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SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells.
Goujon C, Rivière L, Jarrosson-Wuilleme L, Bernaud J, Rigal D, Darlix JL, Cimarelli A.
Retrovirology. 2007 Jan 9;4:2.
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The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection.
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Differential apoptosis effects of primate lentiviral Vpr and Vpx in mammalian cells.
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Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).
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Human immunodeficiency virus type 2 vpx protein augments viral infectivity.
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Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.
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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx.
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