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    Results: 1 to 20 of 720

    1.

    Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons.

    Wang QF, Prabhakar S, Chanan S, Cheng JF, Rubin EM, Boffelli D.

    Genome Biol. 2007;8(1):R1.

    PMID:
    17201929
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Close sequence comparisons are sufficient to identify human cis-regulatory elements.

    Prabhakar S, Poulin F, Shoukry M, Afzal V, Rubin EM, Couronne O, Pennacchio LA.

    Genome Res. 2006 Jul;16(7):855-63. Epub 2006 Jun 12.

    PMID:
    16769978
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Phylogenetic shadowing of primate sequences to find functional regions of the human genome.

    Boffelli D, McAuliffe J, Ovcharenko D, Lewis KD, Ovcharenko I, Pachter L, Rubin EM.

    Science. 2003 Feb 28;299(5611):1391-4.

    PMID:
    12610304
    [PubMed - indexed for MEDLINE]
    4.

    Comparative analyses of multi-species sequences from targeted genomic regions.

    Thomas JW, Touchman JW, Blakesley RW, Bouffard GG, Beckstrom-Sternberg SM, Margulies EH, Blanchette M, Siepel AC, Thomas PJ, McDowell JC, Maskeri B, Hansen NF, Schwartz MS, Weber RJ, Kent WJ, Karolchik D, Bruen TC, Bevan R, Cutler DJ, Schwartz S, Elnitski L, Idol JR, Prasad AB, Lee-Lin SQ, Maduro VV, Summers TJ, Portnoy ME, Dietrich NL, Akhter N, Ayele K, Benjamin B, Cariaga K, Brinkley CP, Brooks SY, Granite S, Guan X, Gupta J, Haghighi P, Ho SL, Huang MC, Karlins E, Laric PL, Legaspi R, Lim MJ, Maduro QL, Masiello CA, Mastrian SD, McCloskey JC, Pearson R, Stantripop S, Tiongson EE, Tran JT, Tsurgeon C, Vogt JL, Walker MA, Wetherby KD, Wiggins LS, Young AC, Zhang LH, Osoegawa K, Zhu B, Zhao B, Shu CL, De Jong PJ, Lawrence CE, Smit AF, Chakravarti A, Haussler D, Green P, Miller W, Green ED.

    Nature. 2003 Aug 14;424(6950):788-93.

    PMID:
    12917688
    [PubMed - indexed for MEDLINE]
    5.

    Distribution and intensity of constraint in mammalian genomic sequence.

    Cooper GM, Stone EA, Asimenos G; NISC Comparative Sequencing Program, Green ED, Batzoglou S, Sidow A.

    Genome Res. 2005 Jul;15(7):901-13. Epub 2005 Jun 17.

    PMID:
    15965027
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Evidence for turnover of functional noncoding DNA in mammalian genome evolution.

    Smith NG, Brandström M, Ellegren H.

    Genomics. 2004 Nov;84(5):806-13.

    PMID:
    15475259
    [PubMed - indexed for MEDLINE]
    7.

    Primate-specific evolution of an LDLR enhancer.

    Wang QF, Prabhakar S, Wang Q, Moses AM, Chanan S, Brown M, Eisen MB, Cheng JF, Rubin EM, Boffelli D.

    Genome Biol. 2006;7(8):R68. Epub 2006 Aug 2.

    PMID:
    16884525
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Parallel evolution of conserved non-coding elements that target a common set of developmental regulatory genes from worms to humans.

    Vavouri T, Walter K, Gilks WR, Lehner B, Elgar G.

    Genome Biol. 2007;8(2):R15.

    PMID:
    17274809
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Noncoding sequences conserved in a limited number of mammals in the SIM2 interval are frequently functional.

    Frazer KA, Tao H, Osoegawa K, de Jong PJ, Chen X, Doherty MF, Cox DR.

    Genome Res. 2004 Mar;14(3):367-72. Epub 2004 Feb 12.

    PMID:
    14962988
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Comparative genomics using fugu: a tool for the identification of conserved vertebrate cis-regulatory elements.

    Venkatesh B, Yap WH.

    Bioessays. 2005 Jan;27(1):100-7. Review.

    PMID:
    15612032
    [PubMed - indexed for MEDLINE]
    12.

    SMASHing regulatory sites in DNA by human-mouse sequence comparisons.

    Zavolan M, Socci ND, Rajewsky N, Gaasterlamd T.

    Proc IEEE Comput Soc Bioinform Conf. 2003;2:277-86.

    PMID:
    16452803
    [PubMed - indexed for MEDLINE]
    13.

    Evolutionary discrimination of mammalian conserved non-genic sequences (CNGs).

    Dermitzakis ET, Reymond A, Scamuffa N, Ucla C, Kirkness E, Rossier C, Antonarakis SE.

    Science. 2003 Nov 7;302(5647):1033-5. Epub 2003 Oct 2.

    PMID:
    14526086
    [PubMed - indexed for MEDLINE]
    14.

    Divergence of conserved non-coding sequences: rate estimates and relative rate tests.

    Wagner GP, Fried C, Prohaska SJ, Stadler PF.

    Mol Biol Evol. 2004 Nov;21(11):2116-21. Epub 2004 Jul 28.

    PMID:
    15282332
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Big genomes facilitate the comparative identification of regulatory elements.

    Peterson BK, Hare EE, Iyer VN, Storage S, Conner L, Papaj DR, Kurashima R, Jang E, Eisen MB.

    PLoS One. 2009;4(3):e4688. Epub 2009 Mar 4.

    PMID:
    19259274
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Asymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trend.

    McGaughey DM, Stine ZE, Huynh JL, Vinton RM, McCallion AS.

    BMC Genomics. 2009 Jan 7;10:8.

    PMID:
    19128492
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Functionally conserved cis-regulatory elements of COL18A1 identified through zebrafish transgenesis.

    Kague E, Bessling SL, Lee J, Hu G, Passos-Bueno MR, Fisher S.

    Dev Biol. 2010 Jan 15;337(2):496-505. Epub 2009 Nov 3.

    PMID:
    19895802
    [PubMed - indexed for MEDLINE]
    18.

    Multigenome DNA sequence conservation identifies Hox cis-regulatory elements.

    Kuntz SG, Schwarz EM, DeModena JA, De Buysscher T, Trout D, Shizuya H, Sternberg PW, Wold BJ.

    Genome Res. 2008 Dec;18(12):1955-68. Epub 2008 Nov 3.

    PMID:
    18981268
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Interpreting mammalian evolution using Fugu genome comparisons.

    Ovcharenko I, Stubbs L, Loots GG.

    Genomics. 2004 Nov;84(5):890-5.

    PMID:
    15475268
    [PubMed - indexed for MEDLINE]
    20.

    Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions.

    Bagheri-Fam S, Ferraz C, Demaille J, Scherer G, Pfeifer D.

    Genomics. 2001 Nov;78(1-2):73-82.

    PMID:
    11707075
    [PubMed - indexed for MEDLINE]

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