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    Results: 1 to 20 of 138

    1.

    Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.

    Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V, Scharfmann R, Staels B, Frühbeck G, Froguel P.

    Diabetes. 2006 Oct;55(10):2903-8.PMID: 17003360 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

    Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohankrishna P, Hattersley AT, Frayling TM, Yajnik CS.

    Diabetologia. 2007 Jan;50(1):63-7. Epub 2006 Nov 9.PMID: 17093941 [PubMed - indexed for MEDLINE]Related articles

    3.

    Effects of TCF7L2 polymorphisms on obesity in European populations.

    Cauchi S, Choquet H, Gutiérrez-Aguilar R, Capel F, Grau K, Proença C, Dina C, Duval A, Balkau B, Marre M, Potoczna N, Langin D, Horber F, Sørensen TI, Charpentier G, Meyre D, Froguel P.

    Obesity (Silver Spring). 2008 Feb;16(2):476-82.PMID: 18239663 [PubMed - indexed for MEDLINE]Related articles

    4.

    Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.

    Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M.

    Diabetologia. 2007 Jun;50(6):1192-200. Epub 2007 Apr 17.PMID: 17437080 [PubMed - indexed for MEDLINE]Related articles

    5.

    The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies.

    De Silva NM, Steele A, Shields B, Knight B, Parnell K, Weedon MN, Hattersley AT, Frayling TM.

    Diabet Med. 2007 Oct;24(10):1067-72. Epub 2007 Aug 24.PMID: 17725629 [PubMed - indexed for MEDLINE]Related articles

    6.

    Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

    Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

    Diabetes. 2006 Sep;55(9):2654-9.PMID: 16936218 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.

    González-Sánchez JL, Martínez-Larrad MT, Zabena C, Pérez-Barba M, Serrano-Ríos M.

    Diabetologia. 2008 Nov;51(11):1993-7. Epub 2008 Aug 19.PMID: 18712344 [PubMed - indexed for MEDLINE]Related articles

    8.

    TCF7L2 in the Go-DARTS study: evidence for a gene dose effect on both diabetes susceptibility and control of glucose levels.

    Kimber CH, Doney AS, Pearson ER, McCarthy MI, Hattersley AT, Leese GP, Morris AD, Palmer CN.

    Diabetologia. 2007 Jun;50(6):1186-91. Epub 2007 Apr 11.PMID: 17429603 [PubMed - indexed for MEDLINE]Related articles

    9.

    A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.

    Horikoshi M, Hara K, Ito C, Nagai R, Froguel P, Kadowaki T.

    Diabetologia. 2007 Apr;50(4):747-51. Epub 2007 Jan 24.PMID: 17245589 [PubMed - indexed for MEDLINE]Related articles

    10.

    Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome, and markers of beta cell function and insulin resistance in a population-based sample of Emirati subjects.

    Saadi H, Nagelkerke N, Carruthers SG, Benedict S, Abdulkhalek S, Reed R, Lukic M, Nicholls MG.

    Diabetes Res Clin Pract. 2008 Jun;80(3):392-8. Epub 2008 Feb 20.PMID: 18282631 [PubMed - indexed for MEDLINE]Related articles

    11.

    TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.

    Loos RJ, Franks PW, Francis RW, Barroso I, Gribble FM, Savage DB, Ong KK, O'Rahilly S, Wareham NJ.

    Diabetes. 2007 Jul;56(7):1943-7. Epub 2007 Apr 6.PMID: 17416797 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians.

    Bodhini D, Radha V, Dhar M, Narayani N, Mohan V.

    Metabolism. 2007 Sep;56(9):1174-8.PMID: 17697858 [PubMed - indexed for MEDLINE]Related articles

    13.

    Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.

    Rees SD, Bellary S, Britten AC, O'Hare JP, Kumar S, Barnett AH, Kelly MA.

    BMC Med Genet. 2008 Feb 21;9:8.PMID: 18291022 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the MONICA/KORA surveys.

    Marzi C, Huth C, Kolz M, Grallert H, Meisinger C, Wichmann HE, Rathmann W, Herder C, Illig T.

    Horm Metab Res. 2007 Jan;39(1):46-52.PMID: 17226113 [PubMed - indexed for MEDLINE]Related articles

    15.

    Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

    Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M.

    Diabetes. 2006 Sep;55(9):2649-53.PMID: 16936217 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.

    Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, Chuang LM.

    Diabetes. 2007 Oct;56(10):2631-7. Epub 2007 Jun 19.PMID: 17579206 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

    Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

    BMC Med Genet. 2008 Jul 3;9:59.PMID: 18598350 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.

    Dahlgren A, Zethelius B, Jensevik K, Syvänen AC, Berne C; ULSAM Cohort.

    Diabetologia. 2007 Sep;50(9):1852-7. Epub 2007 Jul 6.PMID: 17618413 [PubMed - indexed for MEDLINE]Related articles

    19.

    Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men.

    Zhang C, Qi L, Hunter DJ, Meigs JB, Manson JE, van Dam RM, Hu FB.

    Diabetes. 2006 Sep;55(9):2645-8.PMID: 16936216 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    TCF7L2 polymorphisms are associated with type 2 diabetes in Khatri Sikhs from North India: genetic variation affects lipid levels.

    Sanghera DK, Nath SK, Ortega L, Gambarelli M, Kim-Howard X, Singh JR, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Kamboh MI.

    Ann Hum Genet. 2008 Jul;72(Pt 4):499-509. Epub 2008 Apr 7.PMID: 18397358 [PubMed - indexed for MEDLINE]Related articles

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