PubMed

Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans.

Stegenga ME, van der Crabben SN, Levi M, de Vos AF, Tanck MW, Sauerwein HP, van der Poll T.

Diabetes. 2006 Jun;55(6):1807-12.PMID: 16731846 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia prevents the suppressive effect of hyperinsulinemia on plasma adiponectin levels in healthy humans.

Blümer RM, van der Crabben SN, Stegenga ME, Tanck MW, Ackermans MT, Endert E, van der Poll T, Sauerwein HP.

Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E613-7. Epub 2008 Jun 24.PMID: 18577692 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia.

Stegenga ME, van der Crabben SN, Blümer RM, Levi M, Meijers JC, Serlie MJ, Tanck MW, Sauerwein HP, van der Poll T.

Blood. 2008 Jul 1;112(1):82-9. Epub 2008 Mar 3.PMID: 18316629 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute hyperglycemia and acute hyperinsulinemia decrease plasma fibrinolytic activity and increase plasminogen activator inhibitor type 1 in the rat.

Pandolfi A, Giaccari A, Cilli C, Alberta MM, Morviducci L, De Filippis EA, Buongiorno A, Pellegrini G, Capani F, Consoli A.

Acta Diabetol. 2001;38(2):71-6.PMID: 11757804 [PubMed - indexed for MEDLINE]Related articles

Activation of the tissue factor pathway of blood coagulation during prolonged hyperglycemia in young healthy men.

Rao AK, Chouhan V, Chen X, Sun L, Boden G.

Diabetes. 1999 May;48(5):1156-61.PMID: 10331423 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating tissue factor procoagulant activity and thrombin generation in patients with type 2 diabetes: effects of insulin and glucose.

Boden G, Vaidyula VR, Homko C, Cheung P, Rao AK.

J Clin Endocrinol Metab. 2007 Nov;92(11):4352-8. Epub 2007 Sep 4.PMID: 17785358 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of hyperinsulinemia combined with hyperglycemia and hypertriglyceridemia increases plasminogen activator inhibitor 1 in blood in normal human subjects.

Calles-Escandon J, Mirza SA, Sobel BE, Schneider DJ.

Diabetes. 1998 Feb;47(2):290-3.PMID: 9519730 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and changes in the blood coagulation-fibrinolysis system after a glucose clamp technique in patients with type 2 diabetes mellitus.

Takanashi K, Inukai T.

J Med. 2000;31(1-2):45-62.PMID: 10998755 [PubMed - indexed for MEDLINE]Related articles

Effects of hyperinsulinemia and hyperglycemia on lactate release and local blood flow in subcutaneous adipose tissue of healthy humans.

Henry S, Schneiter P, Jéquier E, Tappy L.

J Clin Endocrinol Metab. 1996 Aug;81(8):2891-5.PMID: 8768847 [PubMed - indexed for MEDLINE]Related articles

Effects of hyperglycemia and hyperinsulinemia on satiety in humans.

Gielkens HA, Verkijk M, Lam WF, Lamers CB, Masclee AA.

Metabolism. 1998 Mar;47(3):321-4.PMID: 9500570 [PubMed - indexed for MEDLINE]Related articles

Time-dependent effect of hyperglycemia and hyperinsulinemia on oxidative and non-oxidative glucose metabolism in patients with NIDDM.

Franssila-Kallunki AI, Eriksson JG, Groop LC.

Acta Endocrinol (Copenh). 1992 Aug;127(2):100-6.PMID: 1529656 [PubMed - indexed for MEDLINE]Related articles

Proinsulin, intact insulin, and fibrinolytic variables and fibrinogen in healthy subjects. A population study.

Eliasson M, Røder ME, Dinesen B, Evrin PE, Lindahl B.

Diabetes Care. 1997 Aug;20(8):1252-5.PMID: 9250449 [PubMed - indexed for MEDLINE]Related articles

Effect of insulin on basal and cholecystokinin-stimulated gallbladder motility in humans.

Gielkens HA, Lam WF, Coenraad M, Frölich M, van Oostayen JA, Lamers CB, Masclee AA.

J Hepatol. 1998 Apr;28(4):595-602.PMID: 9566827 [PubMed - indexed for MEDLINE]Related articles

Acute suppression of circulating sCD40L during hyperglycemia and euglycemic-hyperinsulinemia in healthy young males.

Oliver SR, Flores RL, Pontello AM, Rosa JS, Zaldivar FP, Galassetti PR.

J Investig Med. 2008 Oct;56(7):902-10.PMID: 18797414 [PubMed - indexed for MEDLINE]Related articles

Human plasma phospholipid transfer protein activity is decreased by acute hyperglycaemia: studies without and with hyperinsulinaemia in Type 1 diabetes mellitus.

Oomen PH, van Tol A, Hattori H, Smit AJ, Scheek LM, Dullaart RP.

Diabet Med. 2005 Jun;22(6):768-74.PMID: 15910630 [PubMed - indexed for MEDLINE]Related articles

Local insulin infusion stimulates expression of plasminogen activator inhibitor-1 and tissue-type plasminogen activator in normal subjects.

Carmassi F, Morale M, Ferrini L, Dell'Omo G, Ferdeghini M, Pedrinelli R, De Negri F.

Am J Med. 1999 Oct;107(4):344-50.PMID: 10527036 [PubMed - indexed for MEDLINE]Related articles

Determination of reference range values indicative of glucose metabolism and insulin resistance by use of glucose clamp techniques in horses and ponies.

Rijnen KE, van der Kolk JH.

Am J Vet Res. 2003 Oct;64(10):1260-4. Erratum in: Am J Vet Res. 2004 Mar;65(3):362. PMID: 14596464 [PubMed - indexed for MEDLINE]Related articles

Effects of all-trans retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibrinolysis in patients with acute promyelocytic leukemia.

Tallman MS, Lefèbvre P, Baine RM, Shoji M, Cohen I, Green D, Kwaan HC, Paietta E, Rickles FR.

J Thromb Haemost. 2004 Aug;2(8):1341-50.PMID: 15304040 [PubMed - indexed for MEDLINE]Related articles

Assessment of insulin resistance in newborn beagles with the euglycemic hyperinsulinemic clamp.

Hulman SE, Kliegman RM.

Pediatr Res. 1989 Feb;25(2):219-23.PMID: 2645563 [PubMed - indexed for MEDLINE]Related articles

Effects of hyperglycemia and hyperinsulinemia on circulating tissue factor procoagulant activity and platelet CD40 ligand.

Vaidyula VR, Rao AK, Mozzoli M, Homko C, Cheung P, Boden G.

Diabetes. 2006 Jan;55(1):202-8.PMID: 16380494 [PubMed - indexed for MEDLINE]Related articlesFree article