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Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra.

Grammatopoulos TN, Jones SM, Ahmadi FA, Hoover BR, Snell LD, Skoch J, Jhaveri VV, Poczobutt AM, Weyhenmeyer JA, Zawada WM.

Mol Neurodegener. 2007 Jan 15;2:1.PMID: 17224059 [PubMed]Related articlesFree article

Potential neuroprotective effect of low dose whole-body gamma-irradiation against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in C57 mice.

Liang Y, Li S, Zou Q, Su B.

Neurosci Lett. 2006 Jun 12;400(3):213-7. Epub 2006 Mar 15.PMID: 16540245 [PubMed - indexed for MEDLINE]Related articles

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Jackson-Lewis V, Jakowec M, Burke RE, Przedborski S.

Neurodegeneration. 1995 Sep;4(3):257-69.PMID: 8581558 [PubMed - indexed for MEDLINE]Related articles

Preventive role of PD-1 on MPTP-induced dopamine depletion in mice.

Jung HW, Son HY, Jin GZ, Park YK.

Cell Biochem Funct. 2010 Feb 23. [Epub ahead of print]PMID: 20186864 [PubMed - as supplied by publisher]Related articles

Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.

Ghosh A, Roy A, Matras J, Brahmachari S, Gendelman HE, Pahan K.

J Neurosci. 2009 Oct 28;29(43):13543-56.PMID: 19864567 [PubMed - indexed for MEDLINE]Related articles

Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra.

Feng ZH, Wang TG, Li DD, Fung P, Wilson BC, Liu B, Ali SF, Langenbach R, Hong JS.

Neurosci Lett. 2002 Sep 6;329(3):354-8.PMID: 12183047 [PubMed - indexed for MEDLINE]Related articles

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

J Neuroinflammation. 2008 May 28;5:21.PMID: 18507839 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease.

Liu LX, Chen WF, Xie JX, Wong MS.

Neurosci Res. 2008 Feb;60(2):156-61. Epub 2007 Oct 23.PMID: 18054104 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death.

Grammatopoulos TN, Ahmadi F, Jones SM, Fariss MW, Weyhenmeyer JA, Zawada WM.

Brain Res. 2005 May 31;1045(1-2):64-71. Epub 2005 Apr 26.PMID: 15910763 [PubMed - indexed for MEDLINE]Related articles

EGb761 protects against nigrostriatal dopaminergic neurotoxicity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice: role of oxidative stress.

Rojas P, Serrano-García N, Mares-Sámano JJ, Medina-Campos ON, Pedraza-Chaverri J, Ogren SO.

Eur J Neurosci. 2008 Jul;28(1):41-50.PMID: 18662333 [PubMed - indexed for MEDLINE]Related articles

Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.

Karunakaran S, Saeed U, Mishra M, Valli RK, Joshi SD, Meka DP, Seth P, Ravindranath V.

J Neurosci. 2008 Nov 19;28(47):12500-9.PMID: 19020042 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.

Zhang D, Anantharam V, Kanthasamy A, Kanthasamy AG.

J Pharmacol Exp Ther. 2007 Sep;322(3):913-22. Epub 2007 Jun 12.PMID: 17565007 [PubMed - indexed for MEDLINE]Related articlesFree article

Tripchlorolide protects against MPTP-induced neurotoxicity in C57BL/6 mice.

Hong Z, Wang G, Gu J, Pan J, Bai L, Zhang S, Chen SD.

Eur J Neurosci. 2007 Sep;26(6):1500-8. Epub 2007 Aug 20.PMID: 17714494 [PubMed - indexed for MEDLINE]Related articles

Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease.

Pattarini R, Smeyne RJ, Morgan JI.

Neuroscience. 2007 Mar 16;145(2):654-68. Epub 2007 Jan 29.PMID: 17258864 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not.

Kreisler A, Gelé P, Wiart JF, Lhermitte M, Destée A, Bordet R.

Brain Res. 2007 Mar 2;1135(1):77-84. Epub 2007 Jan 2.PMID: 17196944 [PubMed - indexed for MEDLINE]Related articles

Estrogen down-regulates glial activation in male mice following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication.

Tripanichkul W, Sripanichkulchai K, Finkelstein DI.

Brain Res. 2006 Apr 21;1084(1):28-37. Epub 2006 Mar 27.PMID: 16564034 [PubMed - indexed for MEDLINE]Related articles

WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

Price DA, Martinez AA, Seillier A, Koek W, Acosta Y, Fernandez E, Strong R, Lutz B, Marsicano G, Roberts JL, Giuffrida A.

Eur J Neurosci. 2009 Jun;29(11):2177-86. Epub 2009 May 21.PMID: 19490092 [PubMed - in process]Related articlesFree article

Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism.

Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL.

J Neurosci. 2009 Nov 11;29(45):14057-65.PMID: 19906954 [PubMed - indexed for MEDLINE]Related articles

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

Singh S, Singh K, Patel DK, Singh C, Nath C, Singh VK, Singh RK, Singh MP.

Rejuvenation Res. 2009 Jun;12(3):185-97.PMID: 19594327 [PubMed - indexed for MEDLINE]Related articles

Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.

Vijitruth R, Liu M, Choi DY, Nguyen XV, Hunter RL, Bing G.

J Neuroinflammation. 2006 Mar 27;3:6.PMID: 16566823 [PubMed]Related articlesFree article