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Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia.
Vincent JA, Mohr S.
Diabetes. 2007 Jan;56(1):224-30.PMID: 17192486 [PubMed - indexed for MEDLINE]Related articlesFree article
Role of interleukin-1beta in the development of retinopathy in rats: effect of antioxidants.
Kowluru RA, Odenbach S.
Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4161-6.PMID: 15505070 [PubMed - indexed for MEDLINE]Related articlesFree article
Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia.
Kern TS, Tang J, Mizutani M, Kowluru RA, Nagaraj RH, Romeo G, Podesta F, Lorenzi M.
Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3972-8.PMID: 11053301 [PubMed - indexed for MEDLINE]Related articlesFree article
Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy.
Krady JK, Basu A, Allen CM, Xu Y, LaNoue KF, Gardner TW, Levison SW.
Diabetes. 2005 May;54(5):1559-65.PMID: 15855346 [PubMed - indexed for MEDLINE]Related articlesFree article
Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients.
Mohr S, Xi X, Tang J, Kern TS.
Diabetes. 2002 Apr;51(4):1172-9.PMID: 11916941 [PubMed - indexed for MEDLINE]Related articlesFree article
Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes.
Zheng L, Du Y, Miller C, Gubitosi-Klug RA, Ball S, Berkowitz BA, Kern TS.
Diabetologia. 2007 Sep;50(9):1987-96. Epub 2007 Jun 22. Erratum in: Diabetologia. 2007 Oct;50(10):2228. PMID: 17583794 [PubMed - indexed for MEDLINE]Related articles
Comparison of retinal lesions in alloxan-diabetic rats and galactose-fed rats.
Kern TS, Engerman RL.
Curr Eye Res. 1994 Dec;13(12):863-7.PMID: 7720392 [PubMed - indexed for MEDLINE]Related articles
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations.
Joussen AM, Doehmen S, Le ML, Koizumi K, Radetzky S, Krohne TU, Poulaki V, Semkova I, Kociok N.
Mol Vis. 2009 Jul 25;15:1418-28.PMID: 19641635 [PubMed - indexed for MEDLINE]Related articlesFree article
Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy.
Kern TS.
Exp Diabetes Res. 2007;2007:95103. Review.PMID: 18274606 [PubMed - indexed for MEDLINE]Related articlesFree article
Role of interleukin-1beta in the pathogenesis of diabetic retinopathy.
Br J Ophthalmol. 2004 Oct;88(10):1343-7.PMID: 15377563 [PubMed - indexed for MEDLINE]Related articlesFree article
5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.
Gubitosi-Klug RA, Talahalli R, Du Y, Nadler JL, Kern TS.
Diabetes. 2008 May;57(5):1387-93. Epub 2008 Mar 17.PMID: 18346986 [PubMed - indexed for MEDLINE]Related articlesFree article
Topical administration of nepafenac inhibits diabetes-induced retinal microvascular disease and underlying abnormalities of retinal metabolism and physiology.
Kern TS, Miller CM, Du Y, Zheng L, Mohr S, Ball SL, Kim M, Jamison JA, Bingaman DP.
Diabetes. 2007 Feb;56(2):373-9.PMID: 17259381 [PubMed - indexed for MEDLINE]Related articlesFree article
The Ins2Akita mouse as a model of early retinal complications in diabetes.
Barber AJ, Antonetti DA, Kern TS, Reiter CE, Soans RS, Krady JK, Levison SW, Gardner TW, Bronson SK.
Invest Ophthalmol Vis Sci. 2005 Jun;46(6):2210-8.PMID: 15914643 [PubMed - indexed for MEDLINE]Related articlesFree article
Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy.
Kowluru RA, Tang J, Kern TS.
Diabetes. 2001 Aug;50(8):1938-42.PMID: 11473058 [PubMed - indexed for MEDLINE]Related articlesFree article
Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes.
Feit-Leichman RA, Kinouchi R, Takeda M, Fan Z, Mohr S, Kern TS, Chen DF.
Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4281-7.PMID: 16249509 [PubMed - indexed for MEDLINE]Related articlesFree article
Abnormalities of retinal metabolism in diabetes or experimental galactosemia VIII. Prevention by aminoguanidine.
Kowluru RA, Engerman RL, Kern TS.
Curr Eye Res. 2000 Oct;21(4):814-9.PMID: 11120572 [PubMed - indexed for MEDLINE]Related articles
Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes.
Zheng L, Gong B, Hatala DA, Kern TS.
Invest Ophthalmol Vis Sci. 2007 Jan;48(1):361-7.PMID: 17197555 [PubMed - indexed for MEDLINE]Related articlesFree article
Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats.
Diabetes. 2004 Dec;53(12):3233-8.PMID: 15561955 [PubMed - indexed for MEDLINE]Related articlesFree article
Potential new strategies to prevent the development of diabetic retinopathy.
Mohr S.
Expert Opin Investig Drugs. 2004 Mar;13(3):189-98. Review.PMID: 15013939 [PubMed - indexed for MEDLINE]Related articles
Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.
de Gooyer TE, Stevenson KA, Humphries P, Simpson DA, Gardiner TA, Stitt AW.
Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5561-8.PMID: 17122149 [PubMed - indexed for MEDLINE]Related articlesFree article
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