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    Results: 1 to 20 of 73

    1.

    Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes.

    Hill NJ, Stotland A, Solomon M, Secrest P, Getzoff E, Sarvetnick N.

    Biol Direct. 2007 Jan 25;2:5.

    PMID:
    17254331
    [PubMed]
    Free PMC Article
    2.

    Genetic and therapeutic control of diabetogenic CD8+ T cells.

    Santamaria P.

    Novartis Found Symp. 2008;292:130-6; discussion 136-45, 202-3.

    PMID:
    19209463
    [PubMed - indexed for MEDLINE]
    3.

    Rotavirus infection accelerates type 1 diabetes in mice with established insulitis.

    Graham KL, Sanders N, Tan Y, Allison J, Kay TW, Coulson BS.

    J Virol. 2008 Jul;82(13):6139-49. Epub 2008 Apr 16.

    PMID:
    18417562
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection.

    Rønn SG, Börjesson A, Bruun C, Heding PE, Frobøse H, Mandrup-Poulsen T, Karlsen AE, Rasschaert J, Sandler S, Billestrup N.

    Diabetologia. 2008 Oct;51(10):1873-82. Epub 2008 Jul 22.

    PMID:
    18648765
    [PubMed - indexed for MEDLINE]
    5.

    The role of the gut in beta-cell autoimmunity and type 1 diabetes: a hypothesis.

    Vaarala O.

    Pediatr Diabetes. 2000 Dec;1(4):217-25.

    PMID:
    15016219
    [PubMed]
    6.

    Update on diabetes mellitus.

    Korc M.

    Dis Markers. 2004;20(3):161-5. Review.

    PMID:
    15502249
    [PubMed - indexed for MEDLINE]
    7.

    The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

    Hultcrantz M, Jacobson S, Hill NJ, Santamaria P, Flodström-Tullberg M.

    Diabetologia. 2009 Feb;52(2):299-305. Epub 2008 Nov 25.

    PMID:
    19031069
    [PubMed - indexed for MEDLINE]
    8.

    Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice.

    Sgouroudis E, Albanese A, Piccirillo CA.

    J Immunol. 2008 Nov 1;181(9):6283-92.

    PMID:
    18941219
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    In vivo effects of cytokines on pancreatic beta-cells in models of type I diabetes dependent on CD4(+) T lymphocytes.

    Angstetra E, Graham KL, Emmett S, Dudek NL, Darwiche R, Ayala-Perez R, Allison J, Santamaria P, Kay TW, Thomas HE.

    Immunol Cell Biol. 2009 Feb;87(2):178-85. Epub 2008 Nov 18.

    PMID:
    19015667
    [PubMed - indexed for MEDLINE]
    10.

    Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.

    Riboulet-Chavey A, Diraison F, Siew LK, Wong FS, Rutter GA.

    Diabetes. 2008 Feb;57(2):415-23. Epub 2007 Nov 14.

    PMID:
    18003756
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.

    Callewaert HI, Gysemans CA, Ladrière L, D'Hertog W, Hagenbrock J, Overbergh L, Eizirik DL, Mathieu C.

    Diabetes. 2007 Aug;56(8):2169-73. Epub 2007 May 1.

    PMID:
    17473223
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Cyclin-dependent kinase 4 hyperactivity promotes autoreactivity in the immune system but protects pancreatic cell mass from autoimmune destruction in the nonobese diabetic mouse model.

    Marzo N, Ortega S, Stratmann T, García A, Ríos M, Giménez A, Gomis R, Mora C.

    J Immunol. 2008 Jan 15;180(2):1189-98.

    PMID:
    18178859
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy.

    Tian C, Ansari MJ, Paez-Cortez J, Bagley J, Godwin J, Donnarumma M, Sayegh MH, Iacomini J.

    J Immunol. 2007 Nov 15;179(10):6762-9.

    PMID:
    17982066
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice.

    Pechhold K, Koczwara K, Zhu X, Harrison VS, Walker G, Lee J, Harlan DM.

    PLoS One. 2009;4(3):e4827. Epub 2009 Mar 16.

    PMID:
    19287497
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Islet expression of M3 uncovers a key role for chemokines in the development and recruitment of diabetogenic cells in NOD mice.

    Martin AP, Grisotto MG, Canasto-Chibuque C, Kunkel SL, Bromberg JS, Furtado GC, Lira SA.

    Diabetes. 2008 Feb;57(2):387-94. Epub 2007 Nov 14.

    PMID:
    18003753
    [PubMed - indexed for MEDLINE]
    Free Article
    16.
    17.

    Type 1 diabetes: chronic progressive autoimmune disease.

    Zhang L, Gianani R, Nakayama M, Liu E, Kobayashi M, Baschal E, Yu L, Babu S, Dawson A, Johnson K, Jahromi M, Aly T, Fain P, Barker J, Rewers M, Eisenbarth GS.

    Novartis Found Symp. 2008;292:85-94; discussion 94-8, 122-9, 202-3.

    PMID:
    19203094
    [PubMed - indexed for MEDLINE]
    18.

    Genetic manipulation of islet cells in autoimmune diabetes: from bench to bedside.

    Chuang YP, Chu CH, Sytwu HK.

    Front Biosci. 2008 May 1;13:6155-69. Review.

    PMID:
    18508650
    [PubMed - indexed for MEDLINE]
    19.

    Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice.

    Zhao Y, Lin B, Darflinger R, Zhang Y, Holterman MJ, Skidgel RA.

    PLoS One. 2009;4(1):e4226. Epub 2009 Jan 19.

    PMID:
    19156219
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.

    Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD.

    Genome Res. 2008 May;18(5):706-16. Epub 2008 Mar 17.

    PMID:
    18347327
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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