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The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study.

van Hove EC, Hansen T, Dekker JM, Reiling E, Nijpels G, Jørgensen T, Borch-Johnsen K, Hamid YH, Heine RJ, Pedersen O, Maassen JA, 't Hart LM.

Diabetes. 2006 Nov;55(11):3193-6.PMID: 17065362 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural organization of the human short-chain L-3-hydroxyacyl-CoA dehydrogenase gene.

Vredendaal PJ, van den Berg IE, Stroobants AK, van der A DL, Malingré HE, Berger R.

Mamm Genome. 1998 Sep;9(9):763-8.PMID: 9716664 [PubMed - indexed for MEDLINE]Related articles

Specificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin release.

Martens GA, Vervoort A, Van de Casteele M, Stangé G, Hellemans K, Van Thi HV, Schuit F, Pipeleers D.

J Biol Chem. 2007 Jul 20;282(29):21134-44. Epub 2007 May 9.PMID: 17491019 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.

Clayton PT, Eaton S, Aynsley-Green A, Edginton M, Hussain K, Krywawych S, Datta V, Malingre HE, Berger R, van den Berg IE.

J Clin Invest. 2001 Aug;108(3):457-65.PMID: 11489939 [PubMed - indexed for MEDLINE]Related articlesFree article

Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation.

Molven A, Matre GE, Duran M, Wanders RJ, Rishaug U, Njølstad PR, Jellum E, Søvik O.

Diabetes. 2004 Jan;53(1):221-7.PMID: 14693719 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with hyperinsulinism: a novel glucose-fatty acid cycle?

Eaton S, Chatziandreou I, Krywawych S, Pen S, Clayton PT, Hussain K.

Biochem Soc Trans. 2003 Dec;31(Pt 6):1137-9. Review.PMID: 14641012 [PubMed - indexed for MEDLINE]Related articles

Reye-like syndrome resulting from novel missense mutations in mitochondrial medium- and short-chain l-3-hydroxy-acyl-CoA dehydrogenase.

Bennett MJ, Russell LK, Tokunaga C, Narayan SB, Tan L, Seegmiller A, Boriack RL, Strauss AW.

Mol Genet Metab. 2006 Sep-Oct;89(1-2):74-9. Epub 2006 May 24.PMID: 16725361 [PubMed - indexed for MEDLINE]Related articles

Hyperinsulinism of infancy associated with a novel splice site mutation in the SCHAD gene.

Hussain K, Clayton PT, Krywawych S, Chatziandreou I, Mills P, Ginbey DW, Geboers AJ, Berger R, van den Berg IE, Eaton S.

J Pediatr. 2005 May;146(5):706-8.PMID: 15870679 [PubMed - indexed for MEDLINE]Related articles

3-Hydroxyacyl-CoA dehydrogenase and short chain 3-hydroxyacyl-CoA dehydrogenase in human health and disease.

Yang SY, He XY, Schulz H.

FEBS J. 2005 Oct;272(19):4874-83. Review.PMID: 16176262 [PubMed - indexed for MEDLINE]Related articlesFree article

Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis.

Das SK, Sharma NK, Chu WS, Wang H, Elbein SC.

BMC Med Genet. 2008 Mar 17;9:16.PMID: 18366646 [PubMed - indexed for MEDLINE]Related articlesFree article

AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.

Andersen G, Burgdorf KS, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetes. 2008 May;57(5):1427-32. Epub 2008 Mar 3.PMID: 18316360 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW.

Diabetes. 2008 Apr;57(4):1093-100. Epub 2008 Feb 5.PMID: 18252897 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.

't Hart LM, Hansen T, Rietveld I, Dekker JM, Nijpels G, Janssen GM, Arp PA, Uitterlinden AG, Jørgensen T, Borch-Johnsen K, Pols HA, Pedersen O, van Duijn CM, Heine RJ, Maassen JA.

Diabetes. 2005 Jun;54(6):1892-5.PMID: 15919814 [PubMed - indexed for MEDLINE]Related articlesFree article

The association of genetic variants in Krüppel-like factor 11 and Type 2 diabetes in the Japanese population.

Tanahashi T, Shinohara K, Keshavarz P, Yamaguchi Y, Miyawaki K, Kunika K, Moritani M, Nakamura N, Yoshikawa T, Shiota H, Inoue H, Itakura M.

Diabet Med. 2008 Jan;25(1):19-26.PMID: 18199129 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of short-chain hydroxyacyl CoA dehydrogenases in SCHAD deficiency.

Filling C, Keller B, Hirschberg D, Marschall HU, Jörnvall H, Bennett MJ, Oppermann U.

Biochem Biophys Res Commun. 2008 Mar 28;368(1):6-11. Epub 2007 Nov 26.PMID: 18036338 [PubMed - indexed for MEDLINE]Related articles

Zinc transporter-8 gene (SLC30A8) is associated with type 2 diabetes in Chinese.

Xiang J, Li XY, Xu M, Hong J, Huang Y, Tan JR, Lu X, Dai M, Yu B, Ning G.

J Clin Endocrinol Metab. 2008 Oct;93(10):4107-12. Epub 2008 Jul 15.PMID: 18628523 [PubMed - indexed for MEDLINE]Related articlesFree article

Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians.

Meex SJ, van Greevenbroek MM, Ayoubi TA, Vlietinck R, van Vliet-Ostaptchouk JV, Hofker MH, Vermeulen VM, Schalkwijk CG, Feskens EJ, Boer JM, Stehouwer CD, van der Kallen CJ, de Bruin TW.

J Clin Endocrinol Metab. 2007 Jul;92(7):2720-5. Epub 2007 Apr 17.PMID: 17440018 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic association of single nucleotide polymorphisms in endonuclease G-like 1 gene with type 2 diabetes in a Japanese population.

Moritani M, Nomura K, Tanahashi T, Osabe D, Fujita Y, Shinohara S, Yamaguchi Y, Keshavarz P, Kudo E, Nakamura N, Yoshikawa T, Ichiishi E, Takata Y, Yasui N, Shiota H, Kunika K, Inoue H, Itakura M.

Diabetologia. 2007 Jun;50(6):1218-27. Epub 2007 Apr 6.PMID: 17415550 [PubMed - indexed for MEDLINE]Related articles

Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects.

Gjesing AP, Andersen G, Burgdorf KS, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2007 Mar;50(3):563-8. Epub 2007 Jan 13.PMID: 17221209 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion.

Holmkvist J, Tojjar D, Almgren P, Lyssenko V, Lindgren CM, Isomaa B, Tuomi T, Berglund G, Renström E, Groop L.

Diabetologia. 2007 Dec;50(12):2467-75. Epub 2007 Oct 13.PMID: 17934712 [PubMed - indexed for MEDLINE]Related articles