PubMed

Lipin deficiency impairs diurnal metabolic fuel switching.

Xu J, Lee WN, Phan J, Saad MF, Reue K, Kurland IJ.

Diabetes. 2006 Dec;55(12):3429-38.PMID: 17130489 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene.

Reue K, Xu P, Wang XP, Slavin BG.

J Lipid Res. 2000 Jul;41(7):1067-76.PMID: 10884287 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin.

Péterfy M, Phan J, Xu P, Reue K.

Nat Genet. 2001 Jan;27(1):121-4.PMID: 11138012 [PubMed - indexed for MEDLINE]Related articles

Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion.

Chen Z, Gropler MC, Norris J, Lawrence JC Jr, Harris TE, Finck BN.

Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1738-44. Epub 2008 Jul 31.PMID: 18669885 [PubMed - indexed for MEDLINE]Related articlesFree article

Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.

Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K.

J Biol Chem. 2007 Feb 9;282(6):3450-7. Epub 2006 Dec 7.PMID: 17158099 [PubMed - indexed for MEDLINE]Related articlesFree article

Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice.

Herrema H, Derks TG, van Dijk TH, Bloks VW, Gerding A, Havinga R, Tietge UJ, Müller M, Smit GP, Kuipers F, Reijngoud DJ.

Hepatology. 2008 Jun;47(6):1894-904.PMID: 18459129 [PubMed - indexed for MEDLINE]Related articles

The fatty liver dystrophy mutant mouse: microvesicular steatosis associated with altered expression levels of peroxisome proliferator-regulated proteins.

Rehnmark S, Giometti CS, Slavin BG, Doolittle MH, Reue K.

J Lipid Res. 1998 Nov;39(11):2209-17.PMID: 9799807 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.

Gropler MC, Harris TE, Hall AM, Wolins NE, Gross RW, Han X, Chen Z, Finck BN.

J Biol Chem. 2009 Mar 13;284(11):6763-72. Epub 2009 Jan 10.PMID: 19136718 [PubMed - indexed for MEDLINE]Related articles

Investigation of in vivo fatty acid metabolism in AFABP/aP2(-/-) mice.

Baar RA, Dingfelder CS, Smith LA, Bernlohr DA, Wu C, Lange AJ, Parks EJ.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E187-93. Epub 2004 Sep 14.PMID: 15367400 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced adipose tissue triglyceride synthesis and increased muscle fatty acid oxidation in C5L2 knockout mice.

Paglialunga S, Schrauwen P, Roy C, Moonen-Kornips E, Lu H, Hesselink MK, Deshaies Y, Richard D, Cianflone K.

J Endocrinol. 2007 Aug;194(2):293-304.PMID: 17641279 [PubMed - indexed for MEDLINE]Related articlesFree article

Shift in metabolic fuel in acylation-stimulating protein-deficient mice following a high-fat diet.

Roy C, Paglialunga S, Fisette A, Schrauwen P, Moonen-Kornips E, St-Onge J, Hesselink MK, Richard D, Joanisse DR, Cianflone K.

Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1051-9. Epub 2008 Apr 8.PMID: 18398012 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered gene expression pattern in the fatty liver dystrophy mouse reveals impaired insulin-mediated cytoskeleton dynamics.

Klingenspor M, Xu P, Cohen RD, Welch C, Reue K.

J Biol Chem. 1999 Aug 13;274(33):23078-84.PMID: 10438476 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipin, a lipodystrophy and obesity gene.

Phan J, Reue K.

Cell Metab. 2005 Jan;1(1):73-83.PMID: 16054046 [PubMed - indexed for MEDLINE]Related articles

Alterations in carbohydrate metabolism and its regulation in PPARalpha null mouse hearts.

Gélinas R, Labarthe F, Bouchard B, Mc Duff J, Charron G, Young ME, Des Rosiers C.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1571-80. Epub 2008 Jan 25.PMID: 18223187 [PubMed - indexed for MEDLINE]Related articlesFree article

Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation.

Li JZ, Ye J, Xue B, Qi J, Zhang J, Zhou Z, Li Q, Wen Z, Li P.

Diabetes. 2007 Oct;56(10):2523-32. Epub 2007 Jul 23.PMID: 17646209 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse.

Xu J, Gowen L, Raphalides C, Hoyer KK, Weinger JG, Renard M, Troke JJ, Vaitheesyaran B, Lee WN, Saad MF, Sleeman MW, Teitell MA, Kurland IJ.

Diabetes. 2006 Dec;55(12):3372-80.PMID: 17130482 [PubMed - indexed for MEDLINE]Related articlesFree article

Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition.

Singh V, Grötzinger C, Nowak KW, Zacharias S, Göncz E, Pless G, Sauer IM, Eichhorn I, Pfeiffer-Guglielmi B, Hamprecht B, Wiedenmann B, Plöckinger U, Strowski MZ.

Endocrinology. 2007 Aug;148(8):3887-99. Epub 2007 May 24.PMID: 17525126 [PubMed - indexed for MEDLINE]Related articlesFree article

Carbohydrate-response element-binding protein deletion alters substrate utilization producing an energy-deficient liver.

Burgess SC, Iizuka K, Jeoung NH, Harris RA, Kashiwaya Y, Veech RL, Kitazume T, Uyeda K.

J Biol Chem. 2008 Jan 18;283(3):1670-8. Epub 2007 Nov 27.PMID: 18042547 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver.

Rasooly R, Kelley DS, Greg J, Mackey BE.

Br J Nutr. 2007 Jan;97(1):58-66.PMID: 17217560 [PubMed - indexed for MEDLINE]Related articles

The role of lipin 1 in adipogenesis and lipid metabolism.

Reue K.

Novartis Found Symp. 2007;286:58-68; discussion 68-71, 162-3, 196-203.PMID: 18269174 [PubMed - indexed for MEDLINE]Related articles