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    Results: 1 to 20 of 581

    1.

    STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetes.

    Jackerott M, Møldrup A, Thams P, Galsgaard ED, Knudsen J, Lee YC, Nielsen JH.

    Diabetes. 2006 Oct;55(10):2705-12.PMID: 17003334 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Regulation of pancreatic beta-cell mass and proliferation by SOCS-3.

    Lindberg K, Rønn SG, Tornehave D, Richter H, Hansen JA, Rømer J, Jackerott M, Billestrup N.

    J Mol Endocrinol. 2005 Oct;35(2):231-43.PMID: 16216905 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.

    Lee JY, Gavrilova O, Davani B, Na R, Robinson GW, Hennighausen L.

    Biochim Biophys Acta. 2007 Sep;1773(9):1455-61. Epub 2007 May 29.PMID: 17599554 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.

    Walz HA, Härndahl L, Wierup N, Zmuda-Trzebiatowska E, Svennelid F, Manganiello VC, Ploug T, Sundler F, Degerman E, Ahrén B, Holst LS.

    J Endocrinol. 2006 Jun;189(3):629-41.PMID: 16731793 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Destruction of pancreatic beta-cells by transgenic induction of prostaglandin E2 in the islets.

    Oshima H, Taketo MM, Oshima M.

    J Biol Chem. 2006 Sep 29;281(39):29330-6. Epub 2006 Jul 27.PMID: 16873378 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Ursolic acid enhances the cellular immune system and pancreatic beta-cell function in streptozotocin-induced diabetic mice fed a high-fat diet.

    Jang SM, Yee ST, Choi J, Choi MS, Do GM, Jeon SM, Yeo J, Kim MJ, Seo KI, Lee MK.

    Int Immunopharmacol. 2009 Jan;9(1):113-9. Epub 2008 Nov 20.PMID: 19013541 [PubMed - indexed for MEDLINE]Related articles

    7.

    Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.

    Welsh M, Christmansson L, Karlsson T, Sandler S, Welsh N.

    Mol Med. 1999 Mar;5(3):169-80.PMID: 10404514 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.

    Nagasumi K, Esaki R, Iwachidow K, Yasuhara Y, Ogi K, Tanaka H, Nakata M, Yano T, Shimakawa K, Taketomi S, Takeuchi K, Odaka H, Kaisho Y.

    Diabetes. 2009 May;58(5):1067-76. Erratum in: Diabetes. 2009 Jul;58(7):1721. PMID: 19401434 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

    Masson E, Koren S, Razik F, Goldberg H, Kwan EP, Sheu L, Gaisano HY, Fantus IG.

    Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1251-61. Epub 2009 Feb 17.PMID: 19223654 [PubMed - indexed for MEDLINE]Related articles

    10.

    Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.

    Fujinaka Y, Takane K, Yamashita H, Vasavada RC.

    J Biol Chem. 2007 Oct 19;282(42):30707-17. Epub 2007 Aug 29.PMID: 17728251 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes.

    Asghar Z, Yau D, Chan F, Leroith D, Chan CB, Wheeler MB.

    Diabetologia. 2006 Jan;49(1):90-9. Epub 2005 Dec 15. Erratum in: Diabetologia. 2006 Mar;49(3):614. PMID: 16362284 [PubMed - indexed for MEDLINE]Related articles

    12.

    Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.

    Kobayashi M, Ohnishi H, Okazawa H, Murata Y, Hayashi Y, Kobayashi H, Kitamura T, Matozaki T.

    Endocrinology. 2008 Nov;149(11):5662-9. Epub 2008 Jul 17.PMID: 18635660 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.

    Bao S, Jacobson DA, Wohltmann M, Bohrer A, Jin W, Philipson LH, Turk J.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E217-29. Epub 2007 Sep 25.PMID: 17895289 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.

    Gelling RW, Vuguin PM, Du XQ, Cui L, Rømer J, Pederson RA, Leiser M, Sørensen H, Holst JJ, Fledelius C, Johansen PB, Fleischer N, McIntosh CH, Nishimura E, Charron MJ.

    Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E695-707. Epub 2009 Jul 14.PMID: 19602585 [PubMed - indexed for MEDLINE]Related articles

    15.

    Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice.

    Sone H, Kagawa Y.

    Diabetologia. 2005 Jan;48(1):58-67. Epub 2004 Dec 29.PMID: 15624098 [PubMed - indexed for MEDLINE]Related articles

    16.

    Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.

    Mwangi S, Anitha M, Mallikarjun C, Ding X, Hara M, Parsadanian A, Larsen CP, Thule P, Sitaraman SV, Anania F, Srinivasan S.

    Gastroenterology. 2008 Mar;134(3):727-37. Epub 2008 Feb 1.PMID: 18241861 [PubMed - indexed for MEDLINE]Related articles

    17.

    Characterization of beta-cell function of pancreatic islets isolated from bank voles developing glucose intolerance/diabetes: an animal model showing features of both type 1 and type 2 diabetes mellitus, and a possible role of the Ljungan virus.

    Blixt M, Niklasson B, Sandler S.

    Gen Comp Endocrinol. 2007 Oct-Dec;154(1-3):41-7. Epub 2007 Jul 4.PMID: 17686482 [PubMed - indexed for MEDLINE]Related articles

    18.

    A novel model of type 2 diabetes mellitus based on obesity induced by high-fat diet in BDF1 mice.

    Karasawa H, Nagata-Goto S, Takaishi K, Kumagae Y.

    Metabolism. 2009 Mar;58(3):296-303.PMID: 19217442 [PubMed - indexed for MEDLINE]Related articles

    19.

    Kidney involvement in a nongenetic rat model of type 2 diabetes.

    Danda RS, Habiba NM, Rincon-Choles H, Bhandari BK, Barnes JL, Abboud HE, Pergola PE.

    Kidney Int. 2005 Dec;68(6):2562-71.PMID: 16316331 [PubMed - indexed for MEDLINE]Related articles

    20.

    Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

    Devedjian JC, George M, Casellas A, Pujol A, Visa J, Pelegrín M, Gros L, Bosch F.

    J Clin Invest. 2000 Mar;105(6):731-40.PMID: 10727441 [PubMed - indexed for MEDLINE]Related articlesFree article

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