PubMed

SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy.

Barbash O, Lin DI, Diehl JA.

Cell Div. 2007 Jan 15;2:2.PMID: 17224055 [PubMed]Related articlesFree article

Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.

Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, Rustgi A, Fuchs SY, Diehl JA.

Mol Cell. 2006 Nov 3;24(3):355-66.PMID: 17081987 [PubMed - indexed for MEDLINE]Related articlesFree article

SCF(Fbx4/alphaB-crystallin) E3 ligase: when one is not enough.

Barbash O, Diehl JA.

Cell Cycle. 2008 Oct;7(19):2983-6. Epub 2008 Oct 12. Review.PMID: 18818515 [PubMed - indexed for MEDLINE]Related articles

Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation.

Barbash O, Egan E, Pontano LL, Kosak J, Diehl JA.

Oncogene. 2009 Dec 10;28(49):4317-25. Epub .PMID: 19767775 [PubMed - indexed for MEDLINE]Related articles

Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation.

Pontano LL, Diehl JA.

Cell Div. 2008 Sep 2;3:12.PMID: 18764945 [PubMed - in process]Related articlesFree article

alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.

Hu R, Aplin AE.

Pigment Cell Melanoma Res. 2010 Jan 27. [Epub ahead of print]PMID: 20067552 [PubMed - as supplied by publisher]Related articles

Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer.

Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, Lu F, Rustgi AK, Diehl JA.

Cancer Cell. 2008 Jul 8;14(1):68-78.PMID: 18598945 [PubMed - indexed for MEDLINE]Related articlesFree article

The small heat-shock protein alpha B-crystallin promotes FBX4-dependent ubiquitination.

den Engelsman J, Keijsers V, de Jong WW, Boelens WC.

J Biol Chem. 2003 Feb 14;278(7):4699-704. Epub 2002 Dec 4.PMID: 12468532 [PubMed - indexed for MEDLINE]Related articlesFree article

Heat shock factor 1 deficiency via its downstream target gene alphaB-crystallin (Hspb5) impairs p53 degradation.

Jin X, Moskophidis D, Hu Y, Phillips A, Mivechi NF.

J Cell Biochem. 2009 Jun 1;107(3):504-15.PMID: 19343786 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells.

Wei S, Yang HC, Chuang HC, Yang J, Kulp SK, Lu PJ, Lai MD, Chen CS.

J Biol Chem. 2008 Sep 26;283(39):26759-70. Epub 2008 Jul 23.PMID: 18650423 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1.

Jonason JH, Gavrilova N, Wu M, Zhang H, Sun H.

Cell Cycle. 2007 Apr 15;6(8):951-61. Epub 2007 Apr 5.PMID: 17438373 [PubMed - indexed for MEDLINE]Related articles

Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability.

Pontano LL, Aggarwal P, Barbash O, Brown EJ, Bassing CH, Diehl JA.

Mol Cell Biol. 2008 Dec;28(23):7245-58. Epub 2008 Sep 22.PMID: 18809569 [PubMed - indexed for MEDLINE]Related articlesFree article

Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis.

Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA.

Oncogene. 2008 Feb 21;27(9):1231-42. Epub 2007 Aug 27.PMID: 17724472 [PubMed - indexed for MEDLINE]Related articles

Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product.

Elangovan S, Hsieh TC, Wu JM.

Anticancer Res. 2008 Sep-Oct;28(5A):2641-7.PMID: 19035289 [PubMed - indexed for MEDLINE]Related articles

Cyclin D1 degradation is sufficient to induce G1 cell cycle arrest despite constitutive expression of cyclin E2 in ovarian cancer cells.

Masamha CP, Benbrook DM.

Cancer Res. 2009 Aug 15;69(16):6565-72. Epub 2009 Jul 28.PMID: 19638577 [PubMed - indexed for MEDLINE]Related articles

Structural basis of selective ubiquitination of TRF1 by SCFFbx4.

Zeng Z, Wang W, Yang Y, Chen Y, Yang X, Diehl JA, Liu X, Lei M.

Dev Cell. 2010 Feb 16;18(2):214-25.PMID: 20159592 [PubMed - in process]Related articles

Structural basis for the modulation of CDK-dependent/independent activity of cyclin D1.

Ferrer JL, Dupuy J, Borel F, Jacquamet L, Noel JP, Dulic V.

Cell Cycle. 2006 Dec;5(23):2760-8. Epub 2006 Dec 1.PMID: 17172845 [PubMed - indexed for MEDLINE]Related articles

p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells.

Thoms HC, Dunlop MG, Stark LA.

Cancer Res. 2007 Feb 15;67(4):1660-9.PMID: 17308107 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclin D1-cdk4 induce runx2 ubiquitination and degradation.

Shen R, Wang X, Drissi H, Liu F, O'Keefe RJ, Chen D.

J Biol Chem. 2006 Jun 16;281(24):16347-53. Epub 2006 Apr 13.PMID: 16613857 [PubMed - indexed for MEDLINE]Related articlesFree article

Oncostatin M induces growth arrest of skeletal muscle cells in G1 phase by regulating cyclin D1 protein level.

Kim H, Jo C, Jang BG, Oh U, Jo SA.

Cell Signal. 2008 Jan;20(1):120-9. Epub 2007 Oct 3.PMID: 17976956 [PubMed - indexed for MEDLINE]Related articles