PubMed

Peroxisome proliferator-activated receptor-gamma regulates expression of PDX-1 and NKX6.1 in INS-1 cells.

Moibi JA, Gupta D, Jetton TL, Peshavaria M, Desai R, Leahy JL.

Diabetes. 2007 Jan;56(1):88-95.PMID: 17192469 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate.

Sun Y, Zhang L, Gu HF, Han W, Ren M, Wang F, Gong B, Wang L, Guo H, Xin W, Zhao J, Gao L.

Endocrinology. 2008 Feb;149(2):662-71. Epub 2007 Nov 8.PMID: 17991720 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse pdx-1 promoter.

Gupta D, Jetton TL, Mortensen RM, Duan SZ, Peshavaria M, Leahy JL.

J Biol Chem. 2008 Nov 21;283(47):32462-70. Epub 2008 Aug 21.PMID: 18718916 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.

Ravnskjaer K, Boergesen M, Rubi B, Larsen JK, Nielsen T, Fridriksson J, Maechler P, Mandrup S.

Endocrinology. 2005 Aug;146(8):3266-76. Epub 2005 May 5.PMID: 15878969 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.

Kim EK, Kwon KB, Koo BS, Han MJ, Song MY, Song EK, Han MK, Park JW, Ryu DG, Park BH.

Int J Biochem Cell Biol. 2007;39(6):1260-75. Epub 2007 Apr 19.PMID: 17521952 [PubMed - indexed for MEDLINE]Related articles

Reduced insulin, GLUT2, and IDX-1 in beta-cells after partial pancreatectomy.

Zangen DH, Bonner-Weir S, Lee CH, Latimer JB, Miller CP, Habener JF, Weir GC.

Diabetes. 1997 Feb;46(2):258-64.PMID: 9000703 [PubMed - indexed for MEDLINE]Related articles

PDX-1 expression and proliferation of duct epithelial cells after partial pancreatectomy in rats.

Liu T, Wang CY, Gou SM, Wu HS, Xiong JX, Zhou J.

Hepatobiliary Pancreat Dis Int. 2007 Aug;6(4):424-9.PMID: 17690043 [PubMed - indexed for MEDLINE]Related articlesFree article

PDX-1 expression is associated with islet proliferation in vitro and in vivo.

Feanny MA, Fagan SP, Ballian N, Liu SH, Li Z, Wang X, Fisher W, Brunicardi FC, Belaguli NS.

J Surg Res. 2008 Jan;144(1):8-16. Epub 2007 Jun 20.PMID: 17583748 [PubMed - indexed for MEDLINE]Related articles

The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration.

Sharma A, Zangen DH, Reitz P, Taneja M, Lissauer ME, Miller CP, Weir GC, Habener JF, Bonner-Weir S.

Diabetes. 1999 Mar;48(3):507-13.PMID: 10078550 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal homeobox.

Yoshikawa H, Tajiri Y, Sako Y, Hashimoto T, Umeda F, Nawata H.

Metabolism. 2001 May;50(5):613-8.PMID: 11319727 [PubMed - indexed for MEDLINE]Related articles

Maturation of adult beta-cells revealed using a Pdx1/insulin dual-reporter lentivirus.

Szabat M, Luciani DS, Piret JM, Johnson JD.

Endocrinology. 2009 Apr;150(4):1627-35. Epub 2008 Dec 18.PMID: 19095744 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells.

Zhang X, Sun N, Wang L, Guo H, Guan Q, Cui B, Tian L, Gao L, Zhao J.

J Cell Mol Med. 2009 Apr;13(4):758-70.PMID: 19438972 [PubMed - indexed for MEDLINE]Related articles

Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells.

Zheng S, Chen A.

Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G113-23. Epub 2006 Sep 7.PMID: 16959952 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity.

Nielsen K, Kruhøffer M, Orntoft T, Sparre T, Wang H, Wollheim C, Jørgensen MC, Nerup J, Karlsen AE.

Diabetologia. 2004 Dec;47(12):2185-99. Epub 2004 Dec 17.PMID: 15605246 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure.

Evans-Molina C, Robbins RD, Kono T, Tersey SA, Vestermark GL, Nunemaker CS, Garmey JC, Deering TG, Keller SR, Maier B, Mirmira RG.

Mol Cell Biol. 2009 Apr;29(8):2053-67. Epub 2009 Feb 23.PMID: 19237535 [PubMed - indexed for MEDLINE]Related articlesFree article

BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells.

Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M.

Diabetologia. 2006 Oct;49(10):2350-8. Epub 2006 Aug 5.PMID: 16896941 [PubMed - indexed for MEDLINE]Related articles

Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.

Wang H, Iezzi M, Theander S, Antinozzi PA, Gauthier BR, Halban PA, Wollheim CB.

Diabetologia. 2005 Apr;48(4):720-31. Epub 2005 Mar 9.PMID: 15756539 [PubMed - indexed for MEDLINE]Related articles

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.

Schisler JC, Jensen PB, Taylor DG, Becker TC, Knop FK, Takekawa S, German M, Weir GC, Lu D, Mirmira RG, Newgard CB.

Proc Natl Acad Sci U S A. 2005 May 17;102(20):7297-302. Epub 2005 May 9.PMID: 15883383 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of PPAR-gamma activation and inhibition on glucose-stimulated insulin release in INS-1e cells.

Santini E, Fallahi P, Ferrari SM, Masoni A, Antonelli A, Ferrannini E.

Diabetes. 2004 Dec;53 Suppl 3:S79-83.PMID: 15561927 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells.

Cheng Y, Ping J, Xu LM.

Chin Med J (Engl). 2007 May 5;120(9):794-801.PMID: 17531121 [PubMed - indexed for MEDLINE]Related articlesFree article