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    Results: 1 to 20 of 290

    1.

    ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

    Vantaggiato C, Formentini I, Bondanza A, Bonini C, Naldini L, Brambilla R.

    J Biol. 2006;5(5):14.PMID: 16805921 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Novel membrane-targeted ERK1 and ERK2 chimeras which act as dominant negative, isotype-specific mitogen-activated protein kinase inhibitors of Ras-Raf-mediated transcriptional activation of c-fos in NIH 3T3 cells.

    Hochholdinger F, Baier G, Nogalo A, Bauer B, Grunicke HH, Uberall F.

    Mol Cell Biol. 1999 Dec;19(12):8052-65.PMID: 10567531 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling.

    Hong SK, Yoon S, Moelling C, Arthan D, Park JI.

    J Biol Chem. 2009 Nov 27;284(48):33006-18. Epub 2009 Oct 5.PMID: 19805545 [PubMed - indexed for MEDLINE]Related articles

    4.

    Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.

    Frémin C, Bessard A, Ezan F, Gailhouste L, Régeard M, Le Seyec J, Gilot D, Pagès G, Pouysségur J, Langouët S, Baffet G.

    Hepatology. 2009 Mar;49(3):930-9.PMID: 19177593 [PubMed - indexed for MEDLINE]Related articles

    5.

    Total ERK1/2 activity regulates cell proliferation.

    Lefloch R, Pouysségur J, Lenormand P.

    Cell Cycle. 2009 Mar 1;8(5):705-11. Epub 2009 Mar 29.PMID: 19242111 [PubMed - indexed for MEDLINE]Related articles

    6.

    ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzeta-controlled ERK1/2 activity within the nucleus.

    Godeny MD, Sayeski PP.

    Am J Physiol Cell Physiol. 2006 Dec;291(6):C1297-307. Epub 2006 May 24.PMID: 16723512 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes.

    Frémin C, Ezan F, Boisselier P, Bessard A, Pagès G, Pouysségur J, Baffet G.

    Hepatology. 2007 Apr;45(4):1035-45.PMID: 17393467 [PubMed - indexed for MEDLINE]Related articles

    8.

    RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.

    Gailhouste L, Ezan F, Bessard A, Frémin C, Rageul J, Langouët S, Baffet G.

    Int J Cancer. 2010 Mar 15;126(6):1367-77.PMID: 19816936 [PubMed - indexed for MEDLINE]Related articles

    9.

    The third cytoplasmic loop of the angiotensin II type 1 receptor exerts differential effects on extracellular signal-regulated kinase (ERK1/ERK2) and apoptosis via Ras- and Rap1-dependent pathways.

    Haendeler J, Ishida M, Hunyady L, Berk BC.

    Circ Res. 2000 Apr 14;86(7):729-36.PMID: 10764405 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels.

    Lefloch R, Pouysségur J, Lenormand P.

    Mol Cell Biol. 2008 Jan;28(1):511-27. Epub 2007 Oct 29.PMID: 17967895 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation.

    Lahlou H, Saint-Laurent N, Estève JP, Eychène A, Pradayrol L, Pyronnet S, Susini C.

    J Biol Chem. 2003 Oct 10;278(41):39356-71. Epub 2003 Jul 22.PMID: 12878607 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    PEA-15 is inhibited by adenovirus E1A and plays a role in ERK nuclear export and Ras-induced senescence.

    Gaumont-Leclerc MF, Mukhopadhyay UK, Goumard S, Ferbeyre G.

    J Biol Chem. 2004 Nov 5;279(45):46802-9. Epub 2004 Aug 25.PMID: 15331596 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.

    Lee MH, Klein RL, El-Shewy HM, Luttrell DK, Luttrell LM.

    Biochemistry. 2008 Nov 4;47(44):11682-92. Epub 2008 Oct 9.PMID: 18842004 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

    Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA.

    Oncogene. 2007 Feb 8;26(6):813-21. Epub 2006 Aug 7.PMID: 16909118 [PubMed - indexed for MEDLINE]Related articles

    15.

    The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition.

    Meloche S, Pouysségur J.

    Oncogene. 2007 May 14;26(22):3227-39. Review.PMID: 17496918 [PubMed - indexed for MEDLINE]Related articles

    16.

    Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin.

    Mitsushima M, Suwa A, Amachi T, Ueda K, Kioka N.

    J Biol Chem. 2004 Aug 13;279(33):34570-7. Epub 2004 Jun 7.PMID: 15184391 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells.

    Calipel A, Mouriaux F, Glotin AL, Malecaze F, Faussat AM, Mascarelli F.

    J Biol Chem. 2006 Apr 7;281(14):9238-50. Epub 2006 Feb 1.PMID: 16452469 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence.

    Callejas-Valera JL, Guinea-Viniegra J, Ramírez-Castillejo C, Recio JA, Galan-Moya E, Martinez N, Rojas JM, Ramón y Cajal S, Sánchez-Prieto R.

    J Biol Chem. 2008 May 9;283(19):13450-8. Epub 2008 Mar 3.PMID: 18316372 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells.

    Li BS, Veeranna, Gu J, Grant P, Pant HC.

    Eur J Biochem. 1999 May;262(1):211-7.PMID: 10231383 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer.

    Nakayama N, Nakayama K, Yeasmin S, Ishibashi M, Katagiri A, Iida K, Fukumoto M, Miyazaki K.

    Br J Cancer. 2008 Dec 16;99(12):2020-8. Epub 2008 Nov 18.PMID: 19018267 [PubMed - indexed for MEDLINE]Related articlesFree article

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