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MAP kinase meets mitosis: a role for Raf Kinase Inhibitory Protein in spindle checkpoint regulation.

Rosner MR.

Cell Div. 2007 Jan 10;2:1.PMID: 17214889 [PubMed]Related articlesFree article

Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint.

Eves EM, Shapiro P, Naik K, Klein UR, Trakul N, Rosner MR.

Mol Cell. 2006 Aug;23(4):561-74.PMID: 16916643 [PubMed - indexed for MEDLINE]Related articlesFree article

B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells.

Cui Y, Guadagno TM.

Oncogene. 2008 May 15;27(22):3122-33. Epub 2007 Dec 10.PMID: 18071315 [PubMed - indexed for MEDLINE]Related articles

Knockdown of B-Raf impairs spindle formation and the mitotic checkpoint in human somatic cells.

Borysova MK, Cui Y, Snyder M, Guadagno TM.

Cell Cycle. 2008 Sep 15;7(18):2894-901. Epub 2008 Sep 26.PMID: 18787396 [PubMed - indexed for MEDLINE]Related articles

Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor.

Granovsky AE, Rosner MR.

Cell Res. 2008 Apr;18(4):452-7. Review.PMID: 18379591 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel role for Cdk1/cyclin B in regulating B-raf activation at mitosis.

Borysov SI, Guadagno TM.

Mol Biol Cell. 2008 Jul;19(7):2907-15. Epub 2008 Apr 23.PMID: 18434602 [PubMed - indexed for MEDLINE]Related articlesFree article

Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability.

Al-Mulla F, Hagan S, Al-Ali W, Jacob SP, Behbehani AI, Bitar MS, Dallol A, Kolch W.

J Clin Pathol. 2008 Apr;61(4):524-9.PMID: 18375747 [PubMed - indexed for MEDLINE]Related articles

Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints.

Knauf JA, Ouyang B, Knudsen ES, Fukasawa K, Babcock G, Fagin JA.

J Biol Chem. 2006 Feb 17;281(7):3800-9. Epub 2005 Nov 29.PMID: 16316983 [PubMed - indexed for MEDLINE]Related articlesFree article

The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK.

Rath O, Park S, Tang HH, Banfield MJ, Brady RL, Lee YC, Dignam JD, Sedivy JM, Kolch W, Yeung KC.

Cell Signal. 2008 May;20(5):935-41. Epub 2008 Jan 24.PMID: 18294816 [PubMed - indexed for MEDLINE]Related articles

Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction.

Klysik J, Theroux SJ, Sedivy JM, Moffit JS, Boekelheide K.

Cell Signal. 2008 Jan;20(1):1-9. Epub 2007 Jul 12. Review.PMID: 17706925 [PubMed - indexed for MEDLINE]Related articlesFree article

Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism.

Granovsky AE, Clark MC, McElheny D, Heil G, Hong J, Liu X, Kim Y, Joachimiak G, Joachimiak A, Koide S, Rosner MR.

Mol Cell Biol. 2009 Mar;29(5):1306-20. Epub 2008 Dec 22.PMID: 19103740 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term ethanol exposure impairs neuronal differentiation of human neuroblastoma cells involving neurotrophin-mediated intracellular signaling and in particular protein kinase C.

Hellmann J, Rommelspacher H, Wernicke C.

Alcohol Clin Exp Res. 2009 Mar;33(3):538-50. Epub 2008 Dec 19.PMID: 19120063 [PubMed - indexed for MEDLINE]Related articles

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7.

Dangi-Garimella S, Yun J, Eves EM, Newman M, Erkeland SJ, Hammond SM, Minn AJ, Rosner MR.

EMBO J. 2009 Feb 18;28(4):347-58. Epub 2009 Jan 15.PMID: 19153603 [PubMed - indexed for MEDLINE]Related articlesFree article

RKIP downregulates B-Raf kinase activity in melanoma cancer cells.

Park S, Yeung ML, Beach S, Shields JM, Yeung KC.

Oncogene. 2005 May 12;24(21):3535-40.PMID: 15782137 [PubMed - indexed for MEDLINE]Related articles

Raf Kinase Inhibitory Protein protects cells against locostatin-mediated inhibition of migration.

Shemon AN, Eves EM, Clark MC, Heil G, Granovsky A, Zeng L, Imamoto A, Koide S, Rosner MR.

PLoS One. 2009 Jun 24;4(6):e6028.PMID: 19551145 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of the MAP kinase signaling cascade by Raf kinase inhibitory protein.

Trakul N, Rosner MR.

Cell Res. 2005 Jan;15(1):19-23. Review.PMID: 15686621 [PubMed - indexed for MEDLINE]Related articlesFree article

G2 and spindle assembly checkpoint adaptation, and tetraploidy arrest: implications for intrinsic and chemically induced genomic instability.

Andreassen PR, Lohez OD, Margolis RL.

Mutat Res. 2003 Nov 27;532(1-2):245-53. Review.PMID: 14643440 [PubMed - indexed for MEDLINE]Related articles

B-Raf is critical for MAPK activation during mitosis and is regulated in an M phase-dependent manner in Xenopus egg extracts.

Borysov SI, Cheng AW, Guadagno TM.

J Biol Chem. 2006 Aug 11;281(32):22586-96. Epub 2006 Jun 8.PMID: 16762920 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling the temporal evolution of the spindle assembly checkpoint and role of Aurora B kinase.

Mistry HB, MacCallum DE, Jackson RC, Chaplain MA, Davidson FA.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20215-20. Epub 2008 Dec 17.PMID: 19091947 [PubMed - indexed for MEDLINE]Related articlesFree article

Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target.

Zeng L, Imamoto A, Rosner MR.

Expert Opin Ther Targets. 2008 Oct;12(10):1275-87. Review.PMID: 18781826 [PubMed - indexed for MEDLINE]Related articles