PubMed

TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs.

McLeod RL, Fernandez X, Correll CC, Phelps TP, Jia Y, Wang X, Hey JA.

Cough. 2006 Dec 15;2:10.PMID: 17173683 [PubMed]Related articlesFree article

Cloning and pharmacological characterization of mouse TRPV1.

Correll CC, Phelps PT, Anthes JC, Umland S, Greenfeder S.

Neurosci Lett. 2004 Nov 3;370(1):55-60.PMID: 15489017 [PubMed - indexed for MEDLINE]Related articles

Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs.

Bhattacharya A, Scott BP, Nasser N, Ao H, Maher MP, Dubin AE, Swanson DM, Shankley NP, Wickenden AD, Chaplan SR.

J Pharmacol Exp Ther. 2007 Nov;323(2):665-74. Epub 2007 Aug 9.PMID: 17690251 [PubMed - indexed for MEDLINE]Related articlesFree article

Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1.

Gavva NR, Tamir R, Klionsky L, Norman MH, Louis JC, Wild KD, Treanor JJ.

Mol Pharmacol. 2005 Dec;68(6):1524-33. Epub 2005 Aug 31.PMID: 16135784 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfur-dioxide exposure increases TRPV1-mediated responses in nodose ganglia cells and augments cough in guinea pigs.

McLeod RL, Jia Y, McHugh NA, Fernandez X, Mingo GG, Wang X, Parra LE, Chen J, Brown D, Bolser DC, Kreutner W, Hey JA.

Pulm Pharmacol Ther. 2007;20(6):750-7. Epub 2006 Oct 10.PMID: 17126052 [PubMed - indexed for MEDLINE]Related articles

TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats.

De Schepper HU, De Man JG, Ruyssers NE, Deiteren A, Van Nassauw L, Timmermans JP, Martinet W, Herman AG, Pelckmans PA, De Winter BY.

Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G245-53. Epub 2007 Nov 8.PMID: 17991707 [PubMed - indexed for MEDLINE]Related articlesFree article

Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.

McLeod RL, Jia Y, Fernandez X, Parra LE, Wang X, Tulshian DB, Kiselgof EJ, Tan Z, Fawzi AB, Smith-Torhan A, Zhang H, Hey JA.

Pharmacology. 2004 Jul;71(3):143-9.PMID: 15161996 [PubMed - indexed for MEDLINE]Related articles

N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.

Valenzano KJ, Grant ER, Wu G, Hachicha M, Schmid L, Tafesse L, Sun Q, Rotshteyn Y, Francis J, Limberis J, Malik S, Whittemore ER, Hodges D.

J Pharmacol Exp Ther. 2003 Jul;306(1):377-86. Epub 2003 Apr 29.PMID: 12721338 [PubMed - indexed for MEDLINE]Related articlesFree article

N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflammatory and neuropathic pain.

Pomonis JD, Harrison JE, Mark L, Bristol DR, Valenzano KJ, Walker K.

J Pharmacol Exp Ther. 2003 Jul;306(1):387-93. Epub 2003 Apr 29.PMID: 12721336 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of increased cough sensitivity after antigen challenge in guinea pigs.

Liu Q, Fujimura M, Tachibana H, Myou S, Kasahara K, Yasui M.

Clin Exp Allergy. 2001 Mar;31(3):474-84.PMID: 11260161 [PubMed - indexed for MEDLINE]Related articles

Functional study on TRPV1-mediated signalling in the mouse small intestine: involvement of tachykinin receptors.

de Man JG, Boeckx S, Anguille S, de Winter BY, de Schepper HU, Herman AG, Pelckmans PA.

Neurogastroenterol Motil. 2008 May;20(5):546-56. Epub 2008 Jan 13.PMID: 18194153 [PubMed - indexed for MEDLINE]Related articles

Inhibition of citric acid- and capsaicin-induced cough by novel TRPV-1 antagonist, V112220, in guinea-pig.

Leung SY, Niimi A, Williams AS, Nath P, Blanc FX, Dinh QT, Chung KF.

Cough. 2007 Dec 23;3:10.PMID: 18154688 [PubMed - in process]Related articlesFree article

Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs.

Gatti R, Andre E, Amadesi S, Dinh TQ, Fischer A, Bunnett NW, Harrison S, Geppetti P, Trevisani M.

J Appl Physiol. 2006 Aug;101(2):506-11. Epub 2006 Apr 20.PMID: 16627674 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor.

Gunthorpe MJ, Hannan SL, Smart D, Jerman JC, Arpino S, Smith GD, Brough S, Wright J, Egerton J, Lappin SC, Holland VA, Winborn K, Thompson M, Rami HK, Randall A, Davis JB.

J Pharmacol Exp Ther. 2007 Jun;321(3):1183-92. Epub 2007 Mar 28.PMID: 17392405 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of cough reflex sensitivity after an inhaled antigen challenge between actively and passively sensitized guinea pigs.

Hara J, Fujimura M, Myou S, Oribe Y, Furusho S, Kita T, Katayama N, Abo M, Ohkura N, Herai Y, Hori A, Ishiura Y, Nobata K, Ogawa H, Yasui M, Kasahara K, Nakao S.

Cough. 2005 Sep 6;1:6.PMID: 16270933 [PubMed]Related articlesFree article

Cloning and functional characterization of dog transient receptor potential vanilloid receptor-1 (TRPV1).

Phelps PT, Anthes JC, Correll CC.

Eur J Pharmacol. 2005 Apr 18;513(1-2):57-66. Epub 2005 Apr 13.PMID: 15878709 [PubMed - indexed for MEDLINE]Related articles

The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder.

Saitoh C, Kitada C, Uchida W, Chancellor MB, de Groat WC, Yoshimura N.

Eur J Pharmacol. 2007 Sep 10;570(1-3):182-7. Epub 2007 Jun 5.PMID: 17586490 [PubMed - indexed for MEDLINE]Related articlesFree article

[The effect of bradykinin B(2) receptor antagonist on cough reactivity in a sensitized guinea pig model]

Qiu Z, Liu Q, Guo D, Fu X.

Zhonghua Jie He He Hu Xi Za Zhi. 2002 Feb;25(2):74-7. Chinese. PMID: 11953101 [PubMed - indexed for MEDLINE]Related articles

Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs.

Oribe Y, Fujimura M, Kita T, Katayama N, Nishitsuji M, Hara J, Myou S, Nakao S.

Clin Exp Allergy. 2005 Mar;35(3):262-7.PMID: 15784101 [PubMed - indexed for MEDLINE]Related articles

Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia.

Kanai Y, Hara T, Imai A, Sakakibara A.

J Pharm Pharmacol. 2007 May;59(5):733-8.PMID: 17524240 [PubMed - indexed for MEDLINE]Related articles