PubMed

Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression.

Wang Z, Lecane PS, Thiemann P, Fan Q, Cortez C, Ma X, Tonev D, Miles D, Naumovski L, Miller RA, Magda D, Cho DG, Sessler JL, Pike BL, Yeligar SM, Karaman MW, Hacia JG.

Mol Cancer. 2007 Jan 19;6:9.PMID: 17233922 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor localization and antitumor efficacy of novel sapphyrin compounds.

Naumovski L, Sirisawad M, Lecane P, Chen J, Ramos J, Wang Z, Cortez C, Magda D, Thiemann P, Boswell G, Miles D, Cho DG, Sessler JL, Miller R.

Mol Cancer Ther. 2006 Nov;5(11):2798-805.PMID: 17121926 [PubMed - indexed for MEDLINE]Related articlesFree article

Sapphyrins induce apoptosis in hematopoietic tumor-derived cell lines and show in vivo antitumor activity.

Naumovski L, Ramos J, Sirisawad M, Chen J, Thiemann P, Lecane P, Magda D, Wang Z, Cortez C, Boswell G, Gyu Cho D, Sessler J, Miller R.

Mol Cancer Ther. 2005 Jun;4(6):968-76.PMID: 15956254 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis and anticancer properties of water-soluble zinc ionophores.

Magda D, Lecane P, Wang Z, Hu W, Thiemann P, Ma X, Dranchak PK, Wang X, Lynch V, Wei W, Csokai V, Hacia JG, Sessler JL.

Cancer Res. 2008 Jul 1;68(13):5318-25.PMID: 18593933 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models.

Lee CH, Yao CF, Huang SM, Ko S, Tan YH, Lee-Chen GJ, Wang YC.

Cancer. 2008 Aug 15;113(4):815-25.PMID: 18618576 [PubMed - indexed for MEDLINE]Related articlesFree article

[shRNA-mediated insulin-like growth factor I receptor gene silencing inhibits cell proliferation, induces cell apoptosis, and suppresses tumor growth in non-small cell lung cancer: in vitro and in vivo experiments]

Dong AQ, Kong MJ, Ma ZY, Qian JF, Fan JQ, Xu XH.

Zhonghua Yi Xue Za Zhi. 2007 Jun 5;87(21):1506-9. Chinese. PMID: 17785094 [PubMed - indexed for MEDLINE]Related articles

Combining PCI-24781, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma.

Lopez G, Liu J, Ren W, Wei W, Wang S, Lahat G, Zhu QS, Bornmann WG, McConkey DJ, Pollock RE, Lev DC.

Clin Cancer Res. 2009 May 15;15(10):3472-83. Epub 2009 May 5.PMID: 19417021 [PubMed - indexed for MEDLINE]Related articles

New two-photon activated photodynamic therapy sensitizers induce xenograft tumor regressions after near-IR laser treatment through the body of the host mouse.

Starkey JR, Rebane AK, Drobizhev MA, Meng F, Gong A, Elliott A, McInnerney K, Spangler CW.

Clin Cancer Res. 2008 Oct 15;14(20):6564-73.PMID: 18927297 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression levels of p18INK4C modify the cellular efficacy of cyclin-dependent kinase inhibitors via regulation of Mcl-1 expression in tumor cell lines.

Eguchi T, Itadani H, Shimomura T, Kawanishi N, Hirai H, Kotani H.

Mol Cancer Ther. 2009 Jun;8(6):1460-72. Epub 2009 Jun 9.PMID: 19509251 [PubMed - indexed for MEDLINE]Related articles

Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor.

Mizuarai S, Yamanaka K, Itadani H, Arai T, Nishibata T, Hirai H, Kotani H.

Mol Cancer. 2009 Jun 8;8:34.PMID: 19500427 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin.

Hadaschik BA, Ettinger S, Sowery RD, Zoubeidi A, Andersen RJ, Roberge M, Gleave ME.

Int J Cancer. 2008 May 15;122(10):2368-76.PMID: 18240145 [PubMed - indexed for MEDLINE]Related articles

[Effect of ZGDHu-1 on proliferation and apoptosis of A549 cells in vitro and antitumor activity in vivo]

Zhou YL, Hu WX, Lü YP, Qiu LN, Wang WS, Yang ZY, Liu JD, Rao GW.

Yao Xue Xue Bao. 2007 Jan;42(1):26-34. Chinese. PMID: 17520803 [PubMed - indexed for MEDLINE]Related articles

PCI-24781 induces caspase and reactive oxygen species-dependent apoptosis through NF-kappaB mechanisms and is synergistic with bortezomib in lymphoma cells.

Bhalla S, Balasubramanian S, David K, Sirisawad M, Buggy J, Mauro L, Prachand S, Miller R, Gordon LI, Evens AM.

Clin Cancer Res. 2009 May 15;15(10):3354-65. Epub 2009 May 5. Erratum in: Clin Cancer Res. 2009 Jul 15;15(14):4784-5. PMID: 19417023 [PubMed - indexed for MEDLINE]Related articles

Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen.

Amundson SA, Do KT, Vinikoor LC, Lee RA, Koch-Paiz CA, Ahn J, Reimers M, Chen Y, Scudiero DA, Weinstein JN, Trent JM, Bittner ML, Meltzer PS, Fornace AJ Jr.

Cancer Res. 2008 Jan 15;68(2):415-24.PMID: 18199535 [PubMed - indexed for MEDLINE]Related articlesFree article

Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment.

Schwartz DR, Moin K, Yao B, Matrisian LM, Coussens LM, Bugge TH, Fingleton B, Acuff HB, Sinnamon M, Nassar H, Platts AE, Krawetz SA, Linebaugh BE, Sloane BF.

Mol Cancer Res. 2007 May;5(5):443-54.PMID: 17510311 [PubMed - indexed for MEDLINE]Related articlesFree article

Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer.

Song D, Chaerkady R, Tan AC, García-García E, Nalli A, Suárez-Gauthier A, López-Ríos F, Zhang XF, Solomon A, Tong J, Read M, Fritz C, Jimeno A, Pandey A, Hidalgo M.

Mol Cancer Ther. 2008 Oct;7(10):3275-84.PMID: 18852131 [PubMed - indexed for MEDLINE]Related articlesFree article

D-Serine exposure resulted in gene expression changes indicative of activation of fibrogenic pathways and down-regulation of energy metabolism and oxidative stress response.

Soto A, DelRaso NJ, Schlager JJ, Chan VT.

Toxicology. 2008 Jan 14;243(1-2):177-92. Epub 2007 Oct 23.PMID: 18061331 [PubMed - indexed for MEDLINE]Related articles

Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines.

Lecane PS, Karaman MW, Sirisawad M, Naumovski L, Miller RA, Hacia JG, Magda D.

Cancer Res. 2005 Dec 15;65(24):11676-88.PMID: 16357179 [PubMed - indexed for MEDLINE]Related articlesFree article

Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines.

Magda D, Lecane P, Miller RA, Lepp C, Miles D, Mesfin M, Biaglow JE, Ho VV, Chawannakul D, Nagpal S, Karaman MW, Hacia JG.

Cancer Res. 2005 May 1;65(9):3837-45.PMID: 15867382 [PubMed - indexed for MEDLINE]Related articlesFree article

Suberoylanilide hydroxamic acid (SAHA) changes microRNA expression profiles in A549 human non-small cell lung cancer cells.

Lee EM, Shin S, Cha HJ, Yoon Y, Bae S, Jung JH, Lee SM, Lee SJ, Park IC, Jin YW, An S.

Int J Mol Med. 2009 Jul;24(1):45-50.PMID: 19513533 [PubMed - indexed for MEDLINE]Related articles