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    Results: 1 to 20 of 225

    1.

    Crystal structure of the major diabetes autoantigen insulinoma-associated protein 2 reveals distinctive immune epitopes.

    Kim SJ, Jeong DG, Jeong SK, Yoon TS, Ryu SE.

    Diabetes. 2007 Jan;56(1):41-8.PMID: 17192463 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mapping of novel autoreactive epitopes of the diabetes-associated autoantigen IA-2.

    Seissler J, Schott M, Morgenthaler NG, Scherbaum WA.

    Clin Exp Immunol. 2000 Nov;122(2):157-63.PMID: 11091269 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Human monoclonal antibodies isolated from type I diabetes patients define multiple epitopes in the protein tyrosine phosphatase-like IA-2 antigen.

    Kolm-Litty V, Berlo S, Bonifacio E, Bearzatto M, Engel AM, Christie M, Ziegler AG, Wild T, Endl J.

    J Immunol. 2000 Oct 15;165(8):4676-84.PMID: 11035111 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents.

    Honeyman MC, Stone NL, Harrison LC.

    Mol Med. 1998 Apr;4(4):231-9.PMID: 9606176 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    IA-2 (islet cell antigen 512) is the primary target of humoral autoimmunity against type 1 diabetes-associated tyrosine phosphatase autoantigens.

    Bonifacio E, Lampasona V, Bingley PJ.

    J Immunol. 1998 Sep 1;161(5):2648-54.PMID: 9725268 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.

    Diez J, Park Y, Zeller M, Brown D, Garza D, Ricordi C, Hutton J, Eisenbarth GS, Pugliese A.

    Diabetes. 2001 Apr;50(4):895-900.PMID: 11289059 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Engineering and expression of the intracellular domain of insulinoma-associated tyrosine phosphatase (IA-2ic), a type 1 diabetes autoantigen, in plants.

    Mett V, Shamloul AM, Hirai H, Zhou Z, Notkins A, Yusibov V.

    Transgenic Res. 2007 Feb;16(1):77-84. Epub 2006 Nov 11.PMID: 17103024 [PubMed - indexed for MEDLINE]Related articles

    8.

    Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.

    Bearzatto M, Naserke H, Piquer S, Koczwara K, Lampasona V, Williams A, Christie MR, Bingley PJ, Ziegler AG, Bonifacio E.

    J Immunol. 2002 Apr 15;168(8):4202-8.PMID: 11937581 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.

    Cui L, Yu WP, DeAizpurua HJ, Schmidli RS, Pallen CJ.

    J Biol Chem. 1996 Oct 4;271(40):24817-23.PMID: 8798755 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4.

    Peakman M, Stevens EJ, Lohmann T, Narendran P, Dromey J, Alexander A, Tomlinson AJ, Trucco M, Gorga JC, Chicz RM.

    J Clin Invest. 1999 Nov;104(10):1449-57.PMID: 10562307 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Enterovirus infection may induce humoral immune response reacting with islet cell autoantigens in humans.

    Härkönen T, Paananen A, Lankinen H, Hovi T, Vaarala O, Roivainen M.

    J Med Virol. 2003 Mar;69(3):426-40.PMID: 12526055 [PubMed - indexed for MEDLINE]Related articles

    12.

    Detection of proteolytic cleavages of diabetes-associated protein IA-2 beta in the pancreas and the brain using novel anti-IA-2 beta monoclonal antibodies.

    Kawakami T, Saeki K, Takeyama N, Wu G, Sakudo A, Matsumoto Y, Hayashi T, Onodera T.

    Int J Mol Med. 2007 Aug;20(2):177-85.PMID: 17611635 [PubMed - indexed for MEDLINE]Related articles

    13.

    Fine mapping of diabetes-associated IA-2 specific autoantibodies.

    Bearzatto M, Lampasona V, Belloni C, Bonifacio E.

    J Autoimmun. 2003 Dec;21(4):377-82.PMID: 14624760 [PubMed - indexed for MEDLINE]Related articles

    14.

    Expression and physicochemical characterization of an extracellular segment of the receptor protein tyrosine phosphatase IA-2.

    Primo ME, Sica MP, Risso VA, Poskus E, Ermácora MR.

    Biochim Biophys Acta. 2006 Feb;1764(2):174-81. Epub 2005 Dec 27.PMID: 16413232 [PubMed - indexed for MEDLINE]Related articles

    15.

    Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes.

    Kawasaki E, Hutton JC, Eisenbarth GS.

    Biochem Biophys Res Commun. 1996 Oct 14;227(2):440-7.PMID: 8878534 [PubMed - indexed for MEDLINE]Related articles

    16.

    IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm.

    Zahn TR, Macmorris MA, Dong W, Day R, Hutton JC.

    J Comp Neurol. 2001 Jan 1;429(1):127-43.PMID: 11086294 [PubMed - indexed for MEDLINE]Related articles

    17.

    Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

    Kubosaki A, Gross S, Miura J, Saeki K, Zhu M, Nakamura S, Hendriks W, Notkins AL.

    Diabetes. 2004 Jul;53(7):1684-91.PMID: 15220191 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients.

    Blancou P, Mallone R, Martinuzzi E, Sévère S, Pogu S, Novelli G, Bruno G, Charbonnel B, Dolz M, Chaillous L, van Endert P, Bach JM.

    J Immunol. 2007 Jun 1;178(11):7458-66.PMID: 17513797 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Characterization and chromosomal localization of PTP-NP-2, a new isoform of protein tyrosine phosphatase-like receptor, expressed on synaptic boutons.

    Jiang S, Tulloch AG, Kim TA, Fu Y, Rogers R, Gaskell A, White RA, Avraham H, Avraham S.

    Gene. 1998 Jul 30;215(2):345-59.PMID: 9714834 [PubMed - indexed for MEDLINE]Related articles

    20.

    ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies.

    Miao D, Yu L, Tiberti C, Cuthbertson DD, Rewers M, di Mario U, Eisenbarth GS, Dotta F.

    J Autoimmun. 2002 Mar;18(2):191-6.PMID: 11908951 [PubMed - indexed for MEDLINE]Related articles

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