PubMed

Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men.

Zhang C, Qi L, Hunter DJ, Meigs JB, Manson JE, van Dam RM, Hu FB.

Diabetes. 2006 Sep;55(9):2645-8.PMID: 16936216 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women.

Humphries SE, Gable D, Cooper JA, Ireland H, Stephens JW, Hurel SJ, Li KW, Palmen J, Miller MA, Cappuccio FP, Elkeles R, Godsland I, Miller GJ, Talmud PJ.

J Mol Med. 2006 Dec;84(12):1005-14.PMID: 17665514 [PubMed - indexed for MEDLINE]Related articles

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohankrishna P, Hattersley AT, Frayling TM, Yajnik CS.

Diabetologia. 2007 Jan;50(1):63-7. Epub 2006 Nov 9.PMID: 17093941 [PubMed - indexed for MEDLINE]Related articles

The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies.

De Silva NM, Steele A, Shields B, Knight B, Parnell K, Weedon MN, Hattersley AT, Frayling TM.

Diabet Med. 2007 Oct;24(10):1067-72. Epub 2007 Aug 24.PMID: 17725629 [PubMed - indexed for MEDLINE]Related articles

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.

Rees SD, Bellary S, Britten AC, O'Hare JP, Kumar S, Barnett AH, Kelly MA.

BMC Med Genet. 2008 Feb 21;9:8.PMID: 18291022 [PubMed - indexed for MEDLINE]Related articlesFree article

The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians.

Bodhini D, Radha V, Dhar M, Narayani N, Mohan V.

Metabolism. 2007 Sep;56(9):1174-8.PMID: 17697858 [PubMed - indexed for MEDLINE]Related articles

Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.

Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, Chuang LM.

Diabetes. 2007 Oct;56(10):2631-7. Epub 2007 Jun 19.PMID: 17579206 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects.

Salpea KD, Gable DR, Cooper JA, Stephens JW, Hurel SJ, Ireland HA, Feher MD, Godsland IF, Humphries SE.

Nutr Metab Cardiovasc Dis. 2009 Feb;19(2):140-5. Epub 2008 Jun 13.PMID: 18555673 [PubMed - indexed for MEDLINE]Related articles

Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study.

Yan Y, North KE, Ballantyne CM, Brancati FL, Chambless LE, Franceschini N, Heiss G, Kottgen A, Pankow JS, Selvin E, West SL, Boerwinkle E.

Diabetes. 2009 Jan;58(1):285-9. Epub 2008 Oct 17.PMID: 18931037 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.

Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI.

Diabetes. 2006 Sep;55(9):2640-4. Erratum in: Diabetes. 2006 Dec;55(12):3635. PMID: 16936215 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M.

Diabetes. 2006 Sep;55(9):2649-53.PMID: 16936217 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.

González-Sánchez JL, Martínez-Larrad MT, Zabena C, Pérez-Barba M, Serrano-Ríos M.

Diabetologia. 2008 Nov;51(11):1993-7. Epub 2008 Aug 19.PMID: 18712344 [PubMed - indexed for MEDLINE]Related articles

Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.

Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V, Scharfmann R, Staels B, Frühbeck G, Froguel P.

Diabetes. 2006 Oct;55(10):2903-8.PMID: 17003360 [PubMed - indexed for MEDLINE]Related articlesFree article

Whole-grain consumption and transcription factor-7-like 2 ( TCF7L2) rs7903146: gene-diet interaction in modulating type 2 diabetes risk.

Fisher E, Boeing H, Fritsche A, Doering F, Joost HG, Schulze MB.

Br J Nutr. 2009 Feb;101(4):478-81. Epub 2008 Jul 17.PMID: 19149908 [PubMed - indexed for MEDLINE]Related articles

Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population.

Hayashi T, Iwamoto Y, Kaku K, Hirose H, Maeda S.

Diabetologia. 2007 May;50(5):980-4. Epub 2007 Mar 6.PMID: 17340123 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 in the Go-DARTS study: evidence for a gene dose effect on both diabetes susceptibility and control of glucose levels.

Kimber CH, Doney AS, Pearson ER, McCarthy MI, Hattersley AT, Leese GP, Morris AD, Palmer CN.

Diabetologia. 2007 Jun;50(6):1186-91. Epub 2007 Apr 11.PMID: 17429603 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

Diabetes. 2006 Sep;55(9):2654-9.PMID: 16936218 [PubMed - indexed for MEDLINE]Related articlesFree article

Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population.

Ren Q, Han XY, Wang F, Zhang XY, Han LC, Luo YY, Zhou XH, Ji LN.

Diabetologia. 2008 Jul;51(7):1146-52. Epub 2008 May 21.PMID: 18493736 [PubMed - indexed for MEDLINE]Related articles

A variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased risk of gestational diabetes mellitus.

Shaat N, Lernmark A, Karlsson E, Ivarsson S, Parikh H, Berntorp K, Groop L.

Diabetologia. 2007 May;50(5):972-9. Epub 2007 Mar 7.PMID: 17342473 [PubMed - indexed for MEDLINE]Related articles

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.

Weedon MN, McCarthy MI, Hitman G, Walker M, Groves CJ, Zeggini E, Rayner NW, Shields B, Owen KR, Hattersley AT, Frayling TM.

PLoS Med. 2006 Oct;3(10):e374.PMID: 17020404 [PubMed - indexed for MEDLINE]Related articlesFree article