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    Results: 1 to 20 of 162

    1.

    Scar wars: is TGFbeta the phantom menace in scleroderma?

    Leask A.

    Arthritis Res Ther. 2006;8(4):213. Review.

    PMID:
    16774692
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma.

    Leask A.

    Cell Signal. 2008 Aug;20(8):1409-14. Epub 2008 Jan 19. Review.

    PMID:
    18296024
    [PubMed - indexed for MEDLINE]
    3.

    A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.

    Hasegawa M, Matsushita Y, Horikawa M, Higashi K, Tomigahara Y, Kaneko H, Shirasaki F, Fujimoto M, Takehara K, Sato S.

    Arthritis Rheum. 2009 Nov;60(11):3465-75.

    PMID:
    19877032
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.

    Sonnylal S, Denton CP, Zheng B, Keene DR, He R, Adams HP, Vanpelt CS, Geng YJ, Deng JM, Behringer RR, de Crombrugghe B.

    Arthritis Rheum. 2007 Jan;56(1):334-44.

    PMID:
    17195237
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Mechanisms of skin fibrosis in systemic sclerosis.

    Jinnin M.

    J Dermatol. 2010 Jan;37(1):11-25. Review.

    PMID:
    20175837
    [PubMed - indexed for MEDLINE]
    6.

    TGFbeta, cardiac fibroblasts, and the fibrotic response.

    Leask A.

    Cardiovasc Res. 2007 May 1;74(2):207-12. Epub 2006 Jul 21. Review.

    PMID:
    16919613
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis.

    Ihn H.

    J Dermatol Sci. 2008 Feb;49(2):103-13. Epub 2007 Jul 12. Review.

    PMID:
    17628443
    [PubMed - indexed for MEDLINE]
    8.

    Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice.

    Liu X, Zhu S, Wang T, Hummers L, Wigley FM, Goldschmidt-Clermont PJ, Dong C.

    PLoS Med. 2005 Dec;2(12):e354. Epub 2005 Nov 1.

    PMID:
    16250671
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Systemic sclerosis: an update.

    Varga J.

    Bull NYU Hosp Jt Dis. 2008;66(3):198-202. Review.

    PMID:
    18937632
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Signaling in fibrosis: targeting the TGF beta, endothelin-1 and CCN2 axis in scleroderma.

    Leask A.

    Front Biosci (Elite Ed). 2009 Jun 1;1:115-22. Review.

    PMID:
    19482630
    [PubMed - indexed for MEDLINE]
    11.

    Transforming growth factor-beta signaling through the Smad proteins: role in systemic sclerosis.

    Verrecchia F, Mauviel A, Farge D.

    Autoimmun Rev. 2006 Oct;5(8):563-9. Epub 2006 Jul 5. Review.

    PMID:
    17027893
    [PubMed - indexed for MEDLINE]
    12.

    The role of endothelin-1 signaling in the fibrosis observed in systemic sclerosis.

    Leask A.

    Pharmacol Res. 2011 Jun;63(6):502-3. Epub 2011 Feb 17. Review.

    PMID:
    21315153
    [PubMed - indexed for MEDLINE]
    13.

    Vascular alterations upon activation of TGFbeta signaling in fibroblasts--implications for systemic sclerosis.

    Horn A, Distler JH.

    Arthritis Res Ther. 2010;12(3):125. Epub 2010 Jun 18.

    PMID:
    20602813
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    [Pathophysiologic aspects of systemic sclerosis].

    Gran JT, Molberg Ø, Midtvedt Ø.

    Tidsskr Nor Laegeforen. 2005 Oct 6;125(19):2622-3. Review. Norwegian.

    PMID:
    16215604
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Transforming growth factor-beta and angiotensin in fibrosis and burn injuries.

    Gabriel VA.

    J Burn Care Res. 2009 May-Jun;30(3):471-81. Review.

    PMID:
    19349880
    [PubMed - indexed for MEDLINE]
    16.

    Fibrillin in Marfan syndrome and tight skin mice provides new insights into transforming growth factor-beta regulation and systemic sclerosis.

    Lemaire R, Bayle J, Lafyatis R.

    Curr Opin Rheumatol. 2006 Nov;18(6):582-7. Review.

    PMID:
    17053502
    [PubMed - indexed for MEDLINE]
    17.

    Severe fibrosis and increased expression of fibrogenic cytokines in the gastric wall of systemic sclerosis patients.

    Manetti M, Neumann E, Milia AF, Tarner IH, Bechi P, Matucci-Cerinic M, Ibba-Manneschi L, Müller-Ladner U.

    Arthritis Rheum. 2007 Oct;56(10):3442-7.

    PMID:
    17907149
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Pro- and anti-fibrotic effects of TGF-beta in scleroderma.

    Sgonc R, Wick G.

    Rheumatology (Oxford). 2008 Oct;47 Suppl 5:v5-7. Review.

    PMID:
    18784145
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Animal models of scleroderma: lessons from transgenic and knockout mice.

    Derrett-Smith EC, Denton CP, Sonnylal S.

    Curr Opin Rheumatol. 2009 Nov;21(6):630-5. Review.

    PMID:
    19730378
    [PubMed - indexed for MEDLINE]
    20.

    Systemic sclerosis: current views of its pathogenesis.

    Derk CT, Jimenez SA.

    Autoimmun Rev. 2003 Jun;2(4):181-91. Review.

    PMID:
    12848944
    [PubMed - indexed for MEDLINE]

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