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    Results: 1 to 20 of 334

    1.

    Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

    Ritzel RA, Meier JJ, Lin CY, Veldhuis JD, Butler PC.

    Diabetes. 2007 Jan;56(1):65-71.PMID: 17192466 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Replication increases beta-cell vulnerability to human islet amyloid polypeptide-induced apoptosis.

    Ritzel RA, Butler PC.

    Diabetes. 2003 Jul;52(7):1701-8.PMID: 12829636 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Activation of peroxisome proliferator-activated receptor-gamma by rosiglitazone protects human islet cells against human islet amyloid polypeptide toxicity by a phosphatidylinositol 3'-kinase-dependent pathway.

    Lin CY, Gurlo T, Haataja L, Hsueh WA, Butler PC.

    J Clin Endocrinol Metab. 2005 Dec;90(12):6678-86. Epub 2005 Oct 4.PMID: 16204373 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice.

    Lin CY, Gurlo T, Kayed R, Butler AE, Haataja L, Glabe CG, Butler PC.

    Diabetes. 2007 May;56(5):1324-32. Epub 2007 Mar 12.PMID: 17353506 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP.

    Meier JJ, Kayed R, Lin CY, Gurlo T, Haataja L, Jayasinghe S, Langen R, Glabe CG, Butler PC.

    Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1317-24. Epub 2006 Jul 18.PMID: 16849627 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Influence of islet amyloid polypeptide and the 8-37 fragment of islet amyloid polypeptide on insulin release from perifused rat islets.

    Wang ZL, Bennet WM, Ghatei MA, Byfield PG, Smith DM, Bloom SR.

    Diabetes. 1993 Feb;42(2):330-5.PMID: 8425669 [PubMed - indexed for MEDLINE]Related articles

    8.

    Islet amyloid polypeptide regulates multiple steps in stimulus-secretion coupling of beta cells in rat pancreatic islets.

    Wang F, Permert J, Ostenson CG.

    Pancreas. 2000 Apr;20(3):264-9.PMID: 10766452 [PubMed - indexed for MEDLINE]Related articles

    10.

    Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.

    Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC.

    Diabetes. 2004 Jun;53(6):1509-16.PMID: 15161755 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Islet amyloid polypeptide in the islets of Langerhans: friend or foe?

    Gebre-Medhin S, Olofsson C, Mulder H.

    Diabetologia. 2000 Jun;43(6):687-95. Review.PMID: 10907112 [PubMed - indexed for MEDLINE]Related articles

    12.

    Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.

    Matveyenko AV, Butler PC.

    ILAR J. 2006;47(3):225-33. Review.PMID: 16804197 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Islet amyloid polypeptide (IAPP) secretion from pancreatic islets isolated from non-obese diabetic (NOD) mice.

    Karlsson E, Stridsberg M, Sandler S.

    Regul Pept. 1996 May 7;63(1):39-45.PMID: 8795087 [PubMed - indexed for MEDLINE]Related articles

    14.

    Islet amyloid, islet-amyloid polypeptide, and diabetes mellitus.

    Johnson KH, O'Brien TD, Betsholtz C, Westermark P.

    N Engl J Med. 1989 Aug 24;321(8):513-8. Review.PMID: 2668761 [PubMed - indexed for MEDLINE]Related articles

    15.

    The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.

    Verchere CB, D'Alessio DA, Prigeon RL, Hull RL, Kahn SE.

    Diabetes. 2000 Sep;49(9):1477-84.PMID: 10969831 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Effects of islet amyloid polypeptide (IAPP) on insulin biosynthesis or secretion in rat islets and mouse beta TC3 cells. Biosynthesis of IAPP in mouse beta TC3 cells.

    Nagamatsu S, Nishi M, Steiner DF.

    Diabetes Res Clin Pract. 1992 Jan;15(1):49-55.PMID: 1541235 [PubMed - indexed for MEDLINE]Related articles

    17.

    Expression of human islet amyloid polypeptide/amylin impairs insulin secretion in mouse pancreatic beta cells.

    Tokuyama T, Yagui K, Yamaguchi T, Huang CI, Kuramoto N, Shimada F, Miyazaki J, Horie H, Saito Y, Makino H, Kanatsuka A.

    Metabolism. 1997 Sep;46(9):1044-51.PMID: 9284894 [PubMed - indexed for MEDLINE]Related articles

    18.

    Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.

    Matveyenko AV, Gurlo T, Daval M, Butler AE, Butler PC.

    Diabetes. 2009 Apr;58(4):906-16. Epub 2009 Jan 16.PMID: 19151199 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Newly identified pancreatic protein islet amyloid polypeptide. What is its relationship to diabetes?

    Johnson KH, O'Brien TD, Westermark P.

    Diabetes. 1991 Mar;40(3):310-4. Review.PMID: 1999270 [PubMed - indexed for MEDLINE]Related articles

    20.

    Islet amyloid polypeptide inhibits glucose-stimulated insulin secretion from isolated rat pancreatic islets.

    Ohsawa H, Kanatsuka A, Yamaguchi T, Makino H, Yoshida S.

    Biochem Biophys Res Commun. 1989 Apr 28;160(2):961-7.PMID: 2655598 [PubMed - indexed for MEDLINE]Related articles

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