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    Results: 1 to 20 of 110

    1.

    Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.

    Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD.

    Diabetes. 2006 Jul;55(7):2153-6.PMID: 16804088 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

    Toye AA, Lippiat JD, Proks P, Shimomura K, Bentley L, Hugill A, Mijat V, Goldsworthy M, Moir L, Haynes A, Quarterman J, Freeman HC, Ashcroft FM, Cox RD.

    Diabetologia. 2005 Apr;48(4):675-86. Epub 2005 Feb 24.PMID: 15729571 [PubMed - indexed for MEDLINE]Related articles

    3.

    Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

    Freeman H, Shimomura K, Cox RD, Ashcroft FM.

    Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10.PMID: 17052203 [PubMed - indexed for MEDLINE]Related articles

    4.

    Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.

    Freeman H, Shimomura K, Horner E, Cox RD, Ashcroft FM.

    Cell Metab. 2006 Jan;3(1):35-45.PMID: 16399503 [PubMed - indexed for MEDLINE]Related articles

    5.

    Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

    Aston-Mourney K, Wong N, Kebede M, Zraika S, Balmer L, McMahon JM, Fam BC, Favaloro J, Proietto J, Morahan G, Andrikopoulos S.

    Diabetologia. 2007 Dec;50(12):2476-85. Epub 2007 Oct 6.PMID: 17922105 [PubMed - indexed for MEDLINE]Related articles

    6.

    Mitochondrial transhydrogenase--a key enzyme in insulin secretion and, potentially, diabetes.

    Rydström J.

    Trends Biochem Sci. 2006 Jul;31(7):355-8.PMID: 16766189 [PubMed - indexed for MEDLINE]Related articles

    7.

    Insulin secretion from beta-cells is affected by deletion of nicotinamide nucleotide transhydrogenase.

    Shimomura K, Galvanovskis J, Goldsworthy M, Hugill A, Kaizak S, Lee A, Meadows N, Quwailid MM, Rydström J, Teboul L, Ashcroft F, Cox RD.

    Methods Enzymol. 2009;457:451-80.PMID: 19426883 [PubMed - indexed for MEDLINE]Related articles

    8.

    Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase.

    Huang TT, Naeemuddin M, Elchuri S, Yamaguchi M, Kozy HM, Carlson EJ, Epstein CJ.

    Hum Mol Genet. 2006 Apr 1;15(7):1187-94. Epub 2006 Feb 23.PMID: 16497723 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    The Deletion Variant of Nicotinamide Nucleotide Transhydrogenase (Nnt) Does Not Affect Insulin Secretion or Glucose Tolerance.

    Wong N, Blair AR, Morahan G, Andrikopoulos S.

    Endocrinology. 2009 Nov 11. [Epub ahead of print]PMID: 19906813 [PubMed - as supplied by publisher]Related articles

    10.

    Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

    Parker N, Vidal-Puig AJ, Azzu V, Brand MD.

    Biochim Biophys Acta. 2009 Dec;1787(12):1451-7. Epub 2009 Jun 17.PMID: 19539600 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance.

    Fex M, Wierup N, Nitert MD, Ristow M, Mulder H.

    J Endocrinol. 2007 Sep;194(3):551-5. Erratum in: J Endocrinol. 2007 Dec;195(3):537. PMID: 17761894 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    A quantitative trait locus that accounts for glucose intolerance maps to chromosome 8 in hereditary obese KK-A(y) mice.

    Suto J, Sekikawa K.

    Int J Obes Relat Metab Disord. 2002 Nov;26(11):1517-9.PMID: 12439655 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Identification of two chromosomal loci determining glucose intolerance in a C57BL/6 mouse strain.

    Kayo T, Fujita H, Nozaki J, E X, Koizumi A.

    Comp Med. 2000 Jun;50(3):296-302.PMID: 10894496 [PubMed - indexed for MEDLINE]Related articles

    14.

    Differences of pancreatic expression of 7B2 between C57BL/6J and C3H/HeJ mice and genetic polymorphisms at its locus (Sgne1).

    Schmidt G, Sirois F, Anini Y, Kauri LM, Gyamera-Acheampong C, Fleck E, Scott FW, Chrétien M, Mbikay M.

    Diabetes. 2006 Feb;55(2):452-9.PMID: 16443780 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Genetic differences among C57BL/6 substrains.

    Mekada K, Abe K, Murakami A, Nakamura S, Nakata H, Moriwaki K, Obata Y, Yoshiki A.

    Exp Anim. 2009 Apr;58(2):141-9.PMID: 19448337 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress.

    Arkblad EL, Tuck S, Pestov NB, Dmitriev RI, Kostina MB, Stenvall J, Tranberg M, Rydström J.

    Free Radic Biol Med. 2005 Jun 1;38(11):1518-25.PMID: 15890626 [PubMed - indexed for MEDLINE]Related articles

    18.

    The mitochondria and insulin release: Nnt just a passing relationship.

    Remedi MS, Nichols CG, Koster JC.

    Cell Metab. 2006 Jan;3(1):5-7.PMID: 16399499 [PubMed - indexed for MEDLINE]Related articles

    19.

    Mitochondrial NADPH, transhydrogenase and disease.

    Rydström J.

    Biochim Biophys Acta. 2006 May-Jun;1757(5-6):721-6. Epub 2006 Apr 5.PMID: 16730324 [PubMed - indexed for MEDLINE]Related articles

    20.

    Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.

    Fex M, Nitert MD, Wierup N, Sundler F, Ling C, Mulder H.

    Diabetologia. 2007 Jan;50(1):74-83. Epub 2006 Nov 9.PMID: 17093947 [PubMed - indexed for MEDLINE]Related articles

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