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Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.
Ohshiro Y, Ma RC, Yasuda Y, Hiraoka-Yamamoto J, Clermont AC, Isshiki K, Yagi K, Arikawa E, Kern TS, King GL.
Diabetes. 2006 Nov;55(11):3112-20.PMID: 17065350 [PubMed - indexed for MEDLINE]Related articlesFree article
Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model.
Meier M, Park JK, Overheu D, Kirsch T, Lindschau C, Gueler F, Leitges M, Menne J, Haller H.
Diabetes. 2007 Feb;56(2):346-54.PMID: 17259378 [PubMed - indexed for MEDLINE]Related articlesFree article
Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice.
Menne J, Park JK, Boehne M, Elger M, Lindschau C, Kirsch T, Meier M, Gueler F, Fiebeler A, Bahlmann FH, Leitges M, Haller H.
Diabetes. 2004 Aug;53(8):2101-9.PMID: 15277392 [PubMed - indexed for MEDLINE]Related articlesFree article
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.
Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R.
FASEB J. 2000 Mar;14(3):439-47.PMID: 10698958 [PubMed - indexed for MEDLINE]Related articlesFree article
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice.
Sharma K, Jin Y, Guo J, Ziyadeh FN.
Diabetes. 1996 Apr;45(4):522-30.PMID: 8603776 [PubMed - indexed for MEDLINE]Related articles
Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha.
Lindschau C, Quass P, Menne J, Güler F, Fiebeler A, Leitges M, Luft FC, Haller H.
Hypertension. 2003 Sep;42(3):335-41. Epub 2003 Aug 25.PMID: 12939231 [PubMed - indexed for MEDLINE]Related articlesFree article
Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy.
Fujimoto M, Maezawa Y, Yokote K, Joh K, Kobayashi K, Kawamura H, Nishimura M, Roberts AB, Saito Y, Mori S.
Biochem Biophys Res Commun. 2003 Jun 13;305(4):1002-7.PMID: 12767930 [PubMed - indexed for MEDLINE]Related articles
Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress.
Menini S, Amadio L, Oddi G, Ricci C, Pesce C, Pugliese F, Giorgio M, Migliaccio E, Pelicci P, Iacobini C, Pugliese G.
Diabetes. 2006 Jun;55(6):1642-50.PMID: 16731826 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of protein kinase C activation and the vascular complications of diabetes.
Das Evcimen N, King GL.
Pharmacol Res. 2007 Jun;55(6):498-510. Epub 2007 May 5. Review.PMID: 17574431 [PubMed - indexed for MEDLINE]Related articles
Pathogenesis of diabetic nephropathy: the role of oxidative stress and protein kinase C.
Ha H, Kim KH.
Diabetes Res Clin Pract. 1999 Sep;45(2-3):147-51. Review.PMID: 10588367 [PubMed - indexed for MEDLINE]Related articles
Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes.
Way KJ, Isshiki K, Suzuma K, Yokota T, Zvagelsky D, Schoen FJ, Sandusky GE, Pechous PA, Vlahos CJ, Wakasaki H, King GL.
Diabetes. 2002 Sep;51(9):2709-18.PMID: 12196463 [PubMed - indexed for MEDLINE]Related articlesFree article
Evaluation of renal gene expression of protein kinase C (PKC) isoforms in diabetic and nondiabetic proliferative glomerular diseases.
Ibrahim S, Rashed L, Fadda S.
ScientificWorldJournal. 2008 Aug 31;8:835-44.PMID: 18758661 [PubMed - indexed for MEDLINE]Related articles
[Protein kinase C-betaI, betaII in mouse diabetic nephropathy kidney and its relation to nephroprotective actions of the angiotensin receptor blocker telmisartan]
Yao LJ, Wang JQ, Deng AG, Liu JS.
Zhonghua Yi Xue Za Zhi. 2007 Jul 24;87(28):1991-5. Chinese. PMID: 17923043 [PubMed - indexed for MEDLINE]Related articles
Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway.
Thallas-Bonke V, Lindschau C, Rizkalla B, Bach LA, Boner G, Meier M, Haller H, Cooper ME, Forbes JM.
Diabetes. 2004 Nov;53(11):2921-30.PMID: 15504973 [PubMed - indexed for MEDLINE]Related articlesFree article
Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control.
Langham RG, Kelly DJ, Gow RM, Zhang Y, Cox AJ, Qi W, Thai K, Pollock CA, Christensen PK, Parving HH, Gilbert RE.
Diabetologia. 2008 Apr;51(4):668-74. Epub 2008 Feb 16.PMID: 18278479 [PubMed - indexed for MEDLINE]Related articles
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: changes in expression of NADPH oxidase subunits and eNOS.
Ding H, Hashem M, Triggle C.
Eur J Pharmacol. 2007 Apr 30;561(1-3):121-8. Epub 2007 Jan 20.PMID: 17292348 [PubMed - indexed for MEDLINE]Related articles
Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.
Cohen MP, Chen S, Ziyadeh FN, Shea E, Hud EA, Lautenslager GT, Shearman CW.
Kidney Int. 2005 Oct;68(4):1554-61.PMID: 16164632 [PubMed - indexed for MEDLINE]Related articles
Thrombospondin-1 is an endogenous activator of TGF-beta in experimental diabetic nephropathy in vivo.
Daniel C, Schaub K, Amann K, Lawler J, Hugo C.
Diabetes. 2007 Dec;56(12):2982-9. Epub 2007 Sep 18.PMID: 17878288 [PubMed - indexed for MEDLINE]Related articlesFree article
Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.
Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H.
Diabetes. 2005 Oct;54(10):2891-903. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16186390 [PubMed - indexed for MEDLINE]Related articlesFree article
Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol.
Koya D, Lee IK, Ishii H, Kanoh H, King GL.
J Am Soc Nephrol. 1997 Mar;8(3):426-35.PMID: 9071711 [PubMed - indexed for MEDLINE]Related articlesFree article
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