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    Results: 1 to 20 of 288

    1.

    Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells.

    Tweedie E, Artner I, Crawford L, Poffenberger G, Thorens B, Stein R, Powers AC, Gannon M.

    Diabetes. 2006 Dec;55(12):3264-70.PMID: 17130469 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.

    Gannon M, Ray MK, Van Zee K, Rausa F, Costa RH, Wright CV.

    Development. 2000 Jul;127(13):2883-95.PMID: 10851133 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Nkx2.2 regulates beta-cell function in the mature islet.

    Doyle MJ, Sussel L.

    Diabetes. 2007 Aug;56(8):1999-2007. Epub 2007 Apr 24.PMID: 17456846 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.

    Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV.

    Dev Biol. 2008 Feb 15;314(2):406-17. Epub 2007 Nov 4.PMID: 18155690 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursors.

    Wilding L, Gannon M.

    Diabetes Metab Res Rev. 2004 Mar-Apr;20(2):114-23. Review.PMID: 15037986 [PubMed - indexed for MEDLINE]Related articles

    6.

    Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis.

    Wilding Crawford L, Tweedie Ables E, Oh YA, Boone B, Levy S, Gannon M.

    PLoS One. 2008 Feb 20;3(2):e1611.PMID: 18297134 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells.

    Poll AV, Pierreux CE, Lokmane L, Haumaitre C, Achouri Y, Jacquemin P, Rousseau GG, Cereghini S, Lemaigre FP.

    Diabetes. 2006 Jan;55(1):61-9.PMID: 16380477 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis.

    Hara M, Shen J, Pugh W, Polonsky KS, Le Beau MM, Bell GI.

    Exp Clin Endocrinol Diabetes. 2007 Nov;115(10):654-61.PMID: 18058600 [PubMed - indexed for MEDLINE]Related articles

    9.

    Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice.

    Wagner M, Koschnick S, Beilke S, Frey M, Adler G, Schmid RM.

    Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1139-47. Epub 2008 Mar 27.PMID: 18372394 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Effect of aging on insulin secretory function and expression of beta cell function-related genes of islets.

    Ihm SH, Moon HJ, Kang JG, Park CY, Oh KW, Jeong IK, Oh YS, Park SW.

    Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S150-4. Epub 2007 Apr 30.PMID: 17467845 [PubMed - indexed for MEDLINE]Related articles

    11.

    Altered pancreatic morphology in the offspring of pregnant rats given reduced dietary protein is time and gender specific.

    Chamson-Reig A, Thyssen SM, Arany E, Hill DJ.

    J Endocrinol. 2006 Oct;191(1):83-92.PMID: 17065391 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function.

    Kaneto H, Miyatsuka T, Kawamori D, Yamamoto K, Kato K, Shiraiwa T, Katakami N, Yamasaki Y, Matsuhisa M, Matsuoka TA.

    Endocr J. 2008 May;55(2):235-52. Epub 2007 Oct 15. Review.PMID: 17938503 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.

    Yamagata K, Nammo T, Moriwaki M, Ihara A, Iizuka K, Yang Q, Satoh T, Li M, Uenaka R, Okita K, Iwahashi H, Zhu Q, Cao Y, Imagawa A, Tochino Y, Hanafusa T, Miyagawa J, Matsuzawa Y.

    Diabetes. 2002 Jan;51(1):114-23.PMID: 11756330 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    PDX-1 functions as a master factor in the pancreas.

    Kaneto H, Matsuoka TA, Miyatsuka T, Kawamori D, Katakami N, Yamasaki Y, Matsuhisa M.

    Front Biosci. 2008 May 1;13:6406-20. Review.PMID: 18508668 [PubMed - indexed for MEDLINE]Related articles

    15.

    Origin of pancreatic endocrine cells from biliary duct epithelium.

    Eberhard D, Tosh D, Slack JM.

    Cell Mol Life Sci. 2008 Nov;65(21):3467-80.PMID: 18810318 [PubMed - indexed for MEDLINE]Related articles

    16.

    Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2.

    Guillam MT, Hümmler E, Schaerer E, Yeh JI, Birnbaum MJ, Beermann F, Schmidt A, Dériaz N, Thorens B.

    Nat Genet. 1997 Nov;17(3):327-30. Erratum in: Nat Genet 1997 Dec;17(4):503. Wu JY [corrected to Yeh JI]. PMID: 9354799 [PubMed - indexed for MEDLINE]Related articles

    17.

    Role of PDX-1 and MafA as a potential therapeutic target for diabetes.

    Kaneto H, Miyatsuka T, Fujitani Y, Noguchi H, Song KH, Yoon KH, Matsuoka TA.

    Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S127-37. Epub 2007 Apr 20. Review.PMID: 17449132 [PubMed - indexed for MEDLINE]Related articles

    18.

    Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.

    Doyle MJ, Loomis ZL, Sussel L.

    Development. 2007 Feb;134(3):515-23. Epub 2007 Jan 3.PMID: 17202186 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.

    Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA.

    J Clin Invest. 2009 Jul;119(7):1888-98.PMID: 19487809 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.

    Cantley J, Choudhury AI, Asare-Anane H, Selman C, Lingard S, Heffron H, Herrera P, Persaud SJ, Withers DJ.

    Diabetologia. 2007 Jun;50(6):1248-56. Epub 2007 Mar 29.PMID: 17393136 [PubMed - indexed for MEDLINE]Related articles

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