PubMed

Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk.

Samad F, Hester KD, Yang G, Hannun YA, Bielawski J.

Diabetes. 2006 Sep;55(9):2579-87.PMID: 16936207 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.

Shah C, Yang G, Lee I, Bielawski J, Hannun YA, Samad F.

J Biol Chem. 2008 May 16;283(20):13538-48. Epub 2008 Mar 22.PMID: 18359942 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of sphingolipid turnover and chronic generation of ceramide and sphingosine in liver during aging.

Lightle SA, Oakley JI, Nikolova-Karakashian MN.

Mech Ageing Dev. 2000 Dec 1;120(1-3):111-25.PMID: 11087909 [PubMed - indexed for MEDLINE]Related articles

Elevated expression of transforming growth factor-beta in adipose tissue from obese mice.

Samad F, Yamamoto K, Pandey M, Loskutoff DJ.

Mol Med. 1997 Jan;3(1):37-48.PMID: 9132278 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu.

Tani M, Igarashi Y, Ito M.

J Biol Chem. 2005 Nov 4;280(44):36592-600. Epub 2005 Aug 25.PMID: 16126722 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingomyelin metabolism is developmentally regulated in rat lung.

Longo CA, Tyler D, Mallampalli RK.

Am J Respir Cell Mol Biol. 1997 May;16(5):605-12.PMID: 9160843 [PubMed - indexed for MEDLINE]Related articles

Autoamplification of tumor necrosis factor-alpha: a potential mechanism for the maintenance of elevated tumor necrosis factor-alpha in male but not female obese mice.

Neels JG, Pandey M, Hotamisligil GS, Samad F.

Am J Pathol. 2006 Feb;168(2):435-44.PMID: 16436658 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet.

Baranowski M, Błachnio A, Zabielski P, Górski J.

J Physiol Pharmacol. 2007 Mar;58(1):57-72.PMID: 17440226 [PubMed - indexed for MEDLINE]Related articlesFree article

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome.

Yang G, Badeanlou L, Bielawski J, Roberts AJ, Hannun YA, Samad F.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E211-24. Epub 2009 May 12.PMID: 19435851 [PubMed - indexed for MEDLINE]Related articles

Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha.

Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA.

J Biol Chem. 2005 Jul 29;280(30):27879-87. Epub 2005 Jun 9.PMID: 15946935 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice.

Samad F, Loskutoff DJ.

Mol Med. 1996 Sep;2(5):568-82.PMID: 8898373 [PubMed - indexed for MEDLINE]Related articlesFree article

Measurement of ceramide and sphingolipid metabolism in tumors: potential modulation of chemotherapy.

Modrak DE.

Methods Mol Med. 2005;111:183-94.PMID: 15911980 [PubMed - indexed for MEDLINE]Related articles

Tissue factor gene expression in the adipose tissues of obese mice.

Samad F, Pandey M, Loskutoff DJ.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7591-6.PMID: 9636194 [PubMed - indexed for MEDLINE]Related articlesFree article

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice.

Hojjati MR, Li Z, Jiang XC.

Biochim Biophys Acta. 2005 Oct 15;1737(1):44-51. Epub 2005 Aug 24.PMID: 16216550 [PubMed - indexed for MEDLINE]Related articles

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids.

Kono M, Dreier JL, Ellis JM, Allende ML, Kalkofen DN, Sanders KM, Bielawski J, Bielawska A, Hannun YA, Proia RL.

J Biol Chem. 2006 Mar 17;281(11):7324-31. Epub 2005 Dec 27.PMID: 16380386 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of exercise duration on the key pathways of ceramide metabolism in rat skeletal muscles.

Błachnio-Zabielska A, Baranowski M, Zabielski P, Górski J.

J Cell Biochem. 2008 Oct 15;105(3):776-84.PMID: 18680146 [PubMed - indexed for MEDLINE]Related articles

Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis.

Neels JG, Badeanlou L, Hester KD, Samad F.

J Biol Chem. 2009 Jul 31;284(31):20692-8. Epub 2009 Jun 3.PMID: 19494115 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1.

Samad F, Uysal KT, Wiesbrock SM, Pandey M, Hotamisligil GS, Loskutoff DJ.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6902-7.PMID: 10359811 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of peroxisome proliferator-activated receptor-alpha ligands in the interaction between adipocytes and macrophages in obese adipose tissue.

Toyoda T, Kamei Y, Kato H, Sugita S, Takeya M, Suganami T, Ogawa Y.

Obesity (Silver Spring). 2008 Jun;16(6):1199-207. Epub 2008 Mar 20.PMID: 18356826 [PubMed - indexed for MEDLINE]Related articles

Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue.

Ito A, Suganami T, Yamauchi A, Degawa-Yamauchi M, Tanaka M, Kouyama R, Kobayashi Y, Nitta N, Yasuda K, Hirata Y, Kuziel WA, Takeya M, Kanegasaki S, Kamei Y, Ogawa Y.

J Biol Chem. 2008 Dec 19;283(51):35715-23. Epub 2008 Oct 30.PMID: 18977759 [PubMed - indexed for MEDLINE]Related articles