PubMed

Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury.

Looney MR, Matthay MA.

Crit Care. 2006;10(6):239. Review.PMID: 17169139 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant human activated protein C: a system modulator of vascular function for treatment of severe sepsis.

Grinnell BW, Joyce D.

Crit Care Med. 2001 Jul;29(7 Suppl):S53-60; discussion S60-1. Review.PMID: 11445735 [PubMed - indexed for MEDLINE]Related articles

Activated protein C versus protein C in severe sepsis.

Yan SB, Dhainaut JF.

Crit Care Med. 2001 Jul;29(7 Suppl):S69-74. Review.PMID: 11445737 [PubMed - indexed for MEDLINE]Related articles

Leukocyte and endothelial cell interactions in sepsis: relevance of the protein C pathway.

Joyce DE, Nelson DR, Grinnell BW.

Crit Care Med. 2004 May;32(5 Suppl):S280-6. Review.PMID: 15118531 [PubMed - indexed for MEDLINE]Related articles

[Mechanisms of action of recombinant human activated Protein C]

Brueckmann M, Huhle G, Max M.

Anaesthesist. 2006 Jun;55 Suppl 1:5-15. Review. German. PMID: 16520928 [PubMed - indexed for MEDLINE]Related articles

Activated protein C: potential therapy for severe sepsis, thrombosis, and stroke.

Griffin JH, Zlokovic B, Fernández JA.

Semin Hematol. 2002 Jul;39(3):197-205. Review.PMID: 12124682 [PubMed - indexed for MEDLINE]Related articles

Activated protein C--an anticoagulant that does more than stop clots.

Jackson CJ, Xue M.

Int J Biochem Cell Biol. 2008;40(12):2692-7. Epub 2008 Jan 3. Review.PMID: 18249579 [PubMed - indexed for MEDLINE]Related articles

Signal transduction induced by activated protein C: no role in protection against sepsis?

Slofstra SH, ten Cate H, Spek CA.

Trends Mol Med. 2006 Aug;12(8):374-81. Epub 2006 Jul 3. Review.PMID: 16820322 [PubMed - indexed for MEDLINE]Related articles

Endogenous protein C activation in patients with severe sepsis.

Liaw PC.

Crit Care Med. 2004 May;32(5 Suppl):S214-8. Review.PMID: 15118520 [PubMed - indexed for MEDLINE]Related articles

New therapeutic applications for the anticoagulant, activated protein C.

Jackson C, Whitmont K, Tritton S, March L, Sambrook P, Xue M.

Expert Opin Biol Ther. 2008 Aug;8(8):1109-22. Review.PMID: 18613763 [PubMed - indexed for MEDLINE]Related articles

Benefit-risk assessment of drotrecogin alfa (activated) in the treatment of sepsis.

De Backer D.

Drug Saf. 2007;30(11):995-1010. Review.PMID: 17973539 [PubMed - indexed for MEDLINE]Related articles

[The numerous properties of the anticoagulant protein C]

Cerchiara E, Tirindelli MC, Giannetti B, Dicuonzo G, Avvisati G.

Clin Ter. 2007 Mar-Apr;158(2):181-7. Review. Italian. PMID: 17566522 [PubMed - indexed for MEDLINE]Related articles

Activated protein C and sepsis.

O'Brien LA, Gupta A, Grinnell BW.

Front Biosci. 2006 Jan 1;11:676-98. Review.PMID: 16146761 [PubMed - indexed for MEDLINE]Related articles

Natural anticoagulant inhibitors: activated Protein C.

Aird WC.

Best Pract Res Clin Haematol. 2004 Mar;17(1):161-82. Review.PMID: 15171965 [PubMed - indexed for MEDLINE]Related articles

New thoughts on sepsis: the unifier of critical care.

Schulman CS, Hare K.

Dimens Crit Care Nurs. 2003 Jan-Feb;22(1):20-30. Review.PMID: 12548098 [PubMed - indexed for MEDLINE]Related articles

The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome.

Aird WC.

Blood. 2003 May 15;101(10):3765-77. Epub 2003 Jan 23. Review.PMID: 12543869 [PubMed - indexed for MEDLINE]Related articlesFree article

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H.

J Exp Med. 2007 Oct 1;204(10):2439-48. Epub 2007 Sep 24.PMID: 17893198 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective mechanisms of activated protein C in severe inflammatory disorders.

Neyrinck AP, Liu KD, Howard JP, Matthay MA.

Br J Pharmacol. 2009 Oct;158(4):1034-47. Epub 2009 May 14.PMID: 19466992 [PubMed - in process]Related articles

[Protein C and coagulation in sepsis]

D'Angelo A, Della Valle P, Giudici D, Viganò D'Angelo S.

Minerva Anestesiol. 2004 May;70(5):339-50. Review. Italian. PMID: 15181414 [PubMed - indexed for MEDLINE]Related articlesFree article

The cytoprotective protein C pathway.

Mosnier LO, Zlokovic BV, Griffin JH.

Blood. 2007 Apr 15;109(8):3161-72. Epub 2006 Nov 16. Review.PMID: 17110453 [PubMed - indexed for MEDLINE]Related articlesFree article