PubMed

Recombinant activated factor VII as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy: subgroup analysis from two randomized trials.

Rizoli SB, Boffard KD, Riou B, Warren B, Iau P, Kluger Y, Rossaint R, Tillinger M; NovoSeven Trauma Study Group.

Crit Care. 2006;10(6):R178.PMID: 17184516 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials.

Boffard KD, Riou B, Warren B, Choong PI, Rizoli S, Rossaint R, Axelsen M, Kluger Y; NovoSeven Trauma Study Group.

J Trauma. 2005 Jul;59(1):8-15; discussion 15-8.PMID: 16096533 [PubMed - indexed for MEDLINE]Related articles

Early versus late recombinant factor VIIa in combat trauma patients requiring massive transfusion.

Perkins JG, Schreiber MA, Wade CE, Holcomb JB.

J Trauma. 2007 May;62(5):1095-9; discussion 1099-101.PMID: 17495707 [PubMed - indexed for MEDLINE]Related articles

Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial.

Kluger Y, Riou B, Rossaint R, Rizoli SB, Boffard KD, Choong PI, Warren B, Tillinger M.

Crit Care. 2007;11(4):R85.PMID: 17686152 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant activated coagulation factor VII and bleeding trauma patients.

Rizoli SB, Nascimento B Jr, Osman F, Netto FS, Kiss A, Callum J, Brenneman FD, Tremblay L, Tien HC.

J Trauma. 2006 Dec;61(6):1419-25.PMID: 17159685 [PubMed - indexed for MEDLINE]Related articles

Recombinant activated factor VII for coagulopathy in fulminant hepatic failure compared with conventional therapy.

Shami VM, Caldwell SH, Hespenheide EE, Arseneau KO, Bickston SJ, Macik BG.

Liver Transpl. 2003 Feb;9(2):138-43.PMID: 12548507 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of coagulopathy in critically ill patients with traumatic brain injury: recombinant factor VIIa is more cost-effective than plasma.

Stein DM, Dutton RP, Kramer ME, Scalea TM.

J Trauma. 2009 Jan;66(1):63-72; discussion 73-5.PMID: 19131807 [PubMed - indexed for MEDLINE]Related articles

Low-dose recombinant factor VIIa for trauma patients with coagulopathy.

Stein DM, Dutton RP, Hess JR, Scalea TM.

Injury. 2008 Sep;39(9):1054-61. Epub 2008 Jul 25.PMID: 18656871 [PubMed - indexed for MEDLINE]Related articles

The clinical and laboratory response to recombinant factor VIIA in trauma and surgical patients with acquired coagulopathy.

McMullin NR, Kauvar DS, Currier HM, Baskin TW, Pusateri AE, Holcomb JB.

Curr Surg. 2006 Jul-Aug;63(4):246-51.PMID: 16843774 [PubMed - indexed for MEDLINE]Related articles

[Activated recombinant factor VII (Novoseven) in multiple trauma patients: an outcome analysis]

Grinţescu I, Tulbure D, Mirea L.

Chirurgia (Bucur). 2006 Nov-Dec;101(6):615-24. Romanian. PMID: 17283837 [PubMed - indexed for MEDLINE]Related articles

Recombinant activated factor VII for the rapid correction of coagulopathy in nonhemophilic neurosurgical patients.

Park P, Fewel ME, Garton HJ, Thompson BG, Hoff JT.

Neurosurgery. 2003 Jul;53(1):34-8; discussion 38-9.PMID: 12823871 [PubMed - indexed for MEDLINE]Related articles

Recombinant activated factor VIIa use in massive transfusion and coagulopathy unresponsive to conventional therapy.

Gowers CJ, Parr MJ.

Anaesth Intensive Care. 2005 Apr;33(2):196-200.PMID: 15960401 [PubMed - indexed for MEDLINE]Related articles

Use of recombinant factor VIIa for adjunctive hemorrhage control in trauma and surgical patients.

Benharash P, Bongard F, Putnam B.

Am Surg. 2005 Sep;71(9):776-80.PMID: 16468517 [PubMed - indexed for MEDLINE]Related articles

A multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial assessing safety and efficacy of active site inactivated recombinant factor VIIa in subjects with acute lung injury or acute respiratory distress syndrome.

Vincent JL, Artigas A, Petersen LC, Meyer C.

Crit Care Med. 2009 Jun;37(6):1874-80.PMID: 19384216 [PubMed - indexed for MEDLINE]Related articles

Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuries.

Martinowitz U, Holcomb JB, Pusateri AE, Stein M, Onaca N, Freidman M, Macaitis JM, Castel D, Hedner U, Hess JR.

J Trauma. 2001 Apr;50(4):721-9.PMID: 11303171 [PubMed - indexed for MEDLINE]Related articles

The role of recombinant factor VIIa in the treatment of life-threatening haemorrhage in blunt trauma.

Geeraedts LM Jr, Kamphuisen PW, Kaasjager HA, Verwiel JM, van Vugt AB, Frölke JP.

Injury. 2005 Apr;36(4):495-500. Epub 2004 Dec 8.PMID: 15755430 [PubMed - indexed for MEDLINE]Related articles

The effect of recombinant activated factor VII on mortality in combat-related casualties with severe trauma and massive transfusion.

Spinella PC, Perkins JG, McLaughlin DF, Niles SE, Grathwohl KW, Beekley AC, Salinas J, Mehta S, Wade CE, Holcomb JB.

J Trauma. 2008 Feb;64(2):286-93; discussion 293-4.PMID: 18301188 [PubMed - indexed for MEDLINE]Related articles

The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries.

Schreiber MA, Holcomb JB, Hedner U, Brundage SI, Macaitis JM, Hoots K.

J Trauma. 2002 Aug;53(2):252-7; discussion 257-9.PMID: 12169930 [PubMed - indexed for MEDLINE]Related articles

Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial.

Bosch J, Thabut D, Bendtsen F, D'Amico G, Albillos A, González Abraldes J, Fabricius S, Erhardtsen E, de Franchis R; European Study Group on rFVIIa in UGI Haemorrhage.

Gastroenterology. 2004 Oct;127(4):1123-30.PMID: 15480990 [PubMed - indexed for MEDLINE]Related articles

Control of bleeding in children with Dengue hemorrhagic fever using recombinant activated factor VII: a randomized, double-blind, placebo-controlled study.

Chuansumrit A, Wangruangsatid S, Lektrakul Y, Chua MN, Zeta Capeding MR, Bech OM; Dengue Study Group.

Blood Coagul Fibrinolysis. 2005 Nov;16(8):549-55.PMID: 16269927 [PubMed - indexed for MEDLINE]Related articles