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    Results: 1 to 20 of 689

    1.

    Nuclear factor-kappaB regulates beta-cell death: a critical role for A20 in beta-cell protection.

    Liuwantara D, Elliot M, Smith MW, Yam AO, Walters SN, Marino E, McShea A, Grey ST.

    Diabetes. 2006 Sep;55(9):2491-501.PMID: 16936197 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN.

    Heyninck K, De Valck D, Vanden Berghe W, Van Criekinge W, Contreras R, Fiers W, Haegeman G, Beyaert R.

    J Cell Biol. 1999 Jun 28;145(7):1471-82.PMID: 10385526 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.

    Ortis F, Pirot P, Naamane N, Kreins AY, Rasschaert J, Moore F, Théâtre E, Verhaeghe C, Magnusson NE, Chariot A, Orntoft TF, Eizirik DL.

    Diabetologia. 2008 Jul;51(7):1213-25. Epub 2008 May 8.PMID: 18463842 [PubMed - indexed for MEDLINE]Related articles

    4.

    A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells.

    He KL, Ting AT.

    Mol Cell Biol. 2002 Sep;22(17):6034-45.PMID: 12167698 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-kappaB) signalling in human islets and in a mouse beta cell line.

    Sarkar SA, Kutlu B, Velmurugan K, Kizaka-Kondoh S, Lee CE, Wong R, Valentine A, Davidson HW, Hutton JC, Pugazhenthi S.

    Diabetologia. 2009 Jun;52(6):1092-101. Epub 2009 Apr 3.PMID: 19343319 [PubMed - indexed for MEDLINE]Related articles

    6.

    Nuclear factor kappaB protects pancreatic beta-cells from tumor necrosis factor-alpha-mediated apoptosis.

    Chang I, Kim S, Kim JY, Cho N, Kim YH, Kim HS, Lee MK, Kim KW, Lee MS.

    Diabetes. 2003 May;52(5):1169-75.PMID: 12716748 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets.

    Grey ST, Arvelo MB, Hasenkamp W, Bach FH, Ferran C.

    J Exp Med. 1999 Oct 18;190(8):1135-46.PMID: 10523611 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6.

    Heyninck K, Beyaert R.

    FEBS Lett. 1999 Jan 15;442(2-3):147-50.PMID: 9928991 [PubMed - indexed for MEDLINE]Related articles

    9.

    Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.

    Van Huffel S, Delaei F, Heyninck K, De Valck D, Beyaert R.

    J Biol Chem. 2001 Aug 10;276(32):30216-23. Epub 2001 Jun 4.PMID: 11390377 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling.

    Sato S, Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K, Akira S.

    J Immunol. 2003 Oct 15;171(8):4304-10.PMID: 14530355 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death.

    Thomas HE, Angstetra E, Fernandes RV, Mariana L, Irawaty W, Jamieson EL, Dudek NL, Kay TW.

    Immunol Cell Biol. 2006 Feb;84(1):20-7. Epub 2005 Nov 7.PMID: 16277639 [PubMed - indexed for MEDLINE]Related articles

    12.

    cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells.

    Cottet S, Dupraz P, Hamburger F, Dolci W, Jaquet M, Thorens B.

    Diabetes. 2002 Jun;51(6):1805-14.PMID: 12031968 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Human RPE expression of cell survival factors.

    Yang P, Wiser JL, Peairs JJ, Ebright JN, Zavodni ZJ, Bowes Rickman C, Jaffe GJ.

    Invest Ophthalmol Vis Sci. 2005 May;46(5):1755-64.PMID: 15851579 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Functional dichotomy of A20 in apoptotic and necrotic cell death.

    Storz P, Döppler H, Ferran C, Grey ST, Toker A.

    Biochem J. 2005 Apr 1;387(Pt 1):47-55.PMID: 15527421 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Oxidized LDL suppresses NF-kappaB and overcomes protection from apoptosis in activated endothelial cells.

    Heermeier K, Leicht W, Palmetshofer A, Ullrich M, Wanner C, Galle J.

    J Am Soc Nephrol. 2001 Mar;12(3):456-63.PMID: 11181793 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses.

    Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, Hurley P, Chien M, Chai S, Hitotsumatsu O, McNally E, Pickart C, Ma A.

    Nat Immunol. 2004 Oct;5(10):1052-60. Epub 2004 Aug 29. Erratum in: Nat Immunol. 2005 Jan;6(1):114. PMID: 15334086 [PubMed - indexed for MEDLINE]Related articles

    17.

    NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.

    Kreuz S, Siegmund D, Scheurich P, Wajant H.

    Mol Cell Biol. 2001 Jun;21(12):3964-73.PMID: 11359904 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Impaired TNFalpha-induced A20 expression in E1A/Ras-transformed cells.

    Huang HL, Yeh WC, Lai MZ, Mirtsos C, Chau H, Chou CH, Benchimol S.

    Br J Cancer. 2009 Nov 3;101(9):1555-64. Epub 2009 Oct 13.PMID: 19826422 [PubMed - indexed for MEDLINE]Related articles

    19.

    Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.

    Ortis F, Cardozo AK, Crispim D, Störling J, Mandrup-Poulsen T, Eizirik DL.

    Mol Endocrinol. 2006 Aug;20(8):1867-79. Epub 2006 Mar 23.PMID: 16556731 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Adenovirus-mediated expression of a dominant negative mutant of p65/RelA inhibits proinflammatory gene expression in endothelial cells without sensitizing to apoptosis.

    Soares MP, Muniappan A, Kaczmarek E, Koziak K, Wrighton CJ, Steinhäuslin F, Ferran C, Winkler H, Bach FH, Anrather J.

    J Immunol. 1998 Nov 1;161(9):4572-82.PMID: 9794384 [PubMed - indexed for MEDLINE]Related articlesFree article

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