PubMed

Dogma disputed: can aggressively lowering blood pressure in hypertensive patients with coronary artery disease be dangerous?

Messerli FH, Mancia G, Conti CR, Hewkin AC, Kupfer S, Champion A, Kolloch R, Benetos A, Pepine CJ.

Ann Intern Med. 2006 Jun 20;144(12):884-93.PMID: 16785477 [PubMed - indexed for MEDLINE]Related articlesFree article

A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial.

Pepine CJ, Handberg EM, Cooper-DeHoff RM, Marks RG, Kowey P, Messerli FH, Mancia G, Cangiano JL, Garcia-Barreto D, Keltai M, Erdine S, Bristol HA, Kolb HR, Bakris GL, Cohen JD, Parmley WW; INVEST Investigators.

JAMA. 2003 Dec 3;290(21):2805-16.PMID: 14657064 [PubMed - indexed for MEDLINE]Related articlesFree article

Predictors of adverse outcome among patients with hypertension and coronary artery disease.

Pepine CJ, Kowey PR, Kupfer S, Kolloch RE, Benetos A, Mancia G, Coca A, Cooper-DeHoff RM, Handberg E, Gaxiola E, Sleight P, Conti CR, Hewkin AC, Tavazzi L; INVEST Investigators.

J Am Coll Cardiol. 2006 Feb 7;47(3):547-51. Epub 2006 Jan 18.PMID: 16458134 [PubMed - indexed for MEDLINE]Related articles

Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis.

Bangalore S, Messerli FH, Franklin SS, Mancia G, Champion A, Pepine CJ.

Eur Heart J. 2009 Jun;30(11):1395-401. Epub 2009 Apr 7.PMID: 19351690 [PubMed - indexed for MEDLINE]Related articles

Verapamil-sustained release-based treatment strategy is equivalent to atenolol-based treatment strategy at reducing cardiovascular events in patients with prior myocardial infarction: an INternational VErapamil SR-Trandolapril (INVEST) substudy.

Bangalore S, Messerli FH, Cohen JD, Bacher PH, Sleight P, Mancia G, Kowey P, Zhou Q, Champion A, Pepine CJ; INVEST Investigators.

Am Heart J. 2008 Aug;156(2):241-7.PMID: 18657652 [PubMed - indexed for MEDLINE]Related articles

Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension.

Pepine CJ, Handberg-Thurmond E, Marks RG, Conlon M, Cooper-DeHoff R, Volkers P, Zellig P.

J Am Coll Cardiol. 1998 Nov;32(5):1228-37.PMID: 9809930 [PubMed - indexed for MEDLINE]Related articles

Blood pressure control and cardiovascular outcomes in high-risk Hispanic patients--findings from the International Verapamil SR/Trandolapril Study (INVEST).

Cooper-DeHoff RM, Aranda JM Jr, Gaxiola E, Cangiano JL, Garcia-Barreto D, Conti CR, Hewkin A, Pepine CJ; INVEST Investigators.

Am Heart J. 2006 May;151(5):1072-9.PMID: 16644338 [PubMed - indexed for MEDLINE]Related articles

Global differences in blood pressure control and clinical outcomes in the INternational VErapamil SR-Trandolapril STudy (INVEST).

Zineh I, Cooper-Dehoff RM, Wessel TR, Arant CB, Sleight P, Geiser EA, Pepine CJ.

Clin Cardiol. 2005 Jul;28(7):321-8.PMID: 16075824 [PubMed - indexed for MEDLINE]Related articles

Predicting stroke risk in hypertensive patients with coronary artery disease: a report from the INVEST.

Coca A, Messerli FH, Benetos A, Zhou Q, Champion A, Cooper-DeHoff RM, Pepine CJ.

Stroke. 2008 Feb;39(2):343-8. Epub 2007 Dec 27.PMID: 18162623 [PubMed - indexed for MEDLINE]Related articlesFree article

Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial.

Black HR, Elliott WJ, Grandits G, Grambsch P, Lucente T, White WB, Neaton JD, Grimm RH Jr, Hansson L, Lacourciere Y, Muller J, Sleight P, Weber MA, Williams G, Wittes J, Zanchetti A, Anders RJ; CONVINCE Research Group.

JAMA. 2003 Apr 23-30;289(16):2073-82.PMID: 12709465 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity paradox in patients with hypertension and coronary artery disease.

Uretsky S, Messerli FH, Bangalore S, Champion A, Cooper-Dehoff RM, Zhou Q, Pepine CJ.

Am J Med. 2007 Oct;120(10):863-70.PMID: 17904457 [PubMed - indexed for MEDLINE]Related articles

A Study of Antihypertensive Drugs and Depressive Symptoms (SADD-Sx) in patients treated with a calcium antagonist versus an atenolol hypertension Treatment Strategy in the International Verapamil SR-Trandolapril Study (INVEST).

Ried LD, Tueth MJ, Handberg E, Kupfer S, Pepine CJ; INVEST Study Group.

Psychosom Med. 2005 May-Jun;67(3):398-406.PMID: 15911902 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.

[No authors listed]

JAMA. 1991 Jun 26;265(24):3255-64.PMID: 2046107 [PubMed - indexed for MEDLINE]Related articles

Stroke and coronary heart disease in treated hypertension -- a prospective cohort study over three decades.

Almgren T, Persson B, Wilhelmsen L, Rosengren A, Andersson OK.

J Intern Med. 2005 Jun;257(6):496-502.PMID: 15910553 [PubMed - indexed for MEDLINE]Related articles

Characteristics and outcomes of revascularized patients with hypertension: an international verapamil SR-trandolapril substudy.

Denardo SJ, Messerli FH, Gaxiola E, Aranda JM Jr, Cooper-Dehoff RM, Handberg EM, Gong Y, Champion A, Zhou Q, Pepine CJ.

Hypertension. 2009 Apr;53(4):624-30. Epub 2009 Feb 23.PMID: 19237684 [PubMed - indexed for MEDLINE]Related articles

Clinical outcomes in the diabetes cohort of the INternational VErapamil SR-Trandolapril study.

Bakris GL, Gaxiola E, Messerli FH, Mancia G, Erdine S, Cooper-DeHoff R, Pepine CJ; INVEST Investigators.

Hypertension. 2004 Nov;44(5):637-42. Epub 2004 Sep 20.PMID: 15381674 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.

Kjeldsen SE, Dahlöf B, Devereux RB, Julius S, Aurup P, Edelman J, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristianson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Snapinn S, Wedel H; LIFE (Losartan Intervention for Endpoint Reduction) Study Group.

JAMA. 2002 Sep 25;288(12):1491-8.PMID: 12243636 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood pressure reduction and antihypertensive medication use in the losartan intervention for endpoint reduction in hypertension (LIFE) study in patients with hypertension and left ventricular hypertrophy.

Devereux RB, de Faire U, Fyhrquist F, Harris KE, Ibsen H, Kjeldsen SE, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Wedel H, Hille DA, Dahlöf B.

Curr Med Res Opin. 2007 Feb;23(2):259-70.PMID: 17288679 [PubMed - indexed for MEDLINE]Related articles

Influence of Hispanic ethnicity on blood pressure control and cardiovascular outcomes in women with CAD and hypertension: findings from INVEST.

Cooper-DeHoff RM, Zhou Q, Gaxiola E, Cangiano JL, Garcia-Barreto D, Handberg E, Pepine CJ; INVEST Investigators.

J Womens Health (Larchmt). 2007 Jun;16(5):632-40.PMID: 17627399 [PubMed - indexed for MEDLINE]Related articles

Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).

Cooper-Dehoff R, Cohen JD, Bakris GL, Messerli FH, Erdine S, Hewkin AC, Kupfer S, Pepine CJ; INVEST Investigators.

Am J Cardiol. 2006 Oct 1;98(7):890-4. Epub 2006 Aug 7.PMID: 16996868 [PubMed - indexed for MEDLINE]Related articles