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    Results: 1 to 20 of 492

    1.

    Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance.

    Dezaki K, Sone H, Koizumi M, Nakata M, Kakei M, Nagai H, Hosoda H, Kangawa K, Yada T.

    Diabetes. 2006 Dec;55(12):3486-93.PMID: 17130496 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents.

    Dezaki K, Hosoda H, Kakei M, Hashiguchi S, Watanabe M, Kangawa K, Yada T.

    Diabetes. 2004 Dec;53(12):3142-51.PMID: 15561944 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis.

    Dezaki K, Sone H, Yada T.

    Pharmacol Ther. 2008 May;118(2):239-49. Epub 2008 Mar 10. Review.PMID: 18433874 [PubMed - indexed for MEDLINE]Related articles

    4.

    Ghrelin regulates insulin release and glycemia: physiological role and therapeutic potential.

    Yada T, Dezaki K, Sone H, Koizumi M, Damdindorj B, Nakata M, Kakei M.

    Curr Diabetes Rev. 2008 Feb;4(1):18-23. Review.PMID: 18220691 [PubMed - indexed for MEDLINE]Related articles

    5.

    Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin.

    Dezaki K, Kakei M, Yada T.

    Diabetes. 2007 Sep;56(9):2319-27. Epub 2007 Jun 15.PMID: 17575083 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.

    Salehi A, Dornonville de la Cour C, Håkanson R, Lundquist I.

    Regul Pept. 2004 May 15;118(3):143-50.PMID: 15003830 [PubMed - indexed for MEDLINE]Related articles

    7.

    [The effects of electric stress on pancreatic B cell function in rats fed a high fat diet (I). Glucose tolerance and glucose-induced insulin release from the perfused pancreas (author's transl)]

    Yamaguchi K, Matsuoka A.

    Nippon Naibunpi Gakkai Zasshi. 1979 Dec 20;55(12):1469-81. Japanese. PMID: 397067 [PubMed - indexed for MEDLINE]Related articles

    8.

    IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.

    Doi A, Shono T, Nishi M, Furuta H, Sasaki H, Nanjo K.

    Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):885-90. Epub 2006 Jan 17.PMID: 16418280 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice.

    Tan CP, Feng Y, Zhou YP, Eiermann GJ, Petrov A, Zhou C, Lin S, Salituro G, Meinke P, Mosley R, Akiyama TE, Einstein M, Kumar S, Berger JP, Mills SG, Thornberry NA, Yang L, Howard AD.

    Diabetes. 2008 Aug;57(8):2211-9. Epub 2008 May 13.PMID: 18477808 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice.

    Iwakura H, Hosoda K, Son C, Fujikura J, Tomita T, Noguchi M, Ariyasu H, Takaya K, Masuzaki H, Ogawa Y, Hayashi T, Inoue G, Akamizu T, Hosoda H, Kojima M, Itoh H, Toyokuni S, Kangawa K, Nakao K.

    J Biol Chem. 2005 Apr 15;280(15):15247-56. Epub 2005 Feb 8.PMID: 15701644 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.

    Sun Y, Wang P, Zheng H, Smith RG.

    Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4679-84. Epub 2004 Mar 18.PMID: 15070777 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion.

    Date Y, Nakazato M, Hashiguchi S, Dezaki K, Mondal MS, Hosoda H, Kojima M, Kangawa K, Arima T, Matsuo H, Yada T, Matsukura S.

    Diabetes. 2002 Jan;51(1):124-9.PMID: 11756331 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice.

    Imai Y, Patel HR, Hawkins EJ, Doliba NM, Matschinsky FM, Ahima RS.

    Endocrinology. 2007 Dec;148(12):5716-23. Epub 2007 Aug 23.PMID: 17717054 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion.

    Fujino T, Asaba H, Kang MJ, Ikeda Y, Sone H, Takada S, Kim DH, Ioka RX, Ono M, Tomoyori H, Okubo M, Murase T, Kamataki A, Yamamoto J, Magoori K, Takahashi S, Miyamoto Y, Oishi H, Nose M, Okazaki M, Usui S, Imaizumi K, Yanagisawa M, Sakai J, Yamamoto TT.

    Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):229-34. Epub 2002 Dec 30.PMID: 12509515 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.

    Guerre-Millo M, Rouault C, Poulain P, André J, Poitout V, Peters JM, Gonzalez FJ, Fruchart JC, Reach G, Staels B.

    Diabetes. 2001 Dec;50(12):2809-14.PMID: 11723064 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The effects of intrauterine undernutrition on pancreas ghrelin and insulin expression in neonate rats.

    Wang X, Liang L, Du L.

    J Endocrinol. 2007 Jul;194(1):121-9.PMID: 17592026 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Islet perturbations in rats fed a high-fat diet.

    Ahrén B, Gudbjartsson T, Al-Amin AN, Mårtensson H, Myrsén-Axcrona U, Karlsson S, Mulder H, Sundler F.

    Pancreas. 1999 Jan;18(1):75-83.PMID: 9888663 [PubMed - indexed for MEDLINE]Related articles

    18.

    GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice.

    Bonaventura MM, Catalano PN, Chamson-Reig A, Arany E, Hill D, Bettler B, Saravia F, Libertun C, Lux-Lantos VA.

    Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E157-67. Epub 2007 Oct 30.PMID: 17971510 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice.

    Winzell MS, Magnusson C, Ahrén B.

    Metabolism. 2007 Jan;56(1):122-8.PMID: 17161234 [PubMed - indexed for MEDLINE]Related articles

    20.

    Increased glucose tolerance in N-type Ca2+ channel alpha(1B)-subunit gene-deficient mice.

    Takahashi E, Ito M, Miyamoto N, Nagasu T, Ino M, Tanaka I.

    Int J Mol Med. 2005 Jun;15(6):937-44.PMID: 15870896 [PubMed - indexed for MEDLINE]Related articles

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