PubMed

Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Andrulionyte L, Peltola P, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2006 Jul;55(7):2148-52.PMID: 16804087 [PubMed - indexed for MEDLINE]Related articlesFree article

Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial.

Andrulionytè L, Zacharova J, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetologia. 2004 Dec;47(12):2176-84. Epub 2004 Dec 8.PMID: 15592662 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Andrulionyte L, Kuulasmaa T, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2007 Apr;56(4):1181-6. Epub 2007 Feb 22.PMID: 17317762 [PubMed - indexed for MEDLINE]Related articlesFree article

The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects.

Fanelli M, Filippi E, Sentinelli F, Romeo S, Fallarino M, Buzzetti R, Leonetti F, Baroni MG.

Dis Markers. 2005;21(4):175-80.PMID: 16403952 [PubMed - indexed for MEDLINE]Related articles

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha gene (PGC-1alpha) is not associated with type 2 diabetes mellitus or body mass index among Hispanic and non Hispanic Whites from Colorado.

Nelson TL, Fingerlin TE, Moss L, Barmada MM, Ferrell RE, Norris JM.

Exp Clin Endocrinol Diabetes. 2007 Apr;115(4):268-75.PMID: 17479445 [PubMed - indexed for MEDLINE]Related articles

Association between peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene polymorphisms and type 2 diabetes in southern Chinese population: role of altered interaction with myocyte enhancer factor 2C.

Zhang SL, Lu WS, Yan L, Wu MC, Xu MT, Chen LH, Cheng H.

Chin Med J (Engl). 2007 Nov 5;120(21):1878-85.PMID: 18067759 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.

Stefan N, Thamer C, Staiger H, Machicao F, Machann J, Schick F, Venter C, Niess A, Laakso M, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2007 May;92(5):1827-33. Epub 2007 Feb 27.PMID: 17327385 [PubMed - indexed for MEDLINE]Related articlesFree article

The common polymorphisms (single nucleotide polymorphism [SNP] +45 and SNP +276) of the adiponectin gene predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Zacharova J, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2005 Mar;54(3):893-9.PMID: 15734870 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians.

Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Deepa R, Babu HN, Rao MR, Mohan V.

Diabet Med. 2005 Nov;22(11):1516-21.PMID: 16241916 [PubMed - indexed for MEDLINE]Related articles

Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus.

Ek J, Andersen G, Urhammer SA, Gaede PH, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O.

Diabetologia. 2001 Dec;44(12):2220-6.PMID: 11793024 [PubMed - indexed for MEDLINE]Related articles

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.

Lindi VI, Uusitupa MI, Lindström J, Louheranta A, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Tuomilehto J; Finnish Diabetes Prevention Study.

Diabetes. 2002 Aug;51(8):2581-6.PMID: 12145174 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial.

Andrulionyte L, Laukkanen O, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

J Mol Med. 2006 Aug;84(8):701-8. Epub 2006 Jul 13.PMID: 16838170 [PubMed - indexed for MEDLINE]Related articles

Effect of peroxisome proliferator-activated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people.

Hui Y, Yu-Yuan L, Yu-Qiang N, Wei-Hong S, Yan-Lei D, Xiao-Bo L, Yong-Jian Z.

Liver Int. 2008 Mar;28(3):385-92. Epub 2007 Nov 12. Erratum in: Liver Int. 2008 Feb;28(2):288. PMID: 17999673 [PubMed - indexed for MEDLINE]Related articles

[Study on the relationship between polymorphisms of peroxisome proliferators-activated receptor-gamma coactivator-1alpha gene and type 2 diabetes in Shanghai Hans in China]

Wang YB, Yu YC, Li Z, Wang C, Wang JY, Wu GT.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Aug;22(4):453-6. Chinese. PMID: 16086291 [PubMed - indexed for MEDLINE]Related articles

Genetic study between SIRT1, PPARD, PGC-1alpha genes and Alzheimer's disease.

Helisalmi S, Vepsäläinen S, Hiltunen M, Koivisto AM, Salminen A, Laakso M, Soininen H.

J Neurol. 2008 May;255(5):668-73. Epub 2008 Apr 30.PMID: 18438697 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor (PPAR) delta genetic polymorphism and its association with insulin resistance index and fasting plasma glucose concentrations in Chinese subjects.

Hu C, Jia W, Fang Q, Zhang R, Wang C, Lu J, Xiang K.

Diabet Med. 2006 Dec;23(12):1307-12.PMID: 17116180 [PubMed - indexed for MEDLINE]Related articles

Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene might be a risk factor for diabetic retinopathy in Slovene population (Caucasians) with type 2 diabetes and the Pro12Ala polymorphism of the PPARgamma gene is not.

Petrovic MG, Kunej T, Peterlin B, Dovc P, Petrovic D.

Diabetes Metab Res Rev. 2005 Sep-Oct;21(5):470-4.PMID: 15782399 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study.

Laukkanen O, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study.

Diabetes. 2005 Jul;54(7):2256-60.PMID: 15983230 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study.

Kubaszek A, Pihlajamäki J, Komarovski V, Lindi V, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study.

Diabetes. 2003 Jul;52(7):1872-6.PMID: 12829659 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans.

Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM.

Diabetes. 2008 Apr;57(4):1048-56. Epub 2007 Dec 27.PMID: 18162503 [PubMed - indexed for MEDLINE]Related articlesFree article