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    Results: 1 to 20 of 121

    1.

    Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells.

    Veluthakal R, Kaur H, Goalstone M, Kowluru A.

    Diabetes. 2007 Jan;56(1):204-10.PMID: 17192483 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation.

    Amin R, Chen HQ, Tannous M, Gibbs R, Kowluru A.

    J Pharmacol Exp Ther. 2002 Oct;303(1):82-8.PMID: 12235236 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.

    Kowluru A.

    J Cell Mol Med. 2008 Jan-Feb;12(1):164-73. Epub 2007 Dec 5. Review.PMID: 18053094 [PubMed - indexed for MEDLINE]Related articles

    4.

    Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells.

    Veluthakal R, Madathilparambil SV, McDonald P, Olson LK, Kowluru A.

    Biochem Pharmacol. 2009 Jan 1;77(1):101-13. Epub 2008 Sep 27.PMID: 18930714 [PubMed - indexed for MEDLINE]Related articles

    5.

    Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins.

    Amin RH, Chen HQ, Veluthakal R, Silver RB, Li J, Li G, Kowluru A.

    Endocrinology. 2003 Oct;144(10):4508-18. Epub 2003 Jun 19.PMID: 12960065 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.

    Kowluru A, Veluthakal R.

    Diabetes. 2005 Dec;54(12):3523-9.PMID: 16306371 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Novel roles for the rho subfamily of GTP-binding proteins in succinate-induced insulin secretion from betaTC3 cells: further evidence in support of the succinate mechanism of insulin release.

    Kowluru A, Chen HQ, Tannous M.

    Endocr Res. 2003 Aug;29(3):363-76.PMID: 14535637 [PubMed - indexed for MEDLINE]Related articles

    8.

    Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.

    Kowluru A, Seavey SE, Li G, Sorenson RL, Weinhaus AJ, Nesher R, Rabaglia ME, Vadakekalam J, Metz SA.

    J Clin Invest. 1996 Jul 15;98(2):540-55.PMID: 8755667 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells.

    Palanivel R, Veluthakal R, Kowluru A.

    Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E1032-41. Epub 2004 Feb 17.PMID: 14970009 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells.

    Li J, Luo R, Kowluru A, Li G.

    Am J Physiol Endocrinol Metab. 2004 May;286(5):E818-27. Epub 2004 Jan 21.PMID: 14736704 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.

    Mulder H, Lu D, Finley J 4th, An J, Cohen J, Antinozzi PA, McGarry JD, Newgard CB.

    J Biol Chem. 2001 Mar 2;276(9):6479-84. Epub 2000 Dec 11.PMID: 11113153 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Biologically active lipids promote trafficking and membrane association of Rac1 in insulin-secreting INS 832/13 cells.

    McDonald P, Veluthakal R, Kaur H, Kowluru A.

    Am J Physiol Cell Physiol. 2007 Mar;292(3):C1216-20. Epub 2006 Oct 11.PMID: 17035298 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

    Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

    Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Effect of PPAR-gamma activation and inhibition on glucose-stimulated insulin release in INS-1e cells.

    Santini E, Fallahi P, Ferrari SM, Masoni A, Antonelli A, Ferrannini E.

    Diabetes. 2004 Dec;53 Suppl 3:S79-83.PMID: 15561927 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: evidence for functional consequences on enzyme activity and insulin secretion.

    Kowluru A, Seavey SE, Rabaglia ME, Nesher R, Metz SA.

    Endocrinology. 1996 Jun;137(6):2315-23.PMID: 8641181 [PubMed - indexed for MEDLINE]Related articles

    16.

    Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion.

    Kowluru A.

    Biochem Pharmacol. 2002 Jun 15;63(12):2091-100.PMID: 12110368 [PubMed - indexed for MEDLINE]Related articles

    17.

    Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential.

    Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P.

    Int J Biochem Cell Biol. 2008;40(8):1522-35. Epub 2007 Dec 3.PMID: 18248766 [PubMed - indexed for MEDLINE]Related articles

    18.

    Depletion of the catalytic subunit of protein phosphatase-2A (PP2Ac) markedly attenuates glucose-stimulated insulin secretion in pancreatic beta-cells.

    Jangati GR, Veluthakal R, Susick L, Gruber SA, Kowluru A.

    Endocrine. 2007 Jun;31(3):248-53.PMID: 17906371 [PubMed - indexed for MEDLINE]Related articles

    19.

    Ca v 1.3 is preferentially coupled to glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.

    Liu G, Dilmac N, Hilliard N, Hockerman GH.

    J Pharmacol Exp Ther. 2003 Apr;305(1):271-8.PMID: 12649379 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate.

    Sun Y, Zhang L, Gu HF, Han W, Ren M, Wang F, Gong B, Wang L, Guo H, Xin W, Zhao J, Gao L.

    Endocrinology. 2008 Feb;149(2):662-71. Epub 2007 Nov 8.PMID: 17991720 [PubMed - indexed for MEDLINE]Related articlesFree article

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