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    Results: 1 to 20 of 336

    1.

    Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency.

    Clodfelder-Miller BJ, Zmijewska AA, Johnson GV, Jope RS.

    Diabetes. 2006 Dec;55(12):3320-5.PMID: 17130475 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease.

    Yanagisawa M, Planel E, Ishiguro K, Fujita SC.

    FEBS Lett. 1999 Nov 19;461(3):329-33.PMID: 10567721 [PubMed - indexed for MEDLINE]Related articles

    3.

    Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms.

    Planel E, Tatebayashi Y, Miyasaka T, Liu L, Wang L, Herman M, Yu WH, Luchsinger JA, Wadzinski B, Duff KE, Takashima A.

    J Neurosci. 2007 Dec 12;27(50):13635-48.PMID: 18077675 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease.

    Gong CX, Lidsky T, Wegiel J, Zuck L, Grundke-Iqbal I, Iqbal K.

    J Biol Chem. 2000 Feb 25;275(8):5535-44.PMID: 10681533 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Stress-induced hyperphosphorylation of tau in the mouse brain.

    Okawa Y, Ishiguro K, Fujita SC.

    FEBS Lett. 2003 Jan 30;535(1-3):183-9.PMID: 12560101 [PubMed - indexed for MEDLINE]Related articles

    6.

    Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.

    Freude S, Plum L, Schnitker J, Leeser U, Udelhoven M, Krone W, Bruning JC, Schubert M.

    Diabetes. 2005 Dec;54(12):3343-8.PMID: 16306348 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse.

    Planel E, Yasutake K, Fujita SC, Ishiguro K.

    J Biol Chem. 2001 Sep 7;276(36):34298-306. Epub 2001 Jul 5.PMID: 11441005 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.

    Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX.

    Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10804-9. Epub 2004 Jul 12.PMID: 15249677 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin.

    Jolivalt CG, Lee CA, Beiswenger KK, Smith JL, Orlov M, Torrance MA, Masliah E.

    J Neurosci Res. 2008 Nov 15;86(15):3265-74.PMID: 18627032 [PubMed - indexed for MEDLINE]Related articles

    10.

    Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease.

    Liu F, Shi J, Tanimukai H, Gu J, Gu J, Grundke-Iqbal I, Iqbal K, Gong CX.

    Brain. 2009 Jul;132(Pt 7):1820-32. Epub 2009 May 18.PMID: 19451179 [PubMed - indexed for MEDLINE]Related articles

    11.

    Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.

    Padmanabhan J, Levy M, Dickson DW, Potter H.

    Brain. 2006 Nov;129(Pt 11):3020-34. Epub 2006 Sep 20.PMID: 16987932 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease.

    Planel E, Miyasaka T, Launey T, Chui DH, Tanemura K, Sato S, Murayama O, Ishiguro K, Tatebayashi Y, Takashima A.

    J Neurosci. 2004 Mar 10;24(10):2401-11.PMID: 15014115 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Site-specific regulation of Alzheimer-like tau phosphorylation in living neurons.

    Burack MA, Halpain S.

    Neuroscience. 1996 May;72(1):167-84.PMID: 8730715 [PubMed - indexed for MEDLINE]Related articles

    14.

    Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications.

    Deutsch SI, Rosse RB, Lakshman RM.

    Prog Neuropsychopharmacol Biol Psychiatry. 2006 Dec 30;30(8):1369-80. Epub 2006 Jun 21. Review.PMID: 16793187 [PubMed - indexed for MEDLINE]Related articles

    15.

    Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A.

    Gong CX, Grundke-Iqbal I, Iqbal K.

    Neuroscience. 1994 Aug;61(4):765-72.PMID: 7838376 [PubMed - indexed for MEDLINE]Related articles

    16.

    Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain.

    Gong CX, Lidsky T, Wegiel J, Grundke-Iqbal I, Iqbal K.

    Brain Res Brain Res Protoc. 2001 Feb;6(3):134-40.PMID: 11223412 [PubMed - indexed for MEDLINE]Related articles

    17.

    Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration.

    Wang JZ, Grundke-Iqbal I, Iqbal K.

    Eur J Neurosci. 2007 Jan;25(1):59-68.PMID: 17241267 [PubMed - indexed for MEDLINE]Related articles

    18.

    Genetic modulation of tau phosphorylation in the mouse.

    Brich J, Shie FS, Howell BW, Li R, Tus K, Wakeland EK, Jin LW, Mumby M, Churchill G, Herz J, Cooper JA.

    J Neurosci. 2003 Jan 1;23(1):187-92.PMID: 12514215 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Effect of cortistatin on tau phosphorylation at Ser262 site.

    Rubio A, Pérez M, de Lecea L, Avila J.

    J Neurosci Res. 2008 Aug 15;86(11):2462-75.PMID: 18438934 [PubMed - indexed for MEDLINE]Related articles

    20.

    Spatial and temporal distribution of intracellular free cholesterol in brains of a Niemann-Pick type C mouse model showing hyperphosphorylated tau protein. Implications for Alzheimer's disease.

    Treiber-Held S, Distl R, Meske V, Albert F, Ohm TG.

    J Pathol. 2003 May;200(1):95-103.PMID: 12692847 [PubMed - indexed for MEDLINE]Related articles

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