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Relaxin and beta-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss.
Hashem G, Zhang Q, Hayami T, Chen J, Wang W, Kapila S.
Arthritis Res Ther. 2006;8(4):R98.
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Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants.
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Arthritis Res Ther. 2005;7(1):R1-11. Epub 2004 Oct 29.
Matrix metalloproteinase induction by relaxin causes cartilage matrix degradation in target synovial joints.
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Targeted induction of collagenase and stromelysin by relaxin in unprimed and beta-estradiol-primed diarthrodial joint fibrocartilaginous cells but not in synoviocytes.
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Female hormone receptors are differentially expressed in mouse fibrocartilages.
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The effect of relaxin on collagen metabolism in the nonpregnant rat pubic symphysis: the influence of estrogen and progesterone in regulating relaxin activity.
Samuel CS, Butkus A, Coghlan JP, Bateman JF.
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Effects of relaxin, pregnancy and parturition on collagen metabolism in the rat pubic symphysis.
Samuel CS, Coghlan JP, Bateman JF.
J Endocrinol. 1998 Oct;159(1):117-25.
Induction of MMP-1 (collagenase-1) by relaxin in fibrocartilaginous cells requires both the AP-1 and PEA-3 promoter sites.
Kapila S, Xie Y, Wang W.
Orthod Craniofac Res. 2009 Aug;12(3):178-86.
Influence of ovarian steroids on relaxin-induced uterine growth in ovariectomized gilts.
Hall JA, Cantley TC, Galvin JM, Day BN, Anthony RV.
Endocrinology. 1992 Jun;130(6):3159-66.
Relaxin and collagen metabolism.
Weiss M, Nagelschmidt M, Struck H.
Horm Metab Res. 1979 Jun;11(6):408-10.
Effect of hormones on collagen metabolism and collagenase activity in the pubic symphysis ligament of the guinea pig.
Wahl LM, Blandau RJ, Page RC.
Endocrinology. 1977 Feb;100(2):571-9.
Glycosaminoglycan concentration in synovium and other tissues of rabbit knee in relation to synovial hydraulic resistance.
Price FM, Levick JR, Mason RM.
J Physiol. 1996 Sep 15;495 ( Pt 3):803-20.
The effect of TGF-beta1 and beta-estradiol on glycosaminoglycan and type II collagen distribution in articular chondrocyte cultures.
Ab-Rahim S, Selvaratnam L, Kamarul T.
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Hyaline cartilage cells outperform mandibular condylar cartilage cells in a TMJ fibrocartilage tissue engineering application.
Wang L, Lazebnik M, Detamore MS.
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The source of relaxin in pregnant Syrian hamsters.
Steinetz BG, O'Byrne EM, Goldsmith LT, Anderson MB.
Endocrinology. 1988 Mar;122(3):795-8.
Inhibition of relaxin-induced pubic symphyseal "relaxation" in guinea pigs by glycosaminoglycan polysulfates and pentosan polysulfate.
Steinetz BG, Lust G.
Agents Actions. 1994 Aug;42(1-2):74-80.
The effect of steroids and relaxin on acid phosphatase in the pubic symphysis of the ovariectomized mouse.
Manning JP, Steinetz BG, Butler MC, Priester S.
J Endocrinol. 1965 Nov;33(3):501-6. No abstract available.
Relaxin-dependent adenosine 6',5'-monophosphate concentration changes in the mouse pubic symphysis.
Braddon SA.
Endocrinology. 1978 Apr;102(4):1292-9.
[Studies on matrix components relevant to structure and function of the temporomandibular joint].
Kobayashi J.
Kokubyo Gakkai Zasshi. 1992 Mar;59(1):105-23. Japanese.
Differential distribution of the fibres of the collagenous and elastic systems and of glycosaminoglycans in the rat pubic joint.
Ortega HH, Joazeiro PP, Muñoz-de-Toro MM, Luque EH, Montes GS.
J Submicrosc Cytol Pathol. 2001 Oct;33(4):463-72.
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