PubMed

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M.

Diabetes. 2006 Sep;55(9):2649-53.PMID: 16936217 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohankrishna P, Hattersley AT, Frayling TM, Yajnik CS.

Diabetologia. 2007 Jan;50(1):63-7. Epub 2006 Nov 9.PMID: 17093941 [PubMed - indexed for MEDLINE]Related articles

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Nagai R, Froguel P, Kadowaki T.

Diabetologia. 2007 Apr;50(4):747-51. Epub 2007 Jan 24.PMID: 17245589 [PubMed - indexed for MEDLINE]Related articles

Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.

Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI.

Diabetes. 2007 Oct;56(10):2638-42. Epub 2007 Jun 29.PMID: 17601994 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

Diabetes. 2006 Sep;55(9):2654-9.PMID: 16936218 [PubMed - indexed for MEDLINE]Related articlesFree article

Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.

Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, Chuang LM.

Diabetes. 2007 Oct;56(10):2631-7. Epub 2007 Jun 19.PMID: 17579206 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.

Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI.

Diabetes. 2006 Sep;55(9):2640-4. Erratum in: Diabetes. 2006 Dec;55(12):3635. PMID: 16936215 [PubMed - indexed for MEDLINE]Related articlesFree article

Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.

Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Wass JA, Järvelin MR, Zeggini E, Franks S, McCarthy MI.

Diabetologia. 2007 Nov;50(11):2318-22. Epub 2007 Sep 6.PMID: 17805508 [PubMed - indexed for MEDLINE]Related articles

Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort.

van Vliet-Ostaptchouk JV, Shiri-Sverdlov R, Zhernakova A, Strengman E, van Haeften TW, Hofker MH, Wijmenga C.

Diabetologia. 2007 Jan;50(1):59-62. Epub 2006 Oct 10.PMID: 17031610 [PubMed - indexed for MEDLINE]Related articles

Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population.

Ren Q, Han XY, Wang F, Zhang XY, Han LC, Luo YY, Zhou XH, Ji LN.

Diabetologia. 2008 Jul;51(7):1146-52. Epub 2008 May 21.PMID: 18493736 [PubMed - indexed for MEDLINE]Related articles

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.

Rees SD, Bellary S, Britten AC, O'Hare JP, Kumar S, Barnett AH, Kelly MA.

BMC Med Genet. 2008 Feb 21;9:8.PMID: 18291022 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.

Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M.

Diabetologia. 2007 Jun;50(6):1192-200. Epub 2007 Apr 17.PMID: 17437080 [PubMed - indexed for MEDLINE]Related articles

Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.

González-Sánchez JL, Martínez-Larrad MT, Zabena C, Pérez-Barba M, Serrano-Ríos M.

Diabetologia. 2008 Nov;51(11):1993-7. Epub 2008 Aug 19.PMID: 18712344 [PubMed - indexed for MEDLINE]Related articles

Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population.

Hayashi T, Iwamoto Y, Kaku K, Hirose H, Maeda S.

Diabetologia. 2007 May;50(5):980-4. Epub 2007 Mar 6.PMID: 17340123 [PubMed - indexed for MEDLINE]Related articles

The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians.

Bodhini D, Radha V, Dhar M, Narayani N, Mohan V.

Metabolism. 2007 Sep;56(9):1174-8.PMID: 17697858 [PubMed - indexed for MEDLINE]Related articles

The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies.

De Silva NM, Steele A, Shields B, Knight B, Parnell K, Weedon MN, Hattersley AT, Frayling TM.

Diabet Med. 2007 Oct;24(10):1067-72. Epub 2007 Aug 24.PMID: 17725629 [PubMed - indexed for MEDLINE]Related articles

Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese.

Ng MC, Tam CH, Lam VK, So WY, Ma RC, Chan JC.

J Clin Endocrinol Metab. 2007 Sep;92(9):3733-7. Epub 2007 Jul 3.PMID: 17609304 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

BMC Med Genet. 2008 Jul 3;9:59.PMID: 18598350 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.

Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V, Scharfmann R, Staels B, Frühbeck G, Froguel P.

Diabetes. 2006 Oct;55(10):2903-8.PMID: 17003360 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSB mutations in predicting diabetes.

Mahurkar S, Bhaskar S, Reddy DN, Prakash S, Rao GV, Singh SP, Thomas V, Chandak GR.

BMC Med Genet. 2008 Aug 16;9:80.PMID: 18706099 [PubMed - indexed for MEDLINE]Related articlesFree article