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    Results: 1 to 20 of 251

    1.

    Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta-cell sensitivity.

    Ma Z, Portwood N, Brodin D, Grill V, Björklund A.

    Diabetes. 2007 Apr;56(4):1095-106. Epub 2007 Jan 17.PMID: 17229937 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment.

    Yoshikawa H, Ma Z, Björklund A, Grill V.

    Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1202-8. Epub 2004 Aug 3.PMID: 15292032 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets.

    Björklund A, Grill V.

    Diabetes. 1999 Jul;48(7):1409-14.PMID: 10389846 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Glucosamine-induced beta-cell dysfunction: a possible involvement of glucokinase or glucose-transporter type 2.

    Yoshikawa H, Tajiri Y, Sako Y, Hashimato T, Umeda F, Nawata H.

    Pancreas. 2002 Apr;24(3):228-34.PMID: 11893929 [PubMed - indexed for MEDLINE]Related articles

    5.

    Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations.

    Bensellam M, Van Lommel L, Overbergh L, Schuit FC, Jonas JC.

    Diabetologia. 2009 Mar;52(3):463-76. Epub 2009 Jan 23.PMID: 19165461 [PubMed - indexed for MEDLINE]Related articles

    6.

    B-cell insensitivity in vitro: reversal by diazoxide entails more than one event in stimulus-secretion coupling.

    Björklund A, Grill V.

    Endocrinology. 1993 Mar;132(3):1319-28.PMID: 7679978 [PubMed - indexed for MEDLINE]Related articles

    7.

    Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration.

    Jacqueminet S, Briaud I, Rouault C, Reach G, Poitout V.

    Metabolism. 2000 Apr;49(4):532-6.PMID: 10778881 [PubMed - indexed for MEDLINE]Related articles

    8.

    Diazoxide infusion at excess but not at basal hyperglycemia enhances beta-cell sensitivity to glucose in vitro in neonatally streptozotocin-diabetic rats.

    Sako Y, Grill VE.

    Metabolism. 1992 Jul;41(7):738-43.PMID: 1535679 [PubMed - indexed for MEDLINE]Related articles

    9.

    Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

    Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M.

    Diabetologia. 2006 Sep;49(9):2120-30. Epub 2006 Jul 26.PMID: 16868750 [PubMed - indexed for MEDLINE]Related articles

    10.

    Effects of diazoxide on alpha- and beta-cell function in isolated perfused rat pancreas.

    Hirose H, Maruyama H, Ito K, Kido K, Koyama K, Saruta T.

    Diabetes Res Clin Pract. 1994 Sep;25(2):77-82.PMID: 7821194 [PubMed - indexed for MEDLINE]Related articles

    11.

    Appearance of glucose-induced insulin release in fetal rat beta-cells.

    Bergsten P, Aoyagi K, Persson E, Eriksson UJ, Hellerström C.

    J Endocrinol. 1998 Jul;158(1):115-20.PMID: 9713332 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

    Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

    Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.PMID: 17906960 [PubMed - indexed for MEDLINE]Related articles

    13.

    Evidence that insulin secretion influences SNAP-25 through proteasomal activation.

    Ma Z, Portwood N, Foss A, Grill V, Björklund A.

    Biochem Biophys Res Commun. 2005 Apr 15;329(3):1118-26.PMID: 15752769 [PubMed - indexed for MEDLINE]Related articles

    14.

    Glucose-induced [Ca2+]i abnormalities in human pancreatic islets: important role of overstimulation.

    Björklund A, Lansner A, Grill VE.

    Diabetes. 2000 Nov;49(11):1840-8.PMID: 11078450 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

    Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

    Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1beta mediated suppression--possible involvement of the mitochondrial membrane potential.

    Kullin M, Li Z, Bondo Hansen J, Welsh N, Karlsson FA, Sandler S.

    Diabetologia. 2003 Jan;46(1):80-8. Epub 2003 Jan 11.PMID: 12637986 [PubMed - indexed for MEDLINE]Related articles

    17.

    The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets.

    Sasaki N, Iwase M, Uchizono Y, Nakamura U, Imoto H, Abe S, Iida M.

    Diabetologia. 2006 Dec;49(12):2930-8. Epub 2006 Oct 27.PMID: 17072584 [PubMed - indexed for MEDLINE]Related articles

    18.

    Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function.

    Maedler K, Spinas GA, Dyntar D, Moritz W, Kaiser N, Donath MY.

    Diabetes. 2001 Jan;50(1):69-76.PMID: 11147797 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Regulation of insulin secretion and expression of SUR1 gene by chronic exposure to free fatty acids in rat pancreatic beta cells.

    Yuan L, Deng X, Chen L, Zhou M.

    J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):358-60, 364.PMID: 15587398 [PubMed - indexed for MEDLINE]Related articles

    20.

    Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells.

    Ling Z, Kiekens R, Mahler T, Schuit FC, Pipeleers-Marichal M, Sener A, Kloppel G, Malaisse WJ, Pipeleers DG.

    Diabetes. 1996 Dec;45(12):1774-82.PMID: 8922365 [PubMed - indexed for MEDLINE]Related articles

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