PubMed

p27 Regulates the transition of beta-cells from quiescence to proliferation.

Georgia S, Bhushan A.

Diabetes. 2006 Nov;55(11):2950-6.PMID: 17065330 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells.

Zhong L, Georgia S, Tschen SI, Nakayama K, Nakayama K, Bhushan A.

J Clin Invest. 2007 Oct;117(10):2869-76.PMID: 17823659 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

Agudo J, Ayuso E, Jimenez V, Salavert A, Casellas A, Tafuro S, Haurigot V, Ruberte J, Segovia JC, Bueren J, Bosch F.

Diabetologia. 2008 Oct;51(10):1862-72. Epub 2008 Jul 29.PMID: 18663428 [PubMed - indexed for MEDLINE]Related articles

High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

Masson E, Koren S, Razik F, Goldberg H, Kwan EP, Sheu L, Gaisano HY, Fantus IG.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1251-61. Epub 2009 Feb 17.PMID: 19223654 [PubMed - indexed for MEDLINE]Related articles

Differential effects of p27 in regulation of beta-cell mass during development, neonatal period, and adult life.

Rachdi L, Balcazar N, Elghazi L, Barker DJ, Krits I, Kiyokawa H, Bernal-Mizrachi E.

Diabetes. 2006 Dec;55(12):3520-8.PMID: 17130500 [PubMed - indexed for MEDLINE]Related articlesFree article

Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.

Mwangi S, Anitha M, Mallikarjun C, Ding X, Hara M, Parsadanian A, Larsen CP, Thule P, Sitaraman SV, Anania F, Srinivasan S.

Gastroenterology. 2008 Mar;134(3):727-37. Epub 2008 Feb 1.PMID: 18241861 [PubMed - indexed for MEDLINE]Related articles

Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice.

Tschen SI, Dhawan S, Gurlo T, Bhushan A.

Diabetes. 2009 Jun;58(6):1312-20. Epub 2009 Feb 19.PMID: 19228811 [PubMed - indexed for MEDLINE]Related articlesFree article

c-Kit in early onset of diabetes: a morphological and functional analysis of pancreatic beta-cells in c-KitW-v mutant mice.

Krishnamurthy M, Ayazi F, Li J, Lyttle AW, Woods M, Wu Y, Yee SP, Wang R.

Endocrinology. 2007 Nov;148(11):5520-30. Epub 2007 Aug 2.PMID: 17673521 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats.

Irako T, Akamizu T, Hosoda H, Iwakura H, Ariyasu H, Tojo K, Tajima N, Kangawa K.

Diabetologia. 2006 Jun;49(6):1264-73. Epub 2006 Mar 29.PMID: 16570155 [PubMed - indexed for MEDLINE]Related articles

Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes.

Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J, Magnuson MA, Wu H.

Mol Cell Biol. 2006 Apr;26(7):2772-81.PMID: 16537919 [PubMed - indexed for MEDLINE]Related articlesFree article

Streptozotocin-induced diabetes can be reversed by hepatic oval cell activation through hepatic transdifferentiation and pancreatic islet regeneration.

Kim S, Shin JS, Kim HJ, Fisher RC, Lee MJ, Kim CW.

Lab Invest. 2007 Jul;87(7):702-12. Epub 2007 May 7.PMID: 17483848 [PubMed - indexed for MEDLINE]Related articlesFree article

The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.

Zhang H, Ackermann AM, Gusarova GA, Lowe D, Feng X, Kopsombut UG, Costa RH, Gannon M.

Mol Endocrinol. 2006 Aug;20(8):1853-66. Epub 2006 Mar 23.PMID: 16556734 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetes.

Jackerott M, Møldrup A, Thams P, Galsgaard ED, Knudsen J, Lee YC, Nielsen JH.

Diabetes. 2006 Oct;55(10):2705-12.PMID: 17003334 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models.

Liadis N, Salmena L, Kwan E, Tajmir P, Schroer SA, Radziszewska A, Li X, Sheu L, Eweida M, Xu S, Gaisano HY, Hakem R, Woo M.

Diabetes. 2007 Sep;56(9):2302-11. Epub 2007 Jun 11.PMID: 17563067 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance and increased pancreatic beta-cell proliferation in mice expressing a mutant insulin receptor (P1195L).

Ogino J, Sakurai K, Yoshiwara K, Suzuki Y, Ishizuka N, Seki N, Suzuki Y, Koseki H, Shirasawa T, Hashimoto N, Yagui K, Saito Y.

J Endocrinol. 2006 Sep;190(3):739-47.PMID: 17003275 [PubMed - indexed for MEDLINE]Related articlesFree article

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.

Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD.

Genome Res. 2008 May;18(5):706-16. Epub 2008 Mar 17.PMID: 18347327 [PubMed - indexed for MEDLINE]Related articlesFree article

Remission of diabetes by beta-cell regeneration in diabetic mice treated with a recombinant adenovirus expressing betacellulin.

Shin S, Li N, Kobayashi N, Yoon JW, Jun HS.

Mol Ther. 2008 May;16(5):854-61. Epub 2008 Mar 18. Erratum in: Mol Ther. 2008 Jul;16(7):1347. PMID: 18388935 [PubMed - indexed for MEDLINE]Related articles

Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

Matsumura K, Chang BH, Fujimiya M, Chen W, Kulkarni RN, Eguchi Y, Kimura H, Kojima H, Chan L.

Mol Cell Biol. 2007 Sep;27(17):6026-37. Epub 2007 Jun 18. Erratum in: Mol Cell Biol. 2007 Oct;27(20):7354. PMID: 17576812 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of beta-cell function of pancreatic islets isolated from bank voles developing glucose intolerance/diabetes: an animal model showing features of both type 1 and type 2 diabetes mellitus, and a possible role of the Ljungan virus.

Blixt M, Niklasson B, Sandler S.

Gen Comp Endocrinol. 2007 Oct-Dec;154(1-3):41-7. Epub 2007 Jul 4.PMID: 17686482 [PubMed - indexed for MEDLINE]Related articles

Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats.

Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC.

Diabetologia. 2007 Oct;50(10):2117-25. Epub 2007 Jul 20.PMID: 17641871 [PubMed - indexed for MEDLINE]Related articles