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    Results: 1 to 20 of 643

    1.

    Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

    Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J.

    Diabetes. 2006 Sep;55(9):2470-8.PMID: 16936195 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK.

    Annerén C, Welsh M.

    Mol Med. 2001 May;7(5):301-10.PMID: 11474576 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling.

    Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G.

    Endocrinology. 2007 Feb;148(2):512-29. Epub 2006 Oct 26.PMID: 17068144 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

    Fontés G, Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V.

    Diabetes. 2009 Sep;58(9):2048-58. Epub 2009 Jun 5.PMID: 19502418 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.

    Chen YW, Huang CF, Tsai KS, Yang RS, Yen CC, Yang CY, Lin-Shiau SY, Liu SH.

    Diabetes. 2006 Jun;55(6):1614-24.PMID: 16731823 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.

    Mwangi S, Anitha M, Mallikarjun C, Ding X, Hara M, Parsadanian A, Larsen CP, Thule P, Sitaraman SV, Anania F, Srinivasan S.

    Gastroenterology. 2008 Mar;134(3):727-37. Epub 2008 Feb 1.PMID: 18241861 [PubMed - indexed for MEDLINE]Related articles

    7.

    Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

    Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

    Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.PMID: 18162507 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion.

    Bouzakri K, Ribaux P, Halban PA.

    J Biol Chem. 2009 Oct 9;284(41):27892-8. Epub 2009 Aug 18.PMID: 19690174 [PubMed - indexed for MEDLINE]Related articles

    9.

    Fibroblast growth factor receptor-1 signaling in pancreatic islet beta-cells is modulated by the extracellular matrix.

    Kilkenny DM, Rocheleau JV.

    Mol Endocrinol. 2008 Jan;22(1):196-205. Epub 2007 Oct 4.PMID: 17916654 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt.

    Yano T, Liu Z, Donovan J, Thomas MK, Habener JF.

    Diabetes. 2007 Dec;56(12):2946-57. Epub 2007 Sep 18.PMID: 17878289 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

    Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

    Diabetes. 2008 May;57(5):1195-204. Epub 2008 Feb 14.PMID: 18276765 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation.

    Fornoni A, Pileggi A, Molano RD, Sanabria NY, Tejada T, Gonzalez-Quintana J, Ichii H, Inverardi L, Ricordi C, Pastori RL.

    Diabetologia. 2008 Feb;51(2):298-308. Epub 2007 Dec 8.PMID: 18066521 [PubMed - indexed for MEDLINE]Related articles

    13.

    Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways.

    Choi SC, Kim SJ, Choi JH, Park CY, Shim WJ, Lim DS.

    Stem Cells Dev. 2008 Aug;17(4):725-36.PMID: 18788932 [PubMed - indexed for MEDLINE]Related articles

    14.

    Enhanced beta-cell mass without increased proliferation following chronic mild glucose infusion.

    Jetton TL, Everill B, Lausier J, Roskens V, Habibovic A, LaRock K, Gokin A, Peshavaria M, Leahy JL.

    Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E679-87. Epub 2008 Jan 29.PMID: 18230696 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways.

    Raucci A, Bellosta P, Grassi R, Basilico C, Mansukhani A.

    J Cell Physiol. 2008 May;215(2):442-51.PMID: 17960591 [PubMed - indexed for MEDLINE]Related articles

    16.

    Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells.

    Wang O, Cai K, Pang S, Wang T, Qi D, Zhu Q, Ni Z, Le Y.

    Endocrinology. 2008 Feb;149(2):672-80. Epub 2007 Oct 25.PMID: 17962352 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line.

    Petersen LG, Størling J, Heding P, Li S, Berezin V, Saldeen J, Billestrup N, Bock E, Mandrup-Poulsen T.

    Diabetologia. 2006 Aug;49(8):1864-75. Epub 2006 May 23.PMID: 16718462 [PubMed - indexed for MEDLINE]Related articles

    18.

    The phytostilbene resveratrol induces apoptosis in INS-1E rat insulinoma cells.

    Bortolotti C, Kunit T, Moder A, Hufnagl C, Schmidt S, Hartl A, Langelueddecke C, Fürst J, Geibel JP, Ritter M, Jakab M.

    Cell Physiol Biochem. 2009;23(4-6):245-54. Epub 2009 May 6.PMID: 19471092 [PubMed - indexed for MEDLINE]Related articles

    19.

    Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.

    Chipitsyna G, Gong Q, Gray CF, Haroon Y, Kamer E, Arafat HA.

    Endocrinology. 2007 May;148(5):2198-208. Epub 2007 Feb 15.PMID: 17303665 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice.

    Wagner M, Koschnick S, Beilke S, Frey M, Adler G, Schmid RM.

    Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1139-47. Epub 2008 Mar 27.PMID: 18372394 [PubMed - indexed for MEDLINE]Related articlesFree article

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