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The role of PDGF in radiation oncology.

Li M, Jendrossek V, Belka C.

Radiat Oncol. 2007 Jan 11;2:5. Review.PMID: 17217530 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of action and in vivo role of platelet-derived growth factor.

Heldin CH, Westermark B.

Physiol Rev. 1999 Oct;79(4):1283-316. Review.PMID: 10508235 [PubMed - indexed for MEDLINE]Related articlesFree article

[Platelet- derived growth factor--the construction, role and it's receptors]

Mantur M, Koper O.

Pol Merkur Lekarski. 2008 Feb;24(140):173-6. Review. Polish. PMID: 18634279 [PubMed - indexed for MEDLINE]Related articles

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

Lokker NA, Sullivan CM, Hollenbach SJ, Israel MA, Giese NA.

Cancer Res. 2002 Jul 1;62(13):3729-35.PMID: 12097282 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterisation and application of antibodies specific for the long platelet-derived growth factor A and B chains.

Ostergren-Lundén G, Olivas RG, Eftekhari P, Krettek A, Sanjuan X, Fager G, Vilaró S, Lustig F, Hoebeke J.

Int J Biochem Cell Biol. 2004 Nov;36(11):2226-41.PMID: 15313468 [PubMed - indexed for MEDLINE]Related articles

Regulation of PDGF and its receptors in fibrotic diseases.

Bonner JC.

Cytokine Growth Factor Rev. 2004 Aug;15(4):255-73. Review.PMID: 15207816 [PubMed - indexed for MEDLINE]Related articles

Involvement of platelet-derived growth factor in disease: development of specific antagonists.

Ostman A, Heldin CH.

Adv Cancer Res. 2001;80:1-38. Review.PMID: 11034538 [PubMed - indexed for MEDLINE]Related articles

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury.

Borkham-Kamphorst E, Kovalenko E, van Roeyen CR, Gassler N, Bomble M, Ostendorf T, Floege J, Gressner AM, Weiskirchen R.

Lab Invest. 2008 Oct;88(10):1090-100. Epub 2008 Jul 28.PMID: 18663351 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural and functional aspects of the receptors for platelet-derived growth factor.

Westermark B, Claesson-Welsh L, Heldin CH.

Prog Growth Factor Res. 1989;1(4):253-66. Review.PMID: 2562360 [PubMed - indexed for MEDLINE]Related articles

Small molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells.

Li M, Ping G, Plathow C, Trinh T, Lipson KE, Hauser K, Krempien R, Debus J, Abdollahi A, Huber PE.

BMC Cancer. 2006 Mar 24;6:79.PMID: 16556328 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth-promoting effect of platelet-derived growth factor on rat cardiac myocytes.

Liu J, Wu LL, Li L, Zhang L, Song ZE.

Regul Pept. 2005 Apr 15;127(1-3):11-8.PMID: 15680465 [PubMed - indexed for MEDLINE]Related articles

Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves radiation tumor therapy.

Timke C, Zieher H, Roth A, Hauser K, Lipson KE, Weber KJ, Debus J, Abdollahi A, Huber PE.

Clin Cancer Res. 2008 Apr 1;14(7):2210-9.PMID: 18381963 [PubMed - indexed for MEDLINE]Related articlesFree article

Dependence of autocrine growth factor stimulation in platelet-derived growth factor-B-induced mouse brain tumor cells.

Uhrbom L, Hesselager G, Ostman A, Nistér M, Westermark B.

Int J Cancer. 2000 Feb 1;85(3):398-406.PMID: 10652433 [PubMed - indexed for MEDLINE]Related articles

Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1.

Midgley VC, Khachigian LM.

J Biol Chem. 2004 Sep 24;279(39):40289-95. Epub 2004 Jul 9.PMID: 15247255 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet-derived growth factor signaling and human cancer.

Yu J, Ustach C, Kim HR.

J Biochem Mol Biol. 2003 Jan 31;36(1):49-59. Review.PMID: 12542975 [PubMed - indexed for MEDLINE]Related articlesFree article

Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.

Pietras K, Pahler J, Bergers G, Hanahan D.

PLoS Med. 2008 Jan 29;5(1):e19.PMID: 18232728 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes.

Rosenkranz S, Kazlauskas A.

Growth Factors. 1999;16(3):201-16. Review.PMID: 10372961 [PubMed - indexed for MEDLINE]Related articles

Suppressive effect of taurine on platelet-derived growth factor (PDGF) BB-induced c-fos and c-jun mRNA expressions through extracellular signal-regulated kinase (ERK) in mesenchymal cell lines.

Terashima M, Mitani T, Hosokawa Y, Nariai Y, Imada K, Kageyama E, Tanigawa Y.

J Nutr Sci Vitaminol (Tokyo). 2003 Jun;49(3):187-94.PMID: 12953797 [PubMed - indexed for MEDLINE]Related articles

Targeting PDGF receptors in cancer--rationales and proof of concept clinical trials.

George D.

Adv Exp Med Biol. 2003;532:141-51. Review.PMID: 12908555 [PubMed - indexed for MEDLINE]Related articles

Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migration.

Matsumoto T, Yokote K, Tamura K, Takemoto M, Ueno H, Saito Y, Mori S.

J Biol Chem. 1999 May 14;274(20):13954-60.PMID: 10318806 [PubMed - indexed for MEDLINE]Related articlesFree article