PubMed

Regulation of CDK4.

Bockstaele L, Coulonval K, Kooken H, Paternot S, Roger PP.

Cell Div. 2006 Nov 8;1:25.PMID: 17092340 [PubMed]Related articlesFree article

Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors".

Bockstaele L, Kooken H, Libert F, Paternot S, Dumont JE, de Launoit Y, Roger PP, Coulonval K.

Mol Cell Biol. 2006 Jul;26(13):5070-85.PMID: 16782892 [PubMed - indexed for MEDLINE]Related articlesFree article

Rb inactivation in cell cycle and cancer: the puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase.

Paternot S, Bockstaele L, Bisteau X, Kooken H, Coulonval K, Roger PP.

Cell Cycle. 2010 Feb;9(4):689-99. Epub 2010 Feb 12.PMID: 20107323 [PubMed - in process]Related articles

p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.

Ray A, James MK, Larochelle S, Fisher RP, Blain SW.

Mol Cell Biol. 2009 Feb;29(4):986-99. Epub 2008 Dec 15.PMID: 19075005 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.

Rocha AS, Paternot S, Coulonval K, Dumont JE, Soares P, Roger PP.

Mol Biol Cell. 2008 Nov;19(11):4814-25. Epub 2008 Sep 17.PMID: 18799615 [PubMed - indexed for MEDLINE]Related articlesFree article

Switching cyclin D-Cdk4 kinase activity on and off.

Blain SW.

Cell Cycle. 2008 Apr 1;7(7):892-8. Epub 2008 Jan 18. Review.PMID: 18414028 [PubMed - indexed for MEDLINE]Related articles

Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation.

Paternot S, Roger PP.

Cancer Res. 2009 Jun 1;69(11):4577-81. Epub 2009 May 19.PMID: 19458076 [PubMed - indexed for MEDLINE]Related articles

Structural basis for the modulation of CDK-dependent/independent activity of cyclin D1.

Ferrer JL, Dupuy J, Borel F, Jacquamet L, Noel JP, Dulic V.

Cell Cycle. 2006 Dec;5(23):2760-8. Epub 2006 Dec 1.PMID: 17172845 [PubMed - indexed for MEDLINE]Related articles

CDK4 activity in mouse embryos expressing a single D-type cyclin.

Ciemerych MA, Yu Q, Szczepanska K, Sicinski P.

Int J Dev Biol. 2008;52(2-3):299-305.PMID: 18311721 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of the cyclin-dependent kinase inhibitors p21(Cip1) and p27(Kip1) by phosphorylation directed by the cyclin encoded by Murine Herpesvirus 68.

Yarmishyn A, Child ES, Elphick LM, Mann DJ.

Exp Cell Res. 2008 Jan 1;314(1):204-12. Epub 2007 Sep 29.PMID: 17997402 [PubMed - indexed for MEDLINE]Related articles

The structure of CDK4/cyclin D3 has implications for models of CDK activation.

Takaki T, Echalier A, Brown NR, Hunt T, Endicott JA, Noble ME.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4171-6. Epub 2009 Feb 23.PMID: 19237555 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional regulation of D-type cyclins by insulin-like growth factor-I and serum in multiple myeloma cells.

Glassford J, Rabin N, Lam EW, Yong KL.

Br J Haematol. 2007 Oct;139(2):243-54.PMID: 17897300 [PubMed - indexed for MEDLINE]Related articles

Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia.

Wang L, Wang J, Blaser BW, Duchemin AM, Kusewitt DF, Liu T, Caligiuri MA, Briesewitz R.

Blood. 2007 Sep 15;110(6):2075-83. Epub 2007 May 30.PMID: 17537993 [PubMed - indexed for MEDLINE]Related articlesFree article

CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes.

Wierød L, Rosseland CM, Lindeman B, Oksvold MP, Grøsvik H, Skarpen E, Huitfeldt HS.

Cell Prolif. 2007 Aug;40(4):475-87.PMID: 17635516 [PubMed - indexed for MEDLINE]Related articles

Functions, regulation and cellular localization of plant cyclin-dependent kinase inhibitors.

Wang H, Zhou Y, Bird DA, Fowke LC.

J Microsc. 2008 Aug;231(2):234-46. Review.PMID: 18778421 [PubMed - indexed for MEDLINE]Related articles

Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin.

Bryja V, Pacherník J, Vondrácek J, Soucek K, Cajánek L, Horvath V, Holubcová Z, Dvorák P, Hampl A.

Cell Prolif. 2008 Dec;41(6):875-93.PMID: 19040567 [PubMed - indexed for MEDLINE]Related articlesFree article

Crystal structure of human CDK4 in complex with a D-type cyclin.

Day PJ, Cleasby A, Tickle IJ, O'Reilly M, Coyle JE, Holding FP, McMenamin RL, Yon J, Chopra R, Lengauer C, Jhoti H.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4166-70. Epub 2009 Feb 23.PMID: 19237565 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.

Larrea MD, Liang J, Da Silva T, Hong F, Shao SH, Han K, Dumont D, Slingerland JM.

Mol Cell Biol. 2008 Oct;28(20):6462-72. Epub 2008 Aug 18.PMID: 18710949 [PubMed - indexed for MEDLINE]Related articlesFree article

CDK inhibitors: cell cycle regulators and beyond.

Besson A, Dowdy SF, Roberts JM.

Dev Cell. 2008 Feb;14(2):159-69. Review.PMID: 18267085 [PubMed - indexed for MEDLINE]Related articles

In vitro antitumor properties of a novel cyclin-dependent kinase inhibitor, P276-00.

Joshi KS, Rathos MJ, Joshi RD, Sivakumar M, Mascarenhas M, Kamble S, Lal B, Sharma S.

Mol Cancer Ther. 2007 Mar;6(3):918-25.PMID: 17363486 [PubMed - indexed for MEDLINE]Related articlesFree article