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Hierarchical amino acid utilization and its influence on fermentation dynamics: rifamycin B fermentation using Amycolatopsis mediterranei S699, a case study.
Bapat PM, Das D, Sohoni SV, Wangikar PP.
Microb Cell Fact. 2006 Nov 2;5:32.PMID: 17081297 [PubMed]Related articlesFree article
Structured kinetic model to represent the utilization of multiple substrates in complex media during rifamycin B fermentation.
Bapat PM, Bhartiya S, Venkatesh KV, Wangikar PP.
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A cybernetic model to predict the effect of freely available nitrogen substrate on rifamycin B production in complex media.
Bapat PM, Sohoni SV, Moses TA, Wangikar PP.
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Phase shifts in the stoichiometry of rifamycin B fermentation and correlation with the trends in the parameters measured online.
Bapat PM, Das D, Dave NN, Wangikar PP.
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Substrate uptake, phosphorus repression, and effect of seed culture on glycopeptide antibiotic production: process model development and experimental validation.
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MoeA, an enzyme in the molybdopterin synthesis pathway, is required for rifamycin SV production in Amycolatopsis mediterranei U32.
Wang W, Zhang W, Lu J, Yang Y, Chiao J, Zhao G, Jiang W.
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A hybrid model of anaerobic E. coli GJT001: combination of elementary flux modes and cybernetic variables.
Kim JI, Varner JD, Ramkrishna D.
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Isolation and characterization of 27-O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercular drug rifamycin B by Amycolatopsis mediterranei S699.
Xu J, Mahmud T, Floss HG.
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Improvement of industry-applied rifamycin B-producing strain, Amycolatopsis mediterranei, by rational screening.
Jin ZH, Lin JP, Xu ZN, Cen PL.
J Gen Appl Microbiol. 2002 Dec;48(6):329-34.PMID: 12682871 [PubMed - indexed for MEDLINE]Related articlesFree article
Detection of phase shifts in batch fermentation via statistical analysis of the online measurements: a case study with rifamycin B fermentation.
Doan XT, Srinivasan R, Bapat PM, Wangikar PP.
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Cybernetic modeling of growth in mixed, substitutable substrate environments: Preferential and simultaneous utilization.
Ramakrishna R, Ramkrishna D, Konopka AE.
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Expression of the bacterial hemoglobin gene from Vitreoscilla stercoraria increases rifamycin B production in Amycolatopsis mediterranei.
Priscila G, Fernández FJ, Absalón AE, Suarez Mdel R, Sainoz M, Barrios-González J, Mejía A.
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Addition of ammonia or amino acids to a nitrogen-depleted medium affects gene expression patterns in yeast cells during alcoholic fermentation.
Jiménez-Martí E, del Olmo ML.
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Influence of amino acids on nitrogen fixation ability and growth of Azospirillum spp.
Hartmann A, Fu HA, Burris RH.
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Biochemical mechanism of the effect of barbital on rifamycin B biosynthesis by Amycolatopsis mediterranei (M18 strain).
Mejía A, Viniegra-González G, Barrios-González J.
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Effect of uracil on rifamycin SV production by Amycolatopsis mediterranei MV35R.
Murali Krishna PS, Venkateswarlu G, Venkateswar Rao L.
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Optimization of rifamycin B fermentation in shake flasks via a machine-learning-based approach.
Bapat PM, Wangikar PP.
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Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699.
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Development of balanced medium composition for improved rifamycin B production by isolated Amycolatopsis sp. RSP-3.
Mahalaxmi Y, Sathish T, Prakasham RS.
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A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. II. Isolation and characterization of a shikimate excreting auxotrophic mutant of Nocardia mediterranei with normal rifamycin-production.
Ghisalba O, Nüesch J.
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