PubMed

Fatty acid signaling in the beta-cell and insulin secretion.

Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M.

Diabetes. 2006 Dec;55 Suppl 2:S16-23. Review.PMID: 17130640 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.

Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M.

Diabetes. 2004 Apr;53(4):1007-19.PMID: 15047616 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.

Corkey BE, Deeney JT, Yaney GC, Tornheim K, Prentki M.

J Nutr. 2000 Feb;130(2S Suppl):299S-304S. Review.PMID: 10721892 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights into fatty acid modulation of pancreatic beta-cell function.

Haber EP, Procópio J, Carvalho CR, Carpinelli AR, Newsholme P, Curi R.

Int Rev Cytol. 2006;248:1-41. Review.PMID: 16487789 [PubMed - indexed for MEDLINE]Related articles

Pleiotropic effects of fatty acids on pancreatic beta-cells.

Haber EP, Ximenes HM, Procópio J, Carvalho CR, Curi R, Carpinelli AR.

J Cell Physiol. 2003 Jan;194(1):1-12. Review.PMID: 12447984 [PubMed - indexed for MEDLINE]Related articles

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M.

Diabetologia. 2006 Sep;49(9):2120-30. Epub 2006 Jul 26.PMID: 16868750 [PubMed - indexed for MEDLINE]Related articles

Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.

Komatsu M, Yajima H, Yamada S, Kaneko T, Sato Y, Yamauchi K, Hashizume K, Aizawa T.

Diabetes. 1999 Aug;48(8):1543-9.PMID: 10426371 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.

Brun T, Roche E, Assimacopoulos-Jeannet F, Corkey BE, Kim KH, Prentki M.

Diabetes. 1996 Feb;45(2):190-8.PMID: 8549864 [PubMed - indexed for MEDLINE]Related articles

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion.

Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, Corkey BE.

J Biol Chem. 1992 Mar 25;267(9):5802-10.PMID: 1556096 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid metabolism and insulin secretion in pancreatic beta cells.

Yaney GC, Corkey BE.

Diabetologia. 2003 Oct;46(10):1297-312. Epub 2003 Sep 12. Review.PMID: 13680127 [PubMed - indexed for MEDLINE]Related articles

Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.

Schnell S, Schaefer M, Schöfl C.

Mol Cell Endocrinol. 2007 Jan 15;263(1-2):173-80. Epub 2006 Nov 13.PMID: 17101212 [PubMed - indexed for MEDLINE]Related articles

A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells.

Corkey BE, Glennon MC, Chen KS, Deeney JT, Matschinsky FM, Prentki M.

J Biol Chem. 1989 Dec 25;264(36):21608-12.PMID: 2689441 [PubMed - indexed for MEDLINE]Related articlesFree article

A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.

Skelly RH, Bollheimer LC, Wicksteed BL, Corkey BE, Rhodes CJ.

Biochem J. 1998 Apr 15;331 ( Pt 2):553-61.PMID: 9531497 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

Antinozzi PA, Segall L, Prentki M, McGarry JD, Newgard CB.

J Biol Chem. 1998 Jun 26;273(26):16146-54.PMID: 9632669 [PubMed - indexed for MEDLINE]Related articlesFree article

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release.

Fujiwara K, Maekawa F, Yada T.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E670-7. Epub 2005 May 24.PMID: 15914509 [PubMed - indexed for MEDLINE]Related articlesFree article

Malonyl-CoA, fuel sensing, and insulin resistance.

Ruderman NB, Saha AK, Vavvas D, Witters LA.

Am J Physiol. 1999 Jan;276(1 Pt 1):E1-E18. Review.PMID: 9886945 [PubMed - indexed for MEDLINE]Related articlesFree article

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

Prentki M, Corkey BE.

Diabetes. 1996 Mar;45(3):273-83. Review.PMID: 8593930 [PubMed - indexed for MEDLINE]Related articles

Glucose-stimulated signaling pathways in biphasic insulin secretion.

Straub SG, Sharp GW.

Diabetes Metab Res Rev. 2002 Nov-Dec;18(6):451-63. Review.PMID: 12469359 [PubMed - indexed for MEDLINE]Related articles

Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes.

Hu L, Deeney JT, Nolan CJ, Peyot ML, Ao A, Richard AM, Luc E, Faergeman NJ, Knudsen J, Guo W, Sorhede-Winzell M, Prentki M, Corkey BE.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1085-92. Epub 2005 Aug 9.PMID: 16091387 [PubMed - indexed for MEDLINE]Related articlesFree article