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The amyloid precursor protein: beyond amyloid.

Zheng H, Koo EH.

Mol Neurodegener. 2006 Jul 3;1:5.PMID: 16930452 [PubMed]Related articlesFree article

Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.

Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS.

Hum Mol Genet. 2008 Nov 15;17(22):3474-86. Epub 2008 Aug 11.PMID: 18694898 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional role of lipoprotein receptors in Alzheimer's disease.

Jaeger S, Pietrzik CU.

Curr Alzheimer Res. 2008 Feb;5(1):15-25. Review.PMID: 18288927 [PubMed - indexed for MEDLINE]Related articles

Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies.

Senechal Y, Larmet Y, Dev KK.

Neurodegener Dis. 2006;3(3):134-47. Review.PMID: 16954700 [PubMed - indexed for MEDLINE]Related articles

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease.

Dodson SE, Andersen OM, Karmali V, Fritz JJ, Cheng D, Peng J, Levey AI, Willnow TE, Lah JJ.

J Neurosci. 2008 Nov 26;28(48):12877-86.PMID: 19036982 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism.

Zhang YW, Xu H.

Curr Mol Med. 2007 Nov;7(7):687-96. Review.PMID: 18045146 [PubMed - indexed for MEDLINE]Related articles

The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins.

Anliker B, Müller U.

Neurodegener Dis. 2006;3(4-5):239-46. Review.PMID: 17047363 [PubMed - indexed for MEDLINE]Related articles

Reassessing the amyloid cascade hypothesis of Alzheimer's disease.

Pimplikar SW.

Int J Biochem Cell Biol. 2009 Jun;41(6):1261-8. Epub 2008 Dec 30. Review.PMID: 19124085 [PubMed - indexed for MEDLINE]Related articles

Induced dimerization of the amyloid precursor protein leads to decreased amyloid-beta protein production.

Eggert S, Midthune B, Cottrell B, Koo EH.

J Biol Chem. 2009 Oct 16;284(42):28943-52. Epub 2009 Jul 13.PMID: 19596858 [PubMed - indexed for MEDLINE]Related articles

Differential distribution of Alzheimer's amyloid precursor protein family variants in human sperm.

Fardilha M, Vieira SI, Barros A, Sousa M, Da Cruz e Silva OA, Da Cruz e Silva EF.

Ann N Y Acad Sci. 2007 Jan;1096:196-206.PMID: 17405931 [PubMed - indexed for MEDLINE]Related articles

The role of amyloid beta peptide 42 in Alzheimer's disease.

Findeis MA.

Pharmacol Ther. 2007 Nov;116(2):266-86. Epub 2007 Jul 17. Review.PMID: 17716740 [PubMed - indexed for MEDLINE]Related articles

TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation.

Van Vickle GD, Esh CL, Kalback WM, Patton RL, Luehrs DC, Kokjohn TA, Fifield FG, Fraser PE, Westaway D, McLaurin J, Lopez J, Brune D, Newel AJ, Poston M, Beach TG, Roher AE.

Biochemistry. 2007 Sep 11;46(36):10317-27. Epub 2007 Aug 18.PMID: 17705508 [PubMed - indexed for MEDLINE]Related articles

Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease.

Van Broeck B, Vanhoutte G, Pirici D, Van Dam D, Wils H, Cuijt I, Vennekens K, Zabielski M, Michalik A, Theuns J, De Deyn PP, Van der Linden A, Van Broeckhoven C, Kumar-Singh S.

Neurobiol Aging. 2008 Feb;29(2):241-52. Epub 2006 Nov 16.PMID: 17112635 [PubMed - indexed for MEDLINE]Related articles

Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein.

Parkin ET, Watt NT, Hussain I, Eckman EA, Eckman CB, Manson JC, Baybutt HN, Turner AJ, Hooper NM.

Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11062-7. Epub 2007 Jun 15.PMID: 17573534 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically.

Agca C, Fritz JJ, Walker LC, Levey AI, Chan AW, Lah JJ, Agca Y.

BMC Neurosci. 2008 Feb 26;9:28.PMID: 18302776 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo.

Kim ML, Zhang B, Mills IP, Milla ME, Brunden KR, Lee VM.

J Neurosci. 2008 Nov 12;28(46):12052-61.PMID: 19005070 [PubMed - indexed for MEDLINE]Related articlesFree article

Amyloid precursor protein trafficking, processing, and function.

Thinakaran G, Koo EH.

J Biol Chem. 2008 Oct 31;283(44):29615-9. Epub 2008 Jul 23. Review.PMID: 18650430 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila.

Gross GG, Feldman RM, Ganguly A, Wang J, Yu H, Guo M.

PLoS One. 2008 Jun 25;3(6):e2495.PMID: 18575606 [PubMed - indexed for MEDLINE]Related articlesFree article

The many faces of amyloid beta in Alzheimer's disease.

Chiang PK, Lam MA, Luo Y.

Curr Mol Med. 2008 Sep;8(6):580-4. Review.PMID: 18781964 [PubMed - indexed for MEDLINE]Related articles

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.

Dutescu RM, Li QX, Crowston J, Masters CL, Baird PN, Culvenor JG.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1213-21. Epub 2009 Mar 7.PMID: 19271231 [PubMed - indexed for MEDLINE]Related articles