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    Results: 1 to 20 of 268

    1.

    Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation.

    Coll T, Jové M, Rodríguez-Calvo R, Eyre E, Palomer X, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M.

    Diabetes. 2006 Oct;55(10):2779-87.PMID: 17003343 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

    Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME.

    J Biol Chem. 2007 May 25;282(21):15439-50. Epub 2007 Apr 6.PMID: 17416903 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation.

    Jové M, Planavila A, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M.

    Endocrinology. 2006 Jan;147(1):552-61. Epub 2005 Oct 13.PMID: 16223857 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells.

    Planavila A, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M.

    Biochim Biophys Acta. 2005 Sep 15;1736(2):120-7.PMID: 16139565 [PubMed - indexed for MEDLINE]Related articles

    5.

    Agonist-induced activation releases peroxisome proliferator-activated receptor beta/delta from its inhibition by palmitate-induced nuclear factor-kappaB in skeletal muscle cells.

    Jové M, Laguna JC, Vázquez-Carrera M.

    Biochim Biophys Acta. 2005 May 1;1734(1):52-61. Epub 2005 Mar 17.PMID: 15866483 [PubMed - indexed for MEDLINE]Related articles

    6.

    Palmitate-induced interleukin 6 production is mediated by protein kinase C and nuclear-factor kappaB activation and leads to glucose transporter 4 down-regulation in skeletal muscle cells.

    Jové M, Planavila A, Laguna JC, Vázquez-Carrera M.

    Endocrinology. 2005 Jul;146(7):3087-95. Epub 2005 Mar 31.PMID: 15802498 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway.

    Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB, Williams RS, Yan Z.

    J Biol Chem. 2005 May 20;280(20):19587-93. Epub 2005 Mar 14.PMID: 15767263 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro.

    Staiger H, Staiger K, Haas C, Weisser M, Machicao F, Häring HU.

    Diabetologia. 2005 Oct;48(10):2115-8. Epub 2005 Aug 17.PMID: 16132959 [PubMed - indexed for MEDLINE]Related articles

    9.

    PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.

    Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.

    FASEB J. 2005 Dec;19(14):2072-4. Epub 2005 Oct 3. Retraction in: FASEB J. 2009 Aug;23(8):2790. PMID: 16203862 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations.

    Irrcher I, Adhihetty PJ, Sheehan T, Joseph AM, Hood DA.

    Am J Physiol Cell Physiol. 2003 Jun;284(6):C1669-77.PMID: 12734114 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model.

    Palomer X, Alvarez-Guardia D, Rodríguez-Calvo R, Coll T, Laguna JC, Davidson MM, Chan TO, Feldman AM, Vázquez-Carrera M.

    Cardiovasc Res. 2009 Mar 1;81(4):703-12. Epub 2008 Nov 27.PMID: 19038972 [PubMed - indexed for MEDLINE]Related articles

    12.

    Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells.

    Cabrero A, Alegret M, Sanchez RM, Adzet T, Laguna JC, Carrera MV.

    J Biol Chem. 2002 Mar 22;277(12):10100-7. Epub 2002 Jan 15.PMID: 11792699 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells.

    Coll T, Eyre E, Rodríguez-Calvo R, Palomer X, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M.

    J Biol Chem. 2008 Apr 25;283(17):11107-16. Epub 2008 Feb 14.PMID: 18281277 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells.

    Kim HJ, Park KG, Yoo EK, Kim YH, Kim YN, Kim HS, Kim HT, Park JY, Lee KU, Jang WG, Kim JG, Kim BW, Lee IK.

    Antioxid Redox Signal. 2007 Mar;9(3):301-7.PMID: 17184171 [PubMed - indexed for MEDLINE]Related articles

    16.

    An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation.

    Miura S, Kawanaka K, Kai Y, Tamura M, Goto M, Shiuchi T, Minokoshi Y, Ezaki O.

    Endocrinology. 2007 Jul;148(7):3441-8. Epub 2007 Apr 19.PMID: 17446185 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Overexpression of peroxisome proliferator-activated receptor gamma coactivator-1alpha down-regulates GLUT4 mRNA in skeletal muscles.

    Miura S, Kai Y, Ono M, Ezaki O.

    J Biol Chem. 2003 Aug 15;278(33):31385-90. Epub 2003 May 30.PMID: 12777397 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes.

    Ajuwon KM, Spurlock ME.

    J Nutr. 2005 Aug;135(8):1841-6.PMID: 16046706 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells.

    Irrcher I, Ljubicic V, Hood DA.

    Am J Physiol Cell Physiol. 2009 Jan;296(1):C116-23. Epub 2008 Nov 12.PMID: 19005163 [PubMed - indexed for MEDLINE]Related articles

    20.

    Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway.

    Oliveira RL, Ueno M, de Souza CT, Pereira-da-Silva M, Gasparetti AL, Bezzera RM, Alberici LC, Vercesi AE, Saad MJ, Velloso LA.

    Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E686-95. Epub 2004 May 27.PMID: 15165993 [PubMed - indexed for MEDLINE]Related articlesFree article

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