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    Results: 1 to 20 of 161

    1.

    Suppressed insulin signaling and increased apoptosis in CD38-null islets.

    Johnson JD, Ford EL, Bernal-Mizrachi E, Kusser KL, Luciani DS, Han Z, Tran H, Randall TD, Lund FE, Polonsky KS.

    Diabetes. 2006 Oct;55(10):2737-46.PMID: 17003338 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.

    Kim BJ, Park KH, Yim CY, Takasawa S, Okamoto H, Im MJ, Kim UH.

    Diabetes. 2008 Apr;57(4):868-78. Epub 2008 Jan 9.PMID: 18184929 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Human anti-CD38 autoantibodies raise intracellular calcium and stimulate insulin release in human pancreatic islets.

    Antonelli A, Baj G, Marchetti P, Fallahi P, Surico N, Pupilli C, Malavasi F, Ferrannini E.

    Diabetes. 2001 May;50(5):985-91.PMID: 11334442 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    CD38 autoimmunity: recent advances and relevance to human diabetes.

    Antonelli A, Ferrannini E.

    J Endocrinol Invest. 2004 Jul-Aug;27(7):695-707. Review.PMID: 15505998 [PubMed - indexed for MEDLINE]Related articles

    5.

    NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells.

    Soares S, Thompson M, White T, Isbell A, Yamasaki M, Prakash Y, Lund FE, Galione A, Chini EN.

    Am J Physiol Cell Physiol. 2007 Jan;292(1):C227-39. Epub 2006 Jun 21.PMID: 16790499 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

    Johnson JD, Kuang S, Misler S, Polonsky KS.

    FASEB J. 2004 May;18(7):878-80. Epub 2004 Mar 19.PMID: 15033925 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion.

    Kato I, Yamamoto Y, Fujimura M, Noguchi N, Takasawa S, Okamoto H.

    J Biol Chem. 1999 Jan 22;274(4):1869-72.PMID: 9890936 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin.

    Dezaki K, Kakei M, Yada T.

    Diabetes. 2007 Sep;56(9):2319-27. Epub 2007 Jun 15.PMID: 17575083 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.

    Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN.

    J Clin Invest. 2007 Oct;117(10):2860-8.PMID: 17909627 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.

    Hennige AM, Ozcan U, Okada T, Jhala US, Schubert M, White MF, Kulkarni RN.

    Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E337-46. Epub 2005 Apr 12.PMID: 15827066 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis.

    Berggren PO, Yang SN, Murakami M, Efanov AM, Uhles S, Köhler M, Moede T, Fernström A, Appelskog IB, Aspinwall CA, Zaitsev SV, Larsson O, de Vargas LM, Fecher-Trost C, Weissgerber P, Ludwig A, Leibiger B, Juntti-Berggren L, Barker CJ, Gromada J, Freichel M, Leibiger IB, Flockerzi V.

    Cell. 2004 Oct 15;119(2):273-84.PMID: 15479643 [PubMed - indexed for MEDLINE]Related articles

    12.

    Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.

    Cantley J, Choudhury AI, Asare-Anane H, Selman C, Lingard S, Heffron H, Herrera P, Persaud SJ, Withers DJ.

    Diabetologia. 2007 Jun;50(6):1248-56. Epub 2007 Mar 29.PMID: 17393136 [PubMed - indexed for MEDLINE]Related articles

    13.

    Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.

    Dror V, Kalynyak TB, Bychkivska Y, Frey MH, Tee M, Jeffrey KD, Nguyen V, Luciani DS, Johnson JD.

    J Biol Chem. 2008 Apr 11;283(15):9909-16. Epub 2008 Jan 3.PMID: 18174159 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.

    Masgrau R, Churchill GC, Morgan AJ, Ashcroft SJ, Galione A.

    Curr Biol. 2003 Feb 4;13(3):247-51.PMID: 12573222 [PubMed - indexed for MEDLINE]Related articles

    15.

    Acute effects of insulin on beta-cells from transplantable human islets.

    Luciani DS, Johnson JD.

    Mol Cell Endocrinol. 2005 Sep 28;241(1-2):88-98.PMID: 16099589 [PubMed - indexed for MEDLINE]Related articles

    16.

    Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic beta-cell function and mass through IRS2 in diabetic rats.

    Park S, Hong SM, Lee JE, Sung SR.

    J Appl Physiol. 2007 Nov;103(5):1764-71. Epub 2007 Aug 30.PMID: 17761790 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Altered airway responsiveness in CD38-deficient mice.

    Deshpande DA, White TA, Guedes AG, Milla C, Walseth TF, Lund FE, Kannan MS.

    Am J Respir Cell Mol Biol. 2005 Feb;32(2):149-56. Epub 2004 Nov 19.PMID: 15557017 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization.

    Han MK, Kim SJ, Park YR, Shin YM, Park HJ, Park KJ, Park KH, Kim HK, Jang SI, An NH, Kim UH.

    J Biol Chem. 2002 Feb 15;277(7):5315-21. Epub 2001 Oct 25.PMID: 11679582 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

    Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

    Diabetes. 2008 May;57(5):1195-204. Epub 2008 Feb 14.PMID: 18276765 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells.

    Uchida T, Iwashita N, Ohara-Imaizumi M, Ogihara T, Nagai S, Choi JB, Tamura Y, Tada N, Kawamori R, Nakayama KI, Nagamatsu S, Watada H.

    J Biol Chem. 2007 Jan 26;282(4):2707-16. Epub 2006 Nov 29.PMID: 17135234 [PubMed - indexed for MEDLINE]Related articlesFree article

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