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    Results: 1 to 20 of 134

    1.

    Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse.

    Xu J, Gowen L, Raphalides C, Hoyer KK, Weinger JG, Renard M, Troke JJ, Vaitheesyaran B, Lee WN, Saad MF, Sleeman MW, Teitell MA, Kurland IJ.

    Diabetes. 2006 Dec;55(12):3372-80.PMID: 17130482 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production.

    Xu J, Xiao G, Trujillo C, Chang V, Blanco L, Joseph SB, Bassilian S, Saad MF, Tontonoz P, Lee WN, Kurland IJ.

    J Biol Chem. 2002 Dec 27;277(52):50237-44. Epub 2002 Aug 9.PMID: 12176975 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity.

    Wong JT, Kim PT, Peacock JW, Yau TY, Mui AL, Chung SW, Sossi V, Doudet D, Green D, Ruth TJ, Parsons R, Verchere CB, Ong CJ.

    Diabetologia. 2007 Feb;50(2):395-403. Epub 2006 Dec 29.PMID: 17195063 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1.

    Okamoto Y, Ogawa W, Nishizawa A, Inoue H, Teshigawara K, Kinoshita S, Matsuki Y, Watanabe E, Hiramatsu R, Sakaue H, Noda T, Kasuga M.

    Diabetes. 2007 Apr;56(4):1000-9. Epub 2007 Jan 31.PMID: 17267763 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.

    Kushner JA, Simpson L, Wartschow LM, Guo S, Rankin MM, Parsons R, White MF.

    J Biol Chem. 2005 Nov 25;280(47):39388-93. Epub 2005 Sep 16.PMID: 16170201 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux.

    Xu J, Chang V, Joseph SB, Trujillo C, Bassilian S, Saad MF, Lee WN, Kurland IJ.

    Endocrinology. 2004 Mar;145(3):1087-95. Epub 2003 Dec 11.PMID: 14670991 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance.

    Ferre T, Riu E, Franckhauser S, Agudo J, Bosch F.

    Diabetologia. 2003 Dec;46(12):1662-8. Epub 2003 Nov 12.PMID: 14614559 [PubMed - indexed for MEDLINE]Related articles

    8.

    Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels and reduced body weight.

    Hariharan N, Farrelly D, Hagan D, Hillyer D, Arbeeny C, Sabrah T, Treloar A, Brown K, Kalinowski S, Mookhtiar K.

    Diabetes. 1997 Jan;46(1):11-6.PMID: 8971074 [PubMed - indexed for MEDLINE]Related articles

    9.

    Perturbation of glucose flux in the liver by decreasing F26P2 levels causes hepatic insulin resistance and hyperglycemia.

    Wu C, Khan SA, Peng LJ, Li H, Carmella SG, Lange AJ.

    Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E536-43. Epub 2006 Apr 18. Erratum in: Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E370. PMID: 16621898 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice.

    Fukui K, Wada T, Kagawa S, Nagira K, Ikubo M, Ishihara H, Kobayashi M, Sasaoka T.

    Diabetes. 2005 Jul;54(7):1958-67.PMID: 15983195 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism.

    Niswender KD, Shiota M, Postic C, Cherrington AD, Magnuson MA.

    J Biol Chem. 1997 Sep 5;272(36):22570-5.PMID: 9278411 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Normalization of prandial blood glucose and improvement of glucose tolerance by liver-specific inhibition of SH2 domain containing inositol phosphatase 2 (SHIP2) in diabetic KKAy mice: SHIP2 inhibition causes insulin-mimetic effects on glycogen metabolism, gluconeogenesis, and glycolysis.

    Grempler R, Zibrova D, Schoelch C, van Marle A, Rippmann JF, Redemann N.

    Diabetes. 2007 Sep;56(9):2235-41. Epub 2007 Jun 27.PMID: 17596404 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The lack of beta-adrenoceptors results in enhanced insulin sensitivity in mice exhibiting increased adiposity and glucose intolerance.

    Asensio C, Jimenez M, Kühne F, Rohner-Jeanrenaud F, Muzzin P.

    Diabetes. 2005 Dec;54(12):3490-5.PMID: 16306366 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice.

    Kagawa S, Soeda Y, Ishihara H, Oya T, Sasahara M, Yaguchi S, Oshita R, Wada T, Tsuneki H, Sasaoka T.

    Endocrinology. 2008 Feb;149(2):642-50. Epub 2007 Nov 26.PMID: 18039790 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Hypoglycemia with enhanced hepatic glycogen synthesis in recombinant mice lacking hexose-6-phosphate dehydrogenase.

    Lavery GG, Hauton D, Hewitt KN, Brice SM, Sherlock M, Walker EA, Stewart PM.

    Endocrinology. 2007 Dec;148(12):6100-6. Epub 2007 Sep 6.PMID: 17823265 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance.

    Zinker B, Mika A, Nguyen P, Wilcox D, Ohman L, von Geldern TW, Opgenorth T, Jacobson P.

    Metabolism. 2007 Mar;56(3):380-7.PMID: 17292727 [PubMed - indexed for MEDLINE]Related articles

    17.

    Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice.

    Herrema H, Derks TG, van Dijk TH, Bloks VW, Gerding A, Havinga R, Tietge UJ, Müller M, Smit GP, Kuipers F, Reijngoud DJ.

    Hepatology. 2008 Jun;47(6):1894-904.PMID: 18459129 [PubMed - indexed for MEDLINE]Related articles

    18.

    Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action.

    Samuel VT, Choi CS, Phillips TG, Romanelli AJ, Geisler JG, Bhanot S, McKay R, Monia B, Shutter JR, Lindberg RA, Shulman GI, Veniant MM.

    Diabetes. 2006 Jul;55(7):2042-50.PMID: 16804074 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver.

    Jackerott M, Baudry A, Bucchini D, Jami J, Joshi RL.

    Diabetologia. 2002 Sep;45(9):1292-7. Epub 2002 Jul 31.PMID: 12242462 [PubMed - indexed for MEDLINE]Related articles

    20.

    Txnip balances metabolic and growth signaling via PTEN disulfide reduction.

    Hui ST, Andres AM, Miller AK, Spann NJ, Potter DW, Post NM, Chen AZ, Sachithanantham S, Jung DY, Kim JK, Davis RA.

    Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3921-6. Epub 2008 Mar 5.PMID: 18322014 [PubMed - indexed for MEDLINE]Related articlesFree article

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