones is independent of the PPAR-gamma receptor.

Emery MN, Leontiou C, Bonner SE, Merulli C, Nanzer AM, Musat M, Galloway M, Powell M, Nikookam K, Korbonits M, Grossman AB.

Clin Endocrinol (Oxf). 2006 Sep;65(3):389-95.PMID: 16918962 [PubMed - indexed for MEDLINE]Related articles

Oxidized lipid-driven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells through a peroxisome proliferator-activated receptor gamma-dependent pathway.

Barlic J, Zhang Y, Foley JF, Murphy PM.

Circulation. 2006 Aug 22;114(8):807-19. Epub 2006 Aug 14.PMID: 16908772 [PubMed - indexed for MEDLINE]Related articlesFree article

Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells.

Yu HY, Inoguchi T, Kakimoto M, Nakashima N, Imamura M, Hashimoto T, Umeda F, Nawata H.

Diabetologia. 2001 May;44(5):614-20.PMID: 11380080 [PubMed - indexed for MEDLINE]Related articles

Activation of peroxisome proliferator-activated receptor gamma inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer.

Lin MS, Chen WC, Bai X, Wang YD.

J Dig Dis. 2007 May;8(2):82-8.PMID: 17532820 [PubMed - indexed for MEDLINE]Related articles